Distinct genomic routes underlie transitions to specialised symbiotic lifestyles in deep-sea annelid worms

Autor: Giacomo Moggioli, Balig Panossian, Yanan Sun, Daniel Thiel, Francisco M. Martín-Zamora, Martin Tran, Alexander M. Clifford, Shana K. Goffredi, Nadezhda Rimskaya-Korsakova, Gáspár Jékely, Martin Tresguerres, Pei-Yuan Qian, Jian-Wen Qiu, Greg W. Rouse, Lee M. Henry, José M. Martín-Durán

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)

Abstract Bacterial symbioses allow annelids to colonise extreme ecological niches, such as hydrothermal vents and whale falls. Yet, the genetic principles sustaining these symbioses remain unclear. Here, we show that different genomic adaptations und

Externí odkaz: https://doaj.org/article/15074cb9f5a240089010f85ad8c9f758

Using home monitoring technology to study the effects of traumatic brain injury on older multimorbid adults: protocol for a feasibility study

Autor: Paresh Malhotra, David J Sharp, Yuchen Zhao, Michael David, David Sharp, Michael Fertleman, Lenny Naar, Sarah Daniels, Ramin Nilforooshan, Derk-Jan Dijk, Claire Norman, Greg Scott, Ian Williams, John Patterson, Neil Graham, David Wingfield, Mara Golemme, Melanie Dani, Sanara Raza, Lucia M Li, Sumit Dey, Eyal Soreq, Payam Barnaghi, Martina Del Giovane, Magdalena Kolanko, Ciro Della Monica, Helen Lai, Tong Wu, Megan E Parkinson, Danielle Wilson, Zaynab Ismail, Paul Freemont, Ravi Vaidyanathan, Tim Constandinou, Naomi Hassim, Mark Crook Rumsey, Emma Jane Mallas, Alina-Irina Serban, Alan Bannon, Shlomi Haar, Charalambos Hadjipanayi, Ghena Hammour, Bryan Hsieh, Adrien Rapeaux, Maowen Yin, Maria Lima, Maitreyee Wairagkar, Nan Fletcher-Lloyd, Hamed Haddadi, Valentinas Janeiko, Anna Joffe, Samaneh Kouchaki, Viktor Levine, Honglin Li, Amer Marzuki, Francesca Palermo, Mark Woodbridge, Alexander Capstick, Severin Skillman, Loren Cameron, Michael Crone, Kirsten Jensen, Anne Skeldon, Kevin Wells, Ullrich Bartsch, Kiran G R Kumar, Damion Lambert, Sara Mohammadi Mahvash, Thalia Rodriguez Garcia, Martin Tran, Thomas Adam, Vikki Revell, Giuseppe Atzori, Lucinda Grainger, Hana Hassanin, James Woolley, Iris Wood-Campar, Janetta Rexha, Sophie Horrocks, Brian Quan, Jessica True, Olga Balazikova, Emily Beale, Vaiva Zarombaite, Lucy Copps, Olivia Knight, Gaganpreet Bangar, Chelsea Mukonda, Jessica Hine, Luke Mallon, Anesha Patel, Ruby Lyall, Pippa Kirby, Mike Law, Andy Kenny

Publikováno v: BMJ Open, Vol 13, Iss 5 (2023)

Introduction The prevalence of traumatic brain injury (TBI) among older adults is increasing exponentially. The sequelae can be severe in older adults and interact with age-related conditions such as multimorbidity. Despite this, TBI research in olde

Externí odkaz: https://doaj.org/article/7ac3b4d583fb40b7a0a33329f530b719

Role of MXD3 in proliferation of DAOY human medulloblastoma cells.

Autor: Gustavo A Barisone, Tin Ngo, Martin Tran, Daniel Cortes, Mehdi H Shahi, Tuong-Vi Nguyen, Daniel Perez-Lanza, Wanna Matayasuwan, Elva Díaz

Publikováno v: PLoS ONE, Vol 7, Iss 7, p e38508 (2012)

A subset of medulloblastomas, the most common brain tumor in children, is hypothesized to originate from granule neuron precursors (GNPs) in which the sonic hedgehog (SHH) pathway is over-activated. MXD3, a basic helix-look-helix zipper transcription

Externí odkaz: https://doaj.org/article/33c07eab57864cfdbe4b21ae7ce12358

Embryo model completes gastrulation to neurulation and organogenesis

Autor: Gianluca Amadei, Charlotte E. Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, Martin Tran, Beth K. Martin, Dong-Yuan Chen, Alejandro Aguilera-Castrejon, Jacob H. Hanna, Michael B. Elowitz, Florian Hollfelder, Jay Shendure, David M. Glover, Magdalena Zernicka-Goetz

Embryonic stem (ES) cells can undergo many aspects of mammalian embryogenesis in vitro1–5, but their developmental potential is substantially extended by interactions with extraembryonic stem cells, including trophoblast stem (TS) cells, extraembry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41f27ede82df3fe7402f34c678cf5ff
https://resolver.caltech.edu/CaltechAUTHORS:20221010-454096500.25

Annelid functional genomics reveal the origins of bilaterian life cycles

Autor: Francisco M. Martín-Zamora, Yan Liang, Kero Guynes, Allan M. Carrillo-Baltodano, Billie E. Davies, Rory D. Donnellan, Yongkai Tan, Giacomo Moggioli, Océane Seudre, Martin Tran, Kate Mortimer, Nicholas M. Luscombe, Andreas Hejnol, Ferdinand Marlétaz, José M. Martín-Durán

Publikováno v: bioRxiv

Indirect development with an intermediate larva exists in all major animal lineages1, which makes larvae central to most scenarios of animal evolution2–11. Yet how larvae evolved remains disputed. Here we show that temporal shifts (that is, heteroc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774a5cb8cb1ed0378b9110e474479824
https://doi.org/10.1101/2022.02.05.479245