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pro vyhledávání: '"Martin Tomaško"'
Publikováno v:
FEBS Journal. 279:29-39
8-Oxoguanine is a ubiquitous oxidative base lesion. We report here on the effect of this lesion on the structure and stability of quadruplexes formed by the human telomeric DNA sequence 5'-dG(3)(TTAG(3))(3) in NaCl and KCl. CD, PAGE and absorption-ba
Quadruplexes of human telomere DNA analogs designed to contain G:A:G:A, G:G:A:A, and A:A:A:A tetrads
Publikováno v:
Biopolymers. 93(10)
Replacement of two to four guanines by adenines in the human telomere DNA repeat dG3(TTAG3)3 did not hinder the formation of quadruplexes if the substitutions took place in the terminal tetrad bridged by the diagonal loop of the intramolecular antipa
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 31:28-28
In addition to the well-known Watson–Crick double helix, DNA can form other structures. One of them is a four-stranded quadruplex, formation of which was also acknowledged in in vivo conditions. It was suggested that the presence of quadruplexes in