Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Martin W. Elmlinger"'
Autor:
Doris Oesterle, Martin W. Elmlinger, Esther Hessel, Andreas Hoeflich, Martina Langhammer, Ingrid Renner-Müller, Harald Lahm, Daniela Diehl, Eckhard Wolf, Martin Göttlicher
Publikováno v:
International Journal of Cancer. 124:2220-2225
Colon cancer patients frequently show increased levels of serum insulin-like growth factor-binding protein-2 (IGFBP-2), however, the pathogenetic relevance of this phenomenon for colorectal cancer is unclear. Therefore, we have used IGFBP-2 transgeni
Autor:
Cecilia Camacho-Hübner, Reinhold G. Erben, Corinna Moerth, I Renner-Mueller, Eckhard Wolf, Martin W. Elmlinger, Andreas Hoeflich, Marlon R. Schneider, Andreas Blutke
Publikováno v:
Endocrinology. 148:441-451
This study tested whether elevated levels of IGF-II in the postnatal period can rescue the dwarfism in IGF-I-deficient mice. Heterozygous Igf1 mutant mice [I+/− IIwt] were crossed with heterozygous Igf1 mutant, phosphoenolpyruvate carboxykinase pro
Autor:
Miodrag Stojkovic, Martina Klempt, Myriam Weppert, Martin W. Elmlinger, Oliver J. Schmitz, Eckhard Wolf, Michaela Wirtz, Stefan Hiendleder, Frank Lyko, H.-D. Reichenbach, Cora Mund, Hendrik Wenigerkind
Publikováno v:
Biology of Reproduction. 75:17-23
Epigenetic perturbations are assumed to be responsible for phenotypic abnormalities of fetuses and offspring originating from in vitro embryo techniques. We studied 29 viable Day-80 bovine fetuses to assess the effects of two in vitro fertilization p
Autor:
Sabine Nedbal, Eckhard Wolf, Lutz Bünger, Martin W. Elmlinger, Andreas Hoeflich, Charlotte Bruley, Ulla Renne, Werner F. Blum, Helmut J. Kolb
Publikováno v:
General and Comparative Endocrinology. 136:248-259
Transgenic and knockout models have been used successfully in order to attribute specific functions to distinct growth factors. However, it is not clear which from the different IGF-components are actually altered when growth is affected. Furthermore
Autor:
W. Hamish B. Wallace, P. M. Crofton, Louise Bath, Martin W. Elmlinger, Agnes E M Evans, Michael B. Ranke, Christopher J. H. Kelnar
Publikováno v:
Pediatric Research. 55:224-230
Children who are treated for malignancy have been shown to have decreased bone mineral density. We investigated the effect of serial courses of chemotherapy on growth and bone turnover in children with solid tumors. We measured height, weight, and lo
Publikováno v:
Hormone Research in Paediatrics. 62:33-39
Objective: To investigate the role of the insulin-like growth factors (IGF) system during the differentiation of human pulp-derived fibroblasts (HPF). Methods: Primary HPF were cultured for 24 days in DMEM medium with IGF-I or IGF-II (50 ng/ml each).
Autor:
Z. Hussain, Martin W. Elmlinger, Stephan Coerper, Silvia Wagner, Thomas K. Hunt, Horst D. Becker, Jurgen E. Mueller, Jens Fricke
Publikováno v:
Wound Repair and Regeneration. 11:253-260
Inflammatory cells are generally assumed to be the primary source of most growth factors/cytokines that participate in wound healing. Correspondingly, most attempts to enhance wound healing have been directed at the wound itself. However, certain key
Publikováno v:
Growth Hormone & IGF Research. 13:75-80
Objective . The aim of this study is to adapt measurements of IGF-I, IGFBP-2 and IGFBP-3 to dried blood filter disk assays. Methods . Measurements of the three analytes in serum samples and in the corresponding blood spotted onto filter paper were co
Autor:
B.S. Schuett, Wolfgang Weidemann, Gabriela Romalo, Martin W. Elmlinger, Michael B. Ranke, D. Diesing, H.U. Schweikert, Klaus-Dieter Spindler
Publikováno v:
Hormone Research in Paediatrics. 60:73-78
Background: We investigated the effects of androgens, estradiol (E2) and insulin-like growth factor (IGF)-I on IGF-II, insulin-like growth factor binding protein (IGFBP)-2, -3 and -5 and mRNA in genital fibroblasts (GF) from patients with complete an
Autor:
Roland Schweizer, Bertram Flehmig, Martin W. Elmlinger, Klaus-Peter Maier, Bernd Stadler, Michael B. Ranke, Sabine Schleicher
Publikováno v:
Hormone Research in Paediatrics. 60:174-180
Background/Aims: Insulin-like growth factor-binding protein-2 (IGFBP-2) is expressed in many malignant tissues, and elevated serum levels can be indicators of tumour activity in addition to conventional tumour markers. Our aim was to evaluate the rol