Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Martin Uhrbom"'
Autor:
Martin Uhrbom, Lars Muhl, Guillem Genové, Jianping Liu, Henrik Palmgren, Ida Alexandersson, Fredrik Karlsson, Alex-Xianghua Zhou, Sandra Lunnerdal, Sonja Gustafsson, Byambajav Buyandelger, Kasparas Petkevicius, Ingela Ahlstedt, Daniel Karlsson, Leif Aasehaug, Liqun He, Marie Jeansson, Christer Betsholtz, Xiao-Rong Peng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Cell identities are defined by intrinsic transcriptional networks and spatio-temporal environmental factors. Here, we explored multiple factors that contribute to the identity of adipose stem cells, including anatomic location, microvascular
Externí odkaz:
https://doaj.org/article/1b79a0f896454151b3ae472ae9fc9feb
Autor:
Carlijn A Hoekx, Borja Martinez-Tellez, Maaike E Straat, Magdalena M A Verkleij, Mirjam Kemmeren, Sander Kooijman, Martin Uhrbom, Saskia C A de Jager, Patrick C N Rensen, Mariëtte R Boon
Publikováno v:
Endocrine Connections, Vol 13, Iss 7, Pp 1-10 (2024)
Objectives: Cold exposure is linked to cardiometabolic benefits. Cold activates brown adipose tissue (BAT), increases energy expenditure, and induces secretion of the hormones fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (
Externí odkaz:
https://doaj.org/article/0be410fb04c2444f94093ce16ab04b39
Autor:
Kasparas Petkevicius, Henrik Palmgren, Matthew S. Glover, Andrea Ahnmark, Anne-Christine Andréasson, Katja Madeyski-Bengtson, Hiroki Kawana, Erik L. Allman, Delaney Kaper, Martin Uhrbom, Liselotte Andersson, Leif Aasehaug, Johan Forsström, Simonetta Wallin, Ingela Ahlstedt, Renata Leke, Daniel Karlsson, Hernán González-King, Lars Löfgren, Ralf Nilsson, Giovanni Pellegrini, Nozomu Kono, Junken Aoki, Sonja Hess, Grzegorz Sienski, Marc Pilon, Mohammad Bohlooly-Y, Marcello Maresca, Xiao-Rong Peng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The regulation of cellular phosphatidylethanolamine (PE) acyl chain composition is poorly understood. Here, the authors show that TLCD1 and TLCD2 proteins mediate the formation of monounsaturated fatty acid-containing PE species and promote the progr
Externí odkaz:
https://doaj.org/article/15464563b39b4d54986a8c040d9d92b8
Autor:
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik JP van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andreasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick CN Rensen
Publikováno v:
eLife, Vol 12 (2023)
Analogues of the hepatokine fibroblast growth factor 21 (FGF21) are in clinical development for type 2 diabetes and nonalcoholic steatohepatitis (NASH) treatment. Although their glucose-lowering and insulin-sensitizing effects have been largely unrav
Externí odkaz:
https://doaj.org/article/10b3762987d94deeac6dedce6336b7ac
Autor:
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik JP van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andreasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick CN Rensen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b99d425453df9a925aa60e01e5fc280
https://doi.org/10.7554/elife.83075.sa2
https://doi.org/10.7554/elife.83075.sa2
Autor:
Cong Liu, Milena Schönke, Borah Spoorenberg, Joost M Lambooij, Hendrik JP van der Zande, Enchen Zhou, Maarten E Tushuizen, Anne-Christine Andreasson, Andrew Park, Stephanie Oldham, Martin Uhrbom, Ingela Ahlstedt, Yasuhiro Ikeda, Kristina Wallenius, Xiao-Rong Peng, Bruno Guigas, Mariëtte R Boon, Yanan Wang, Patrick CN Rensen
Analogues of the hepatokine FGF21 are in clinical development for type 2 diabetes and nonalcoholic steatohepatitis (NASH) treatment. Although their glucose-lowering and insulin-sensitizing effects have been largely unraveled, the mechanisms by which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e6766169da40861a1df700705827a6
https://doi.org/10.1101/2022.09.20.508654
https://doi.org/10.1101/2022.09.20.508654
Autor:
Rakesh Puttreddy, Kari Rissanen, Anna-Carin C. Carlsson, Michele Bedin, Alavi Karim, Bijan Nekoueishahraki, Alexei A. Neverov, Jürgen Gräfenstein, Martin Uhrbom, Krenare Mehmeti, Máté Erdélyi, Roland Kleinmaier
Publikováno v:
Journal of the American Chemical Society
We have investigated the influence of electron density on the three-center [N-I-N](+) halogen bond. A series of [bis(pyri din e) io dine](+) and [1,2-bis ( (pyridin e-2-71 ethynyl)b e nze n e)io dine](+) BF4- complexes substituted with electron withd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b789a91656a86e2b161e52299158099a
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-303055
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-303055
Autor:
Claes Dahlgren, Michael Gabl, Sunil K. Pandey, Martin Uhrbom, Huamei Forsman, Malene Winther, Trond Ulven, Lena Björkman, Anders Højgaard Hansen, Jonas Mårtensson, Johan Bylund, André Holdfeldt
Publikováno v:
Björkman, L, Mårtensson, J, Winther, M, Gabl, M, Holdfeldt, A, Uhrbom, M, Bylund, J, Højgaard Hansen, A, Pandey, S K, Ulven, T, Forsman, H & Dahlgren, C 2016, ' The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment ', Molecular and Cellular Biology, vol. 36, no. 20, pp. 2583-2595 . https://doi.org/10.1128/MCB.00161-16
Ligands with improved potency and selectivity for free fatty acid receptor 2 (FFA2R) have become available, and we here characterize the neutrophil responses induced by one such agonist (Cmp1) and one antagonist (CATPB). Cmp1 triggered an increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25f897c12e511a79ca178764e3319876
https://findresearcher.sdu.dk:8443/ws/files/125902813/The_Neutrophil_Response_Induced_by_an_Agonist_for_Free_Fatty_Acid_Receptor_2_GPR43_Is_Primed_by_Tumor_Necrosis_Factor_Alpha_and_by_Receptor_Uncoupling_from_the_Cytoskeleton_but_Attenuated_by_Tissue_Recruitment.pdf
https://findresearcher.sdu.dk:8443/ws/files/125902813/The_Neutrophil_Response_Induced_by_an_Agonist_for_Free_Fatty_Acid_Receptor_2_GPR43_Is_Primed_by_Tumor_Necrosis_Factor_Alpha_and_by_Receptor_Uncoupling_from_the_Cytoskeleton_but_Attenuated_by_Tissue_Recruitment.pdf
Autor:
Alavi Karim, Jürgen Gräfenstein, Martin Uhrbom, Anna-Carin C. Carlsson, Máté Erdélyi, Ulrika Brath
Publikováno v:
CrystEngComm
The symmetric arrangement of the iodine and bromine centred 3-center–4-electron halogen bond is revealed to remain preferred in a polar, aprotic solvent environment. Acetonitrile is unable to compete with pyridine for halogen bonding; however, its