Zobrazeno 1 - 10
of 265
pro vyhledávání: '"Martin U Schuhmann"'
Autor:
Azadeh Ebrahimi, Andreas Waha, Jens Schittenhelm, Georg Gohla, Martin U Schuhmann, Torsten Pietsch
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-6 (2024)
Abstract Methylation class “CNS tumor with BCOR/BCOR(L1)-fusion” was recently defined based on methylation profiling and tSNE analysis of a series of 21 neuroepithelial tumors with predominant presence of a BCOR fusion and/or characteristic CNV b
Externí odkaz:
https://doaj.org/article/92fcd0a00ff14cf69c66db510b0f1ecd
Autor:
Romain Sigaud, Thomas K. Albert, Caroline Hess, Thomas Hielscher, Nadine Winkler, Daniela Kocher, Carolin Walter, Daniel Münter, Florian Selt, Diren Usta, Jonas Ecker, Angela Brentrup, Martin Hasselblatt, Christian Thomas, Julian Varghese, David Capper, Ulrich W. Thomale, Pablo Hernáiz Driever, Michèle Simon, Svea Horn, Nina Annika Herz, Arend Koch, Felix Sahm, Stefan Hamelmann, Augusto Faria-Andrade, Nada Jabado, Martin U. Schuhmann, Antoinette Y. N. Schouten-van Meeteren, Eelco Hoving, Tilman Brummer, Cornelis M. van Tilburg, Stefan M. Pfister, Olaf Witt, David T. W. Jones, Kornelius Kerl, Till Milde
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Pediatric low-grade gliomas (pLGG) show heterogeneous responses to MAPK inhibitors (MAPKi) in clinical trials. Thus, more complex stratification biomarkers are needed to identify patients likely to benefit from MAPKi therapy. Here, we identi
Externí odkaz:
https://doaj.org/article/87e41da8f9f6492d937e992bb05c9817
Autor:
Maximilian Iller, Felix Neunhoeffer, Lukas Heimann, Julian Zipfel, Martin U. Schuhmann, Simon Scherer, Markus Dietzel, Joerg Fuchs, Michael Hofbeck, Stefanie Hieber, Frank Fideler
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionInducing general anesthesia (GA) in children can considerably affect blood pressure, and the rate of severe critical events owing to this remains high. Cerebrovascular autoregulation (CAR) protects the brain against blood-flow-related inj
Externí odkaz:
https://doaj.org/article/66593347078143bab55306c4594656b3
Autor:
Maximilian Y. Deng, Dominik Sturm, Elke Pfaff, Martin Sill, Damian Stichel, Gnana Prakash Balasubramanian, Stephan Tippelt, Christof Kramm, Andrew M. Donson, Adam L. Green, Chris Jones, Jens Schittenhelm, Martin Ebinger, Martin U. Schuhmann, Barbara C. Jones, Cornelis M. van Tilburg, Andrea Wittmann, Andrey Golanov, Marina Ryzhova, Jonas Ecker, Till Milde, Olaf Witt, Felix Sahm, David Reuss, David Sumerauer, Josef Zamecnik, Andrey Korshunov, Andreas von Deimling, Stefan M. Pfister, David T. W. Jones
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Radiation-induced gliomas (RIGs) have been reported in patients after treatment with cranial irradiation for various primary malignancies but their origin are still unclear. Here, the authors define the genomic, epigenetic and transcriptional landsca
Externí odkaz:
https://doaj.org/article/d294b00cf8014bf897f67d7d3d39f257
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-8 (2021)
Abstract Background Idiopathic normal pressure hydrocephalus (iNPH) and late-onset idiopathic aqueductal stenosis (LIAS) are two forms of chronic adult hydrocephalus of different aetiology. We analysed overnight intracranial pressure (ICP) monitoring
Externí odkaz:
https://doaj.org/article/fd643e9ccdfd424c990ca8fc4d48c61b
Publikováno v:
Children, Vol 9, Iss 4, p 490 (2022)
Vestibular schwannomas (VS) usually manifest between the 5th and 8th decade of life. Most pediatric cases are associated with Neurofibromatosis type 2 and sporadic VS are rare in this age group. Few case series have been published. We report on our i
Externí odkaz:
https://doaj.org/article/8449f4f9d3494bd2a23be8fd5e4fed90
Autor:
David Gorodezki, Julian Zipfel, Manon Queudeville, Ursula Holzer, Andrea Bevot, Jens Schittenhelm, Thomas Nägele, Martin U. Schuhmann, Martin Ebinger
Publikováno v:
International Journal of Cancer. 152:1875-1883
In addition to surgical management, corticosteroids have proven to be beneficial in the management of acute symptoms related to CNS tumors, and have been widely used for many decades, with dexamethasone (DM) representing the most commonly used agent.
Autor:
David Gorodezki, Julian Zipfel, Manon Queudeville, Jordana Sosa, Ursula Holzer, Jan Kern, Andrea Bevot, Jens Schittenhelm, Thomas Nägele, Martin Ebinger, Martin U. Schuhmann
Publikováno v:
Journal of Neuro-Oncology. 160:567-576
Purpose Despite excellent long-term overall survival rates, pediatric low-grade gliomas (pLGG) show high variety of clinical behavior regarding progress or senescence post incomplete resection (IR). This study retrospectively analyzes tumor growth ve
Autor:
Deborah Staber, Julia Oppold, Alexander Grimm, Martin U. Schuhmann, Alyssa Romano, Justus Marquetand, Benedict Kleiser
Publikováno v:
Diagnostics, Vol 12, Iss 2, p 360 (2022)
Ultrasound shear wave elastography (SWE) is an increasingly used imaging modality that expands clinical ultrasound by measuring the elasticity of various tissues, such as the altered elasticity of tumors. Peripheral nerve tumors are rare, have been w
Externí odkaz:
https://doaj.org/article/5be97baf2f36472ebafe33d340f4ef4f
Autor:
Julian Zipfel, Berit Wikidal, Bernadett Schwaneberg, Martin U. Schuhmann, Harry Magunia, Michael Hofbeck, Christian Schlensak, Simon Schmid, Felix Neunhoeffer
Publikováno v:
Pediatric Anesthesia. 32:1320-1329
Advances in the treatment of pediatric congenital heart disease have increased survival rates. Despite efforts to prevent neurological injury, many patients suffer from impaired neurodevelopmental outcomes. Compromised cerebral autoregulation can inc