Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Martin Vezina"'
Autor:
Nadia Fortin, Carl Saint-Louis, Annick Landry, René Gagnon, Gilles Olsen, Sylvain Bernard, Patrick Bherer, Eric Marsault, Véronique Plourde, Gilles Berthiaume, Martin Brassard, Robert Deziel, Axel Mathieu, Gérald Villeneuve, Xiaowen Peng, Hamid R. Hoveyda, Mark Peterson, Graeme L. Fraser, François Bilodeau, Ruoxi Lan, Shridhar Bhat, Annie Doucet, Maude Gauthier, Yves L. Dory, David Lonergan, Shigui Li, Sylvie Beaubien, Luc Ouellet, Pierre Deslongchamps, Alexandre Drouin, Fabrice Galaud, Sophie Beauchemin, Manon Champagne, Kamel Benakli, Mahesh Ramaseshan, Laurence Foucher, Jean François Pinault, Martin Vezina, Daniel Fortin, Zhigang Wang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:4731-4735
A new method for solid phase parallel synthesis of chemically and conformationally diverse macrocyclic peptidomimetics is reported. A key feature of the method is access to broad chemical and conformational diversity. Synthesis and mechanistic studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf941f5cc5a05130451a2464ff661573
https://doi.org/10.1016/j.bmcl.2008.06.085
https://doi.org/10.1016/j.bmcl.2008.06.085
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783319208008
ICIAR
ICIAR
Available color images can be encoded in any color space. However, according to the image display model, it is assumed that the color image is encoded in a specific color space belonging to the RGB family. Displaying an encoded image in a color space
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d5ba0927c8ad6961b21acb26642ccee
https://doi.org/10.1007/978-3-319-20801-5_51
https://doi.org/10.1007/978-3-319-20801-5_51
Autor:
Eric Marsault, Kamel Benakli, Graeme L. Fraser, Annick Landry, Sophie Beauchemin, Mahesh Ramaseshan, Laurence Foucher, Xiaowen Peng, Jean François Pinault, Martin Brassard, Daniel F. Veber, Martin Vezina, René Gagnon, Shridhar Bhat, Hamid R. Hoveyda, Carl Saint-Louis, Mark Peterson, Patrick Bherer, Sylvie Beaubien, Axel Mathieu, Luc Ouellet, Zhigang Wang
Publikováno v:
Journal of medicinal chemistry. 54(24)
High-throughput screening of Tranzyme Pharma's proprietary macrocycle library using the aequorin Ca2+-bioluminescence assay against the human ghrelin receptor (GRLN) led to the discovery of novel agonists against this G-protein coupled receptor. Earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d338a7eaed3c1a1e5dec403cfa4d2f29
https://pubmed.ncbi.nlm.nih.gov/22106937
https://pubmed.ncbi.nlm.nih.gov/22106937
Autor:
Hamid R. Hoveyda, Eric Marsault, Martin Vezina, Laurence Foucher, Kamel Benakli, Hugo Tremblay, Sylvie Beaubien
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387736563
Introduction As part of our efforts towards the development of methodologies for the parallel synthesis of small molecule macrocyclic peptidomimetics, we report a new application of Ru-catalyzed ring-closing metathesis (RCM) cyclative-release for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d847b9ab78938bf8c0c3576414f885d1
https://doi.org/10.1007/978-0-387-73657-0_6
https://doi.org/10.1007/978-0-387-73657-0_6
Autor:
Martin Vézina
Dans les nouvelles de ce recueil, les thèmes abordés sont classiques et universels : l'amour et la mort, dont les pas complexes s'entremêlent dans un tango déchirant dansé sur la piste souvent trop étroite du quotidien. Les rencontres, qu'elles
Autor:
Hamid R. Hoveyda, Carl Saint-Louis, Theo Peeters, Zhigang Wang, Martin Vezina, Robert Deziel, Graeme L. Fraser, Sylvie Beaubien, Annick Landry, Luc Ouellet, Eric Marsault, Mark Peterson, Sophie Beauchemin, Mahesh Ramaseshan, Kamel Benakli
Publikováno v:
Journal of medicinal chemistry. 49(24)
A novel class of macrocyclic peptidomimetics was identified and optimized as potent antagonists to the human motilin receptor (hMOT-R). Well-defined structure-activity relationships allowed for rapid optimization of potency that eventually led to hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935ca7584da8bbf469dd5fe442847841
https://pubmed.ncbi.nlm.nih.gov/17125271
https://pubmed.ncbi.nlm.nih.gov/17125271
Autor:
Hamid Hoveyda, Martin Vezina
Publikováno v:
Organic letters. 7(11)
[reaction: see text]. A two-step synthesis of N-protected unsaturated amino alcohols is disclosed that relies on an unexpectedly selective cross-metathesis (CM) involving allyl cyanide and pent-4-en-1-ol. The solution concentration and the identity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dac705ebff6dabedd6432c4f4e47104
https://pubmed.ncbi.nlm.nih.gov/15901147
https://pubmed.ncbi.nlm.nih.gov/15901147