Mechanism-based inhibition of human persulfide dioxygenase by γ-glutamyl-homocysteinyl-glycine

Autor: Javier Seravalli, Omer Kabil, Martin Strack, Ruma Banerjee, Nils Metzler-Nolte, Nicole Motl

Publikováno v: The Journal of biological chemistry. 293(32)

Hydrogen sulfide (H(2)S) is a signaling molecule with many beneficial effects. However, its cellular concentration is strictly regulated to avoid toxicity. Persulfide dioxygenase (PDO or ETHE1) is a mononuclear non-heme iron–containing protein in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6aa5646a97d262403180e32e806138
https://pubmed.ncbi.nlm.nih.gov/29980601

Urotensin core mimics that modulate the biological activity of urotensin-II related peptide but not urotensin-II

Autor: David Chatenet, Martin Strack, Etienne Billard, William D. Lubell

Publikováno v: Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2017, 27 (15), pp.3412-3416. ⟨10.1016/j.bmcl.2017.05.088⟩

International audience; A novel approach for the synthesis of head-to-tail cyclic peptides has been developed and used to prepare two mimics of the urotensin II-related peptide (URP) cyclic core. Mimics 1 and 2 (c[Trp-Lys-Tyr-Gly-ψ(triazole)-Gly] an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bab435f68b48b4530577cdf160e156c2
https://hal-riip.archives-ouvertes.fr/pasteur-01574618

A Blocking Group Scan Using a Spherical Organometallic Complex Identifies an Unprecedented Binding Mode with Potent Activity In Vitro and In Vivo for the Opioid Peptide Dermorphin

Autor: King Tuo Yip, Daniel Siegmund, Andrea Bedini, Nils Metzler-Nolte, Raphael Stoll, Sara Lombardi, Martin Strack, Santi Spampinato

Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 22(41)

Herein, the selective enforcement of one particular receptor-ligand interaction between specific domains of the μ-selective opioid peptide dermorphin and the μ opioid receptor is presented. For this, a blocking group scan is described which exploit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f47a46dcfa98c9d874b7a77897b34b
https://pubmed.ncbi.nlm.nih.gov/27553294

Predicting Wind Speed for Wind Energy; Progress of the WINDENG Project

Autor: Bengt Tammelin, Martin Strack, Silke Dierer, A. Lavagnini, Francesco Durante, Bernhard Lange, Erik Gregow, Tim de Paus

Publikováno v: 29 (2005): 393-40.
info:cnr-pdr/source/autori:Dierer,S., T.de Paus, F. Durante, E. Gregow, B. Lange, A.Lavagnini, M. Strack and B.Tammelin/titolo:Predicting Wind Speed for Wind Energy; Progress of the WINDENG Project/doi:/rivista:/anno:2005/pagina_da:393-40/pagina_a:/intervallo_pagine:393-40/volume:29

The suitability of the computer model MM5 for predicting wind speed, and hence wind energy, is investigated by performing simulations for different geographical regions. The focus is on wind speed in the lowest 200 m of the planetary boundary layer (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65019703ed60fe32efabaa1771b757cc
https://doi.org/10.1260/030952405775992616

FTIR spectroscopy of cysteine as a ready-to-use method for the investigation of plasma-induced chemical modifications of macromolecules

Autor: Sabrina Baldus, Jan-Wilm Lackmann, Nils Metzler-Nolte, Martina Havenith, Konstantin Kartaschew, Martin Strack, Peter Awakowicz, Friederike Kogelheide, Katharina Stapelmann

Publikováno v: Journal of Physics D: Applied Physics. 49:084004

A rapid screening method for the investigation of plasma-induced chemical modifications was developed by analyzing cysteine using Fourier Transform Infrared (FTIR) spectroscopy. Cysteine is a key amino acid in proteins due to the presence of a thiol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd9a4e2486e3d6ff11c6a8df7ca33d3f
https://doi.org/10.1088/0022-3727/49/8/084004