Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Martin Stehling"'
Autor:
Jonas Stewen, Kai Kruse, Anca T. Godoi-Filip, Zenia, Hyun-Woo Jeong, Susanne Adams, Frank Berkenfeld, Martin Stehling, Kristy Red-Horse, Ralf H. Adams, Mara E. Pitulescu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Cell segregation allows the compartmentalization of cells with similar fates during morphogenesis, which can be enhanced by cell fate plasticity in response to local molecular and biomechanical cues. Endothelial tip cells in the growing reti
Externí odkaz:
https://doaj.org/article/faab32200a734a3cb94bf3c9b2e26b8f
Autor:
Lampros Mavrommatis, Hyun-Woo Jeong, Urs Kindler, Gemma Gomez-Giro, Marie-Cecile Kienitz, Martin Stehling, Olympia E Psathaki, Dagmar Zeuschner, M Gabriele Bixel, Dong Han, Gabriela Morosan-Puopolo, Daniela Gerovska, Ji Hun Yang, Jeong Beom Kim, Marcos J Arauzo-Bravo, Jens C Schwamborn, Stephan A Hahn, Ralf H Adams, Hans R Schöler, Matthias Vorgerd, Beate Brand-Saberi, Holm Zaehres
Publikováno v:
eLife, Vol 12 (2023)
In vitro culture systems that structurally model human myogenesis and promote PAX7+ myogenic progenitor maturation have not been established. Here we report that human skeletal muscle organoids can be differentiated from induced pluripotent stem cell
Externí odkaz:
https://doaj.org/article/2882c4b7b3864986853c1bc24996070e
Autor:
Yang Liu, Qi Chen, Hyun-Woo Jeong, Bong Ihn Koh, Emma C. Watson, Cong Xu, Martin Stehling, Bin Zhou, Ralf H. Adams
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The colonization of bone marrow by haematopoietic stem and progenitor cells is critical for lifelong blood cell formation. Here the authors report distinct features of fetal bone marrow and show that artery-derived signals promote haematopoietic colo
Externí odkaz:
https://doaj.org/article/cbd059c3da144a1faae8a9b2837738b6
Autor:
Binyamin Duethorn, Fabian Groll, Bettina Rieger, Hannes C. A. Drexler, Heike Brinkmann, Ludmila Kremer, Martin Stehling, Marie-Theres Borowski, Karina Mildner, Dagmar Zeuschner, Magdalena Zernicka-Goetz, Marc P. Stemmler, Karin B. Busch, Juan M. Vaquerizas, Ivan Bedzhov
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
How pluripotency transcription factors regulate the cellular architecture and energetics has remained largely unknown. Here the authors identify Lima1 as a key effector that mediates the pluripotency control of membrane dynamics and cellular metaboli
Externí odkaz:
https://doaj.org/article/ec59b98c93f041c9b516251c4f4d904c
Autor:
Swetha Raghuraman, Ann‐Sophie Schubert, Stephan Bröker, Alejandro Jurado, Annika Müller, Matthias Brandt, Bart E. Vos, Arne D. Hofemeier, Fatemeh Abbasi, Martin Stehling, Raphael Wittkowski, Johanna Ivaska, Timo Betz
Publikováno v:
Advanced Science, Vol 9, Iss 6, Pp n/a-n/a (2022)
Abstract A key behavior observed during morphogenesis, wound healing, and cancer invasion is that of collective and coordinated cellular motion. Hence, understanding the different aspects of such coordinated migration is fundamental for describing an
Externí odkaz:
https://doaj.org/article/143b9e3ffa30476288aac2cd806bdd8c
Autor:
Cong Xu, Van Vuong Dinh, Kai Kruse, Hyun-Woo Jeong, Emma C Watson, Susanne Adams, Frank Berkenfeld, Martin Stehling, Seyed Javad Rasouli, Rui Fan, Rui Chen, Ivan Bedzhov, Qi Chen, Katsuhiro Kato, Mara E Pitulescu, Ralf H Adams
Publikováno v:
eLife, Vol 11 (2022)
Declining bone mass is associated with aging and osteoporosis, a disease characterized by progressive weakening of the skeleton and increased fracture incidence. Growth and lifelong homeostasis of bone rely on interactions between different cell type
Externí odkaz:
https://doaj.org/article/ebbaa7ce6ecc46b4b0f5118aa202fcd6
Autor:
Guangxia Wang, Lars Muhl, Yvonne Padberg, Laura Dupont, Josi Peterson-Maduro, Martin Stehling, Ferdinand le Noble, Alain Colige, Christer Betsholtz, Stefan Schulte-Merker, Andreas van Impel
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
How and where VEGF-C is processed in lymphangiogenesis is unclear. Here, the authors show that development of the zebrafish lymphatic system is locally restricted by Vegfc maturation causing lymphatic sprouting in certain regions, which is regulated
Externí odkaz:
https://doaj.org/article/7d9c7602b7f54a6bbd0b0e6fd9867d83
Autor:
Ksenia Skvortsova, Katsiaryna Tarbashevich, Martin Stehling, Ryan Lister, Manuel Irimia, Erez Raz, Ozren Bogdanovic
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Germ cells are the means of transferring genetic information to the next generation. Here the authors characterise the DNA methylomes of zebrafish primordial germ cells and find that, unlike mammals, the zebrafish germ cells do not undergo genome-wid
Externí odkaz:
https://doaj.org/article/f5ad45bf28cb41f8a8d95e38f494f2dc
Autor:
Lydia Reinhardt, Susanne Kordes, Peter Reinhardt, Michael Glatza, Matthias Baumann, Hannes C.A. Drexler, Sascha Menninger, Gunther Zischinsky, Jan Eickhoff, Claudia Fröb, Prabesh Bhattarai, Guruchandar Arulmozhivarman, Lara Marrone, Antje Janosch, Kenjiro Adachi, Martin Stehling, Eric N. Anderson, Masin Abo-Rady, Marc Bickle, Udai Bhan Pandey, Michell M. Reimer, Caghan Kizil, Hans R. Schöler, Peter Nussbaumer, Bert Klebl, Jared L. Sterneckert
Publikováno v:
Stem Cell Reports, Vol 12, Iss 3, Pp 502-517 (2019)
Summary: Neuroinflammation is a hallmark of neurological disorders and is accompanied by the production of neurotoxic agents such as nitric oxide. We used stem cell-based phenotypic screening and identified small molecules that directly protected neu
Externí odkaz:
https://doaj.org/article/d6324808720f45358bb83abf2c104f0a
Autor:
Katsuhiro Kato, Rodrigo Diéguez-Hurtado, Do Young Park, Seon Pyo Hong, Sakiko Kato-Azuma, Susanne Adams, Martin Stehling, Britta Trappmann, Jeffrey L. Wrana, Gou Young Koh, Ralf H. Adams
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Pericytes surround endothelial tubules and help maintain the integrity of blood vessels. Here the authors show that pericytes regulate lung morphogenesis via paracrine signalling controlled by components of the Hippo pathway.
Externí odkaz:
https://doaj.org/article/a1d83014331540c8b3d754cb9ea4c153