Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Martin Westermann"'
Autor:
Sneha Bhat, André Dietz, Katja Senf, Sandor Nietzsche, Yoshio Hirabayashi, Martin Westermann, Eva Maria Neuhaus
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background Olfactory sensory neurons detect odourants via multiple long cilia that protrude from their dendritic endings. The G protein-coupled receptor GPRC5C was identified as part of the olfactory ciliary membrane proteome, but its functi
Externí odkaz:
https://doaj.org/article/36affaac454245afaff522f93b42fceb
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 6 (2023)
ABSTRACT Lanthanides (Ln) are the most recently described life metals and are central to methylotrophy (type of metabolism in which organic substrates without carbon-carbon bonds serve as carbon and energy source) in diverse taxa. We recently charact
Externí odkaz:
https://doaj.org/article/097d2c882e364bb2983041688fd5db7b
Autor:
Sarah A. Hofbrucker-MacKenzie, Eric Seemann, Martin Westermann, Britta Qualmann, Michael M. Kessels
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Ultrahigh-resolution views of PIP2 in freeze-fractured plasma membranes of dendritic spines during induction of long-term depression reveal spatial and temporal cues set by PIP2 and reveal the molecular mechanisms behind the observed PIP2 dynamics
Externí odkaz:
https://doaj.org/article/8235a5478f724e75959cb5873b4b858b
Autor:
Miriana Battista, Bianca Hoffmann, Yann Bachelot, Lioba Zimmermann, Laura Teuber, Aurélie Jost, Susanne Linde, Martin Westermann, Mario M. Müller, Hortense Slevogt, Sven Hammerschmidt, Marc Thilo Figge, Cláudia Vilhena, Peter F. Zipfel
Publikováno v:
mSphere, Vol 8, Iss 4 (2023)
ABSTRACT Streptococcus pneumoniae-induced hemolytic uremic syndrome (Sp-HUS) is a kidney disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. This disease is frequently underdiagnosed and its pathophy
Externí odkaz:
https://doaj.org/article/287729874db041a79fe9e2085861f5e7
Autor:
Wisdom O. Maduabuchi, Felista L. Tansi, Bernd Faenger, Paul Southern, Quentin A. Pankhurst, Frank Steiniger, Martin Westermann, Ingrid Hilger
Publikováno v:
Cancers, Vol 16, Iss 1, p 33 (2023)
There is a growing interest in exploring the therapeutically mediated modulation of tumor vascularization of pancreatic cancer, which is known for its poorly perfused tumor microenvironment limiting the delivery of therapeutic agents to the tumor sit
Externí odkaz:
https://doaj.org/article/90a798cd23ae400bb99d1cf2dda7b142
Autor:
Anna Mittag, Alina Singer, Christian Hoera, Martin Westermann, Alexander Kämpfe, Michael Glei
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Zinc oxide nanoparticles (ZnO NP) offer beneficial properties for many applications, especially in the food sector. Consequently, as part of the human food chain, they are taken up orally. The toxicological evaluation of orally in
Externí odkaz:
https://doaj.org/article/bea5712e137946359bf2c89070a23394
Autor:
Christian Marx, Jürgen Sonnemann, Mandy Beyer, Oliver D. K. Maddocks, Sergio Lilla, Irene Hauzenberger, Andrea Piée‐Staffa, Kanstantsin Siniuk, Suneetha Nunna, Lisa Marx‐Blümel, Martin Westermann, Tobias Wagner, Felix B. Meyer, René Thierbach, Christina S. Mullins, Said Kdimati, Michael Linnebacher, Francesco Neri, Thorsten Heinzel, Zhao‐Qi Wang, Oliver H. Krämer
Publikováno v:
Molecular Oncology, Vol 15, Iss 12, Pp 3404-3429 (2021)
Late‐stage colorectal cancer (CRC) is still a clinically challenging problem. The activity of the tumor suppressor p53 is regulated via post‐translational modifications (PTMs). While the relevance of p53 C‐terminal acetylation for transcription
Externí odkaz:
https://doaj.org/article/0b74c48fb69942fab1d217753fe500f2
Autor:
Anke Siegmund, Muhammad Awais Afzal, Felix Tetzlaff, Daniela Keinhörster, Fabio Gratani, Kerstin Paprotka, Martin Westermann, Sandor Nietzsche, Christiane Wolz, Martin Fraunholz, Christian A. Hübner, Bettina Löffler, Lorena Tuchscherr
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1186-1198 (2021)
A large proportion of clinical S. aureus isolates that carry an inactive Agr system are associated with persistent infection that is difficult to treat. Once S. aureus is inside the bloodstream, it can cross the endothelial barrier and invade almost
Externí odkaz:
https://doaj.org/article/d2be581b9a5d43d987b9dcb1ebf0c0ca
Autor:
Christian Marx, Marc U. Schaarschmidt, Joanna Kirkpatrick, Lisa Marx-Blümel, Melisa Halilovic, Martin Westermann, Doerte Hoelzer, Felix B. Meyer, Yibo Geng, Katrin Buder, Hauke M. Schadwinkel, Kanstantsin Siniuk, Sabine Becker, René Thierbach, James F. Beck, Jürgen Sonnemann, Zhao-Qi Wang
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Introduction Ewing's sarcoma is an aggressive childhood malignancy whose outcome has not substantially improved over the last two decades. In this study, combination treatments of the HSP90 inhibitor AUY922 with either the ATR inhibitor VE82
Externí odkaz:
https://doaj.org/article/d8fb96d8e11f4e79b641bb5a2f9a1a6f
Autor:
Luke D. Halder, Emeraldo A. H. Jo, Mohammad Z. Hasan, Marta Ferreira-Gomes, Thomas Krüger, Martin Westermann, Diana I. Palme, Günter Rambach, Niklas Beyersdorf, Cornelia Speth, Ilse D. Jacobsen, Olaf Kniemeyer, Berit Jungnickel, Peter F. Zipfel, Christine Skerka
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Extracellular vesicles can carry immunoregulatory cytokines such as TGF-β. Here the authors use CD11b-deficient mice and macrophages to show that such vesicles carrying TGF-β are produced in response to Candida albicans infections and can limit the
Externí odkaz:
https://doaj.org/article/100b9457afd440a39a41c6760279cbb2