Electroretinography data from ovine models of CLN5 and CLN6 neuronal ceroid lipofuscinoses

Autor: Martin Wellby, Katharina N. Russell, Nadia L. Mitchell, Graham K. Barrell, David N. Palmer

Publikováno v: Data in Brief, Vol 37, Iss, Pp 107188-(2021)
Data in Brief

This article presents datasets associated with the research article entitled “Intravitreal gene therapy protects against retinal dysfunction and degeneration in sheep with CLN5 Batten disease” (Murray et al., [1] ). The neuronal ceroid lipofuscin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7cbdd697f3a2c5963a98bd3545d832
http://www.sciencedirect.com/science/article/pii/S2352340921004728

Expression of regulatory neuropeptides in the hypothalamus of red deer (Cervus elaphus) reveals anomalous relationships in the seasonal control of appetite and reproduction

Autor: Alda Pereira, M. J. Ridgway, Graham K. Barrell, Martin Wellby, Belinda A. Henry, Iain J. Clarke

Publikováno v: General and Comparative Endocrinology. 229:1-7

Red deer are seasonal with respect to reproduction and food intake, so we tested the hypothesis that their brains would show seasonal changes in numbers of cells containing hypothalamic neuropeptides that regulate these functions. We examined the bra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f8ec578f2189878d1107c2e5fc2cf2b
https://doi.org/10.1016/j.ygcen.2016.02.020

Nerve conduction velocity as a non-destructive biomarker in the earthworm Aporrectodea caliginosa exposed to insecticides

Autor: Martin Wellby, Ravi Gooneratne, Christophe Mazzia, Yvan Capowiez, Kiran Munir, Magali Rault

Publikováno v: Environmental Science and Pollution Research
Environmental Science and Pollution Research, Springer Verlag, 2018, 25 (24), pp.24362-24367. ⟨10.1007/s11356-018-2469-1⟩
Environmental Science and Pollution Research, 2018, 25 (24), pp.24362-24367. ⟨10.1007/s11356-018-2469-1⟩

International audience; Earthworms are important and useful soil organisms, but in agricultural soils, they are potentially exposed to a wide variety of pesticides. Insecticides represent the highest threat to earthworms and many are neurotoxic. Ther

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbaab98c29e346b230be175bf03f129c
https://hal-univ-avignon.archives-ouvertes.fr/hal-02089692

Computed tomography provides enhanced techniques for longitudinal monitoring of progressive intracranial volume loss associated with regional neurodegeneration in ovine neuronal ceroid lipofuscinoses

Autor: David N. Palmer, Nigel G. Anderson, Graham K. Barrell, Martin Wellby, Katharina N. Russell, Craig R. Bunt, Nadia L. Mitchell, Tracy R. Melzer

Publikováno v: Brain and Behavior

Introduction The neuronal ceroid lipofuscinoses (NCLs; Batten disease) are a group of fatal neurodegenerative lysosomal storage diseases of children caused by various mutations in a range of genes. Forms associated with mutations in two of these, CLN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca063be2b09b30a7b092efd368ba369f
https://doi.org/10.1002/brb3.1096

Absence of a causal relationship between environmental and body temperature in dairy cows (Bos taurus) under moderate climatic conditions

Autor: Martin Wellby, Wynand S. Verwoerd, Graham K. Barrell

Publikováno v: Journal of Thermal Biology. 31:533-540

1. Continuous body temperature records from dairy cows for 46 days of summer and contemporary data for climate temperature humidity index (THI) were analysed. 2. A large component of the body temperature data was not explained by changes in THI. 3. O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00386bc8cefb4addc5d01c32de3f92c5
https://doi.org/10.1016/j.jtherbio.2006.07.001