Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Martin Tobias Kaminski"'
Publikováno v:
Biochemical and Biophysical Research Communications. 464:13-19
In the new human EndoC-βH1 β-cell line, a detailed analysis of the physiological characteristics was performed. This new human β-cell line expressed all target structures on the gene and protein level, which are crucial for physiological function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3faf18d827f4b354e1d11638deccc616
https://doi.org/10.1016/j.bbrc.2015.05.072
https://doi.org/10.1016/j.bbrc.2015.05.072
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1823:1697-1707
Glucose is the physiological stimulus for insulin secretion in pancreatic beta cells. The uptake and phosphorylation of glucose initiate and control downstream pathways, resulting in insulin secretion. However, the temporal coordination of these even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92134cd16c36951e5ce09dd6f8590c0b
https://doi.org/10.1016/j.bbamcr.2012.06.022
https://doi.org/10.1016/j.bbamcr.2012.06.022
Publikováno v:
Molecular Endocrinology. 24:1988-1997
Glucokinase (GK) plays a crucial role as glucose sensor in glucose-induced insulin secretion in pancreatic β-cells. The bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) acts as an endogenous GK activator. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02bd47a25ec1fc39674dabc21e3e3ad3
https://doi.org/10.1210/me.2010-0115
https://doi.org/10.1210/me.2010-0115
Autor:
Sigurd Lenzen, Markus Tiedge, Martin Tobias Kaminski, Simone Baltrusch, Rica Waterstradt, Julia Schultz
Publikováno v:
Biochimica et biophysica acta. 1843(3)
The glucose phosphorylating enzyme glucokinase regulates glucose metabolism in the liver. Glucokinase activity is modulated by a liver-specific competitive inhibitor, the glucokinase regulatory protein (GRP), which mediates sequestration of glucokina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fe61c9a5b972c2ac771e2899cf8d40
https://pubmed.ncbi.nlm.nih.gov/24333860
https://pubmed.ncbi.nlm.nih.gov/24333860