Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Martin T. Schaerer"'
Autor:
William A. Blumentals, Martin T. Schaerer, Miriam Adamcova, Gabriel Vital-Durand, Pia Suter, Patricia Schlagenhauf, Loredana Regep, Hans-Georg Rhein, Margarita Suarez Boutros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2740441a7da418f49468da4abab8a80
http://doc.rero.ch/record/298145/files/cis611.pdf
http://doc.rero.ch/record/298145/files/cis611.pdf
Publikováno v:
Molecular Pharmacology. 54:1097-1105
Wild-type alpha1beta2gamma2 gamma-aminobutyric acid (GABA)A receptors and receptors containing a point-mutated subunit gamma2F77Y were expressed by transient transfection in human embryonic kidney 293 cells. Mutant receptors bound the benzodiazepine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddea9f7c9ddfbc3be01edb00c6002d64
https://doi.org/10.1124/mol.54.6.1097
https://doi.org/10.1124/mol.54.6.1097
Publikováno v:
Molecular Pharmacology. 52:676-682
Ligands of the benzodiazepine binding site allosterically modulate gamma-aminobutyric acidA receptors. Their binding pocket is made up of amino acid residues located on both alpha and gamma subunits. We transiently expressed wild-type alpha1beta2gamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf471fe99b87de5350ec8c70758cc13
https://doi.org/10.1124/mol.52.4.676
https://doi.org/10.1124/mol.52.4.676
Autor:
Patricia Schlagenhauf, Miriam Adamcova, Iain Cockburn, Martin T. Schaerer, Isabella Bercaru, Hans-Georg Rhein
Publikováno v:
Travel medicine and infectious disease. 13(5)
Summary Background Between 80 and 90 million travellers visit malaria endemic areas annually and many require malaria chemoprophylaxis. The characterization of the risk and nature of eye disorders occurring during the use of malaria chemoprophylaxis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6e15886418969eaf7839350ed8ed98b
https://pubmed.ncbi.nlm.nih.gov/26119539
https://pubmed.ncbi.nlm.nih.gov/26119539
Autor:
William A. Blumentals, Loredana Regep, Pia Suter, Hans-Georg Rhein, Margarita Suarez Boutros, Martin T. Schaerer, Miriam Adamcova, Patricia Schlagenhauf, Gabriel Vital-Durand
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Pregnant women who travel to malarious areas and their clinicians need data on the safety of malaria chemoprophylaxis. The drug safety database analysis of mefloquine exposure in pregnancy showed that the birth defect prevalence and fetal loss in mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01820bee92e757267f7f7db3e7e5e8a7
https://pubmed.ncbi.nlm.nih.gov/22761410
https://pubmed.ncbi.nlm.nih.gov/22761410
Autor:
Martin T. Schaerer, Miriam Adamcova, Loredana Regep, Patricia Schlagenhauf, Sudhir Bansod, Hans-Georg Rhein
Publikováno v:
Malaria Journal
Malaria Journal, Vol 10, Iss 1, p 292 (2011)
Malaria Journal, Vol 10, Iss 1, p 292 (2011)
Background Use of anti-malarial medication in children is hampered by a paucity of dosage, pharmacokinetic and tolerability data. Methods Data on the use of mefloquine in children, particularly in young children weighing less than 20 kg, were reviewe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11df45801a453e40939322fbc3e94562
https://doi.org/10.1186/1475-2875-10-292
https://doi.org/10.1186/1475-2875-10-292
Publikováno v:
Malaria Journal, Vol 9, Iss 1, p 357 (2010)
Malaria Journal
Malaria Journal
Background Malaria chemoprophylaxis prevents the occurrence of the symptoms of malaria. Travellers to high-risk Plasmodium falciparum endemic areas need an effective chemoprophylaxis. Methods A literature search to update the status of mefloquine as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ee37f07e62d204c851f9f84856f4bc
Autor:
Lie Chen, Zen H. Lu, Lilianne Kappeler, Joachim Weis, Franziska Joncourt, Doris Lang, Martin T. Schaerer, Sabina Gallati, Jean-Marc Burgunder, Juerg Fritschi, Erwin Sigel
Publikováno v:
Musclenerve. 29(5)
Mutations in CLCN1, the gene encoding the ClC-1 chloride channel in skeletal muscle, lead to myotonia congenita. The effects on the intramembranous channel forming domains have been investigated more than that at the intracellular C-terminus. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716323dcd8850de16e82e18f95f078cd
https://pubmed.ncbi.nlm.nih.gov/15116370
https://pubmed.ncbi.nlm.nih.gov/15116370
Publikováno v:
The Journal of biological chemistry. 276(28)
gamma-Aminobutyric acid type A (GABA(A)) receptors were immunopurified from bovine brain using a monoclonal antibody directed against the alpha1 subunit. Of the several proteins that copurified, a 34-kDa protein was analyzed further. After enrichment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ddfb1880621d95f4501db6fa7964600
https://pubmed.ncbi.nlm.nih.gov/11350968
https://pubmed.ncbi.nlm.nih.gov/11350968
Publikováno v:
The Journal of biological chemistry. 274(30)
Tuning of gamma-aminobutyric acid type A (GABA(A)) receptor function via phosphorylation of the receptor potentially allows neurons to modulate their inhibitory input. Several kinases, both of the serine-threonine kinase and the tyrosine kinase famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b9188b01166556b5075bbc6ed3fdab
https://pubmed.ncbi.nlm.nih.gov/10409683
https://pubmed.ncbi.nlm.nih.gov/10409683