Design and Selection of Engineered Lytic Proteins With Staphylococcus aureus Decolonizing Activity

Autor: Diana Gutiérrez, Lorena Rodríguez-Rubio, Patricia Ruas-Madiedo, Lucía Fernández, Ana Belén Campelo, Yves Briers, Martin Weiss Nielsen, Karl Pedersen, Rob Lavigne, Pilar García, Ana Rodríguez

Publikováno v: Frontiers in Microbiology, Vol 12 (2021)

Staphylococcus aureus causes various infections in humans and animals, the skin being the principal reservoir of this pathogen. The widespread occurrence of methicillin-resistant S. aureus (MRSA) limits the elimination and treatment of this pathogen.

Externí odkaz: https://doaj.org/article/8d280d8d61ed4637a780c397773a7465

Pathology and bacteria related to digital dermatitis in dairy cattle in all year round grazing system in Brazil

Autor: Kirstine Klitgaard, Elias Jorge Facury Filho, Martin Weiss Nielsen, Tiago Facury Moreira, Antônio Último de Carvalho, Tim Kåre Jensen, Mikael Lenz Strube

Publikováno v: PLoS ONE, Vol 13, Iss 3, p e0193870 (2018)
PLoS ONE

Digital dermatitis (DD) is one of the main causes of lameness in dairy cattle worldwide, and it is frequently reported in high-yielding, free stall dairy herds from regions with a temperate climate. However, DD is also observed with high prevalence i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe120ab698e323f4d191795f30ed745
http://europepmc.org/articles/PMC5841792?pdf=render

A novel approach to probe host-pathogen interactions of bovine digital dermatitis, a model of a complex polymicrobial infection

Autor: Mette Boye, Martin Weiss Nielsen, Kirstine Klitgaard, Claus Schafer-Nielsen, Paolo Marcatili, Morten Nielsen, Thomas Sicheritz-Pontén, Tim Kåre Jensen

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Marcatili, P, Weiss Nielsen, M, Sicheritz-Pontén, T, Jensen, T K, Schafer-Nielsen, C, Boye, M, Nielsen, M & Schou, K K 2016, ' A novel approach to probe host-pathogen interactions of bovine digital dermatitis, a model of a complex polymicrobial infection ', BMC Genomics, vol. 17, no. 1, 987 . https://doi.org/10.1186/s12864-016-3341-7
BMC Genomics
Marcatili, P, Nielsen, M W, Sicheritz-Ponten, T, Jensen, T K, Schafer-Nielsen, C, Boye, M, Nielsen, M & Klitgaard, K 2016, ' A novel approach to probe host-pathogen interactions of bovine digital dermatitis, a model of a complex polymicrobial infection ', BMC Genomics, vol. 17, 987 . https://doi.org/10.1186/s12864-016-3341-7

Background: Polymicrobial infections represent a great challenge for the clarification of disease etiology and the development of comprehensive diagnostic or therapeutic tools, particularly for fastidious and difficult-to-cultivate bacteria. Using bo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::080e0bbb7bdc8069d4c43fa14040fdd1
https://doi.org/10.1186/s12864-016-3341-7

Potential bacterial core species associated with digital dermatitis in cattle herds identified by molecular profiling of interdigital skin samples

Autor: Mikael Lenz Strube, Mette Boye, Martin Weiss Nielsen, Tim Kåre Jensen, Kirstine Klitgaard, Worood D.H.M. Al-Medrasi, Anastasia Isbrand

Publikováno v: Weiss Nielsen, M, Strube, M L, Isbrand, A, Al-Medrasi, W D H M, Boye, M, Jensen, T K & Schou, K K 2016, ' Potential bacterial core species associated with digital dermatitis in cattle herds identified by molecular profiling of interdigital skin samples ', Veterinary Microbiology, vol. 186, pp. 139-149 . https://doi.org/10.1016/j.vetmic.2016.03.003

Although treponemes are consistently identified in tissue from bovine digital dermatitis (DD) lesions, the definitive etiology of this debilitating polymicrobial disease is still unresolved. To study the microbiomes of 27 DD-infected and 10 healthy i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090521353596f4bcdc24892bfd7094f2
https://orbit.dtu.dk/en/publications/6b69e52e-0fd2-44a8-a853-8a17c9c9fa88

Masking of the CD3γ di-Leucine-based Motif by ζ is Required for Efficient T-Cell Receptor Expression

Autor: Carsten Geisler, Jens Peter H. Lauritsen, Niels Ødum, Anette Bødker Rasmussen, Martin Weiss Nielsen, Marina Rode von Essen, Charlotte M. Bonefeld, Jes Dietrich

Publikováno v: Traffic. 5:672-684

The T-cell receptor (TCR) is a multimeric receptor composed of the Ti alpha beta heterodimer and the noncovalently associated CD3 gamma delta epsilon and zeta(2) chains. All of the TCR chains are required for efficient cell surface expression of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c6cabd95042e74818409b569eb460b25
https://doi.org/10.1111/j.1600-0854.2004.00211.x