Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Martin Szyska"'
Autor:
Adriane Halik, Marlon Tilgner, Patricia Silva, Natalia Estrada, Robert Altwasser, Ekaterina Jahn, Michael Heuser, Hsin-An Hou, Marta Pratcorona, Robert K. Hills, Klaus H. Metzeler, Laurene Fenwarth, Anna Dolnik, Christine Terre, Klara Kopp, Olga Blau, Martin Szyska, Friederike Christen, Jan Krönke, Loïc Vasseur, Bob Löwenberg, Jordi Esteve, Peter J. M. Valk, Matthieu Duchmann, Wen-Chien Chou, David C. Linch, Hartmut Döhner, Rosemary E. Gale, Konstanze Döhner, Lars Bullinger, Kenichi Yoshida, Frederik Damm
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract Background Deletions and partial losses of chromosome 7 (chr7) are frequent in acute myeloid leukemia (AML) and are linked to dismal outcome. However, the genomic landscape and prognostic impact of concomitant genetic aberrations remain inco
Externí odkaz:
https://doaj.org/article/c4bde76aa3284c6f887bca011315517d
Autor:
David Wong, Oliver Winter, Christina Hartig, Svenja Siebels, Martin Szyska, Benjamin Tiburzy, Lingzhang Meng, Upasana Kulkarni, Anke Fähnrich, Kurt Bommert, Ralf Bargou, Claudia Berek, Van Trung Chu, Bjarne Bogen, Franziska Jundt, Rudolf Armin Manz
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109018 (2014)
Multiple myeloma is a bone marrow plasma cell tumor which is supported by the external growth factors APRIL and IL-6, among others. Recently, we identified eosinophils and megakaryocytes to be functional components of the micro-environmental niches o
Externí odkaz:
https://doaj.org/article/3dac5a1d303f4274bb3f665f97434656
Autor:
Benjamin Tiburzy, Martin Szyska, Hiroaki Iwata, Navina Chrobok, Upasana Kulkarni, Misa Hirose, Ralf J Ludwig, Kathrin Kalies, Jürgen Westermann, David Wong, Rudolf Armin Manz
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83631 (2013)
Autoantibodies are believed to be maintained by either the continuous generation of short-lived plasma cells in secondary lymphoid tissues or by long-lived plasma cells localized in bone marrow and spleen. Here, we show in a mouse model for the autoi
Externí odkaz:
https://doaj.org/article/b69bedf208664ce085a7c7d464091d60
Autor:
Il-Kang Na, Thomas Blankenstein, Bernd Dörken, Isabell Durieux, Tra My Dang, Daniele D'Abundo, Josefine Russ, Andreas Heimann, Stefanie Althoff, Stefanie Herda, Martin Szyska
Figure S1 - The NFAT-CBR reporter reveals systemic alloreactivity in a major mismatch model. Figure S2 - The NFAT-CBR reporter in response to specific antigen. Figure S3 - Homeostatic expansion of BLITC T cells in in vivo. Figure S4 - CRISPR-Cas9 med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d003aac6b066f4c84441a7270c0b5a95
https://doi.org/10.1158/2326-6066.22539937
https://doi.org/10.1158/2326-6066.22539937
Autor:
Il-Kang Na, Thomas Blankenstein, Bernd Dörken, Isabell Durieux, Tra My Dang, Daniele D'Abundo, Josefine Russ, Andreas Heimann, Stefanie Althoff, Stefanie Herda, Martin Szyska
Adoptive T-cell therapy (ATT) efficacy is limited when targeting large solid tumors. The evaluation of ATT outcomes using accessory treatment would greatly benefit from an in vivo monitoring tool, allowing the detection of functional parameters of tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e395f90058437cc7ac2bbf1db37343
https://doi.org/10.1158/2326-6066.c.6549232.v1
https://doi.org/10.1158/2326-6066.c.6549232.v1
Autor:
Lars Bullinger, Bernhard Gillissen, Eva M. Kaebisch, Andreas Thiel, Lisa I Olfe, Youngseong Oh, Petra Reinke, Il-Kang Na, Sonya C. Becker, Martin Szyska, Hans-Dieter Volk, Mi-Young Cho
Publikováno v:
Transplantation. 103:2234-2244
Background Graft-versus-host disease (GvHD) presents a major cause for morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Rabbit-derived antithymocyte globulin (rATG) treatment reduces the incidence of GvHD after alloge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772e8f45fc70a741655f664b0bd50eb8
https://doi.org/10.1097/tp.0000000000002799
https://doi.org/10.1097/tp.0000000000002799
Autor:
Miriam Kull, Dirk Heckl, Martin Szyska, Denise Miller, Stephan R. Bohl, Lars Bullinger, Imke Bauhuf, Frederik Damm, Anthony Letai, Sarah Knödler, Christian Langer, Tamara J. Blätte, Jan Krönke, Anna Dolnik, Linda Röhner, Tatjana Meyer, Hartmut Döhner, Laura K. Schmalbrock
Publikováno v:
Blood Adv
The introduction of new drugs in the past years has substantially improved outcome in multiple myeloma (MM). However, the majority of patients eventually relapse and become resistant to one or multiple drugs. While the genetic landscape of relapsed/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff271f4d3ef187b966ad9604b2af991
https://pubmed.ncbi.nlm.nih.gov/33950175
https://pubmed.ncbi.nlm.nih.gov/33950175
Autor:
Tra My Dang, Martin Szyska, Thomas Blankenstein, Isabell Durieux, Stefanie Herda, Daniele D'Abundo, Andreas Heimann, Bernd Dörken, Il-Kang Na, Stefanie Althoff, Josefine Russ
Publikováno v:
Cancer immunology research. 6(1)
Adoptive T-cell therapy (ATT) efficacy is limited when targeting large solid tumors. The evaluation of ATT outcomes using accessory treatment would greatly benefit from an in vivo monitoring tool, allowing the detection of functional parameters of tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a7b2e118983b4df7b3751cdc111f09
https://pubmed.ncbi.nlm.nih.gov/29259004
https://pubmed.ncbi.nlm.nih.gov/29259004
Publikováno v:
Arthritis & Rheumatism. 64:1237-1246
Objective Autoantibody immune complexes and cellular infiltrates drive nephritis in patients with systemic lupus erythematosus (SLE) and in murine lupus. The chemokine receptor CXCR3 is assumed to promote cellular infiltration of inflamed tissues. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc43b4a86327f6c7f8cf0677e73c598d
https://doi.org/10.1002/art.33424
https://doi.org/10.1002/art.33424
Autor:
Oliver Winter, Henriette Kaminski, Martin Szyska, Christof Dame, Rudolf A. Manz, Dimitra Zotos, David M. Tarlinton, Harald Schulze, Elodie Mohr, David M. Wong, Katrin Roth, Ian C. M. MacLennan, Katrin Moser
Publikováno v:
Blood. 116:1867-1875
Long-lived plasma cells in the bone marrow produce memory antibodies that provide immune protection persisting for decades after infection or vaccination but can also contribute to autoimmune and allergic diseases. However, the composition of the mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98a87c9af1a0b85a37b67e9862c9e260
https://doi.org/10.1182/blood-2009-12-259457
https://doi.org/10.1182/blood-2009-12-259457