Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Martin Sima"'
Autor:
Alena Pilkova, Martin Sima, Jan Miroslav Hartinger, Thi Minh Phuong Nikrynova Nguyen, Vera Maresova, Ivana Kurcova, Ondrej Slanar, Jiri Widimsky
Publikováno v:
Biomedical Papers, Vol 168, Iss 2, Pp 117-123 (2024)
Aim. The aim of this study was to evaluate adherence to spironolactone in a group of unselected patients with arterial hypertension by analysis of measured serum spironolactone and canrenone concentrations according to a proposed two-step decision sc
Externí odkaz:
https://doaj.org/article/e0f34d8d416c4a96a5096718085a2448
Publikováno v:
Biomedical Papers, Vol 168, Iss 1, Pp 81-84 (2024)
Background. Continuous caudal epidural analgesia used intraoperatively in children is an effective and safe technique. However, in preterm neonates, developmental factors may significantly affect levobupivacaine disposition, leading to variable pharm
Externí odkaz:
https://doaj.org/article/d5e1f0c96ecc48d39fb033097aa94ade
Publikováno v:
Biomedical Papers, Vol 167, Iss 2, Pp 208-211 (2023)
Aims. The aim of this pharmacokinetic study was to describe and quantify population pharmacokinetics of three antibiotics, cefazolin, ampicillin, and ciprofloxacin, used as antibacterial prophylaxis during cardiovascular surgery with the use of extra
Externí odkaz:
https://doaj.org/article/403b053f718d4782b6af585802a3c5f2
Autor:
Danica Michalickova, Ivana Kramarikova, Hatice Kubra Ozturk, Tomas Kucera, Tomas Vacik, Tomas Hrncir, Nikolina Kutinova Canova, Martin Sima, Ondrej Slanar
Publikováno v:
Biomedical Papers, Vol 167, Iss 1, Pp 36-42 (2023)
Aims. The neuropeptide galanin is a widely distributed neurotransmitter/neuromodulator that regulates a variety of physiological processes and also participates in the regulation of stress responses. The aims of the present study were to investigate
Externí odkaz:
https://doaj.org/article/2e6aea668cdb4f4c9c0cd40e20507bb5
Autor:
Olga Bartosova, Martin Sima, Ondrej Polanecky, Frantisek Perlik, Svatopluk Adamek, Robert Lischke, Ondrej Slanar
Publikováno v:
Biomedical Papers, Vol 166, Iss 1, Pp 40-45 (2022)
Aims. The aim of this study was to compare the efficacy, consumption and safety after piritramide administered either intramuscularly (IM) on demand or via patient-controlled intravenous analgesia (PCA) and to examine the impact of OPRM1 and ABCB1 ge
Externí odkaz:
https://doaj.org/article/be6a99455fdd44c4a2b27e24b4c8e023
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 15, Iss 1 (2022)
Background: P. aeruginosa sepsis in immunocompromised patients is serious complication of cancer treatment, especially in case of XDR pathogen. The purpose of the study is to evaluate the efficacy of high-dose ceftazidime in treatment of XDR P. ae
Externí odkaz:
https://doaj.org/article/8d138b8039c44d728f49059b0e541a22
Autor:
Martina Kodetova, Radka Hobzova, Jakub Sirc, Jiri Uhlik, Katerina Dunovska, Karel Svojgr, Ana-Irina Cocarta, Andrea Felsoova, Ondrej Slanar, Martin Sima, Igor Kozak, Pavel Pochop
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 903 (2022)
Transscleral diffusion delivery of chemotherapy is a promising way to reach the vitreal seeds of retinoblastoma, the most common intraocular malignancy in childhood. In this in vivo study, the delivery of topotecan via lens-shaped, bi-layered hydroge
Externí odkaz:
https://doaj.org/article/fc0f868ff3e84f848de771bd01a89f3f
Autor:
Jan SIPEK, Pavla POKORNA, Martin SIMA, Ivan BERKA, Tomas HLOZEK, Jitka STYBLOVA, Vladimir MIXA, Barbora NEDOMOVA
Publikováno v:
Bratislava Medical Journal. 124:116-120
Differences in neonatal pharmacokinetics are known to cause systemic accumulation of levobupivacaine with adverse effects during epidural analgesia. Therefore, it is not recommended to surpass 48 hours of administration in neonates. Free and total le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab4b6bb89082413c913175aa33bb89a
https://doi.org/10.4149/bll_2023_018
https://doi.org/10.4149/bll_2023_018
Autor:
Alzbeta Zavrelova, Martin Sima, Jana Malakova, Petra Rozsivalova, Pavla Paterova, Pavel Zak, Benjamin Visek, Danica Michalickova, Ondrej Slanar, Jakub Radocha
Publikováno v:
British Journal of Clinical Pharmacology. 89:1452-1461
The objective of this study was to evaluate off-label high-dose ceftazidime population pharmacokinetics in cancer patients with suspected or proven extensively drug resistant (XDR) Pseudomonas aeruginosa infections, and then to compare the achievemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36984dfe5dc821044f6f02249426717a
https://doi.org/10.1111/bcp.15612
https://doi.org/10.1111/bcp.15612
Autor:
Émilie Saulnier-Talbot, Éliane Duchesne, Dermot Antoniades, Dominique Arseneault, Christine Barnard, Dominique Berteaux, Najat Bhiry, Frédéric Bouchard, Stéphane Boudreau, Kevin Cazelles, Jérôme Comte, Madeleine-Zoé Corbeil-Robitaille, Steeve D. Côté, Raoul-Marie Couture, Guillaume de Lafontaine, Florent Domine, Dominique Fauteux, Daniel Fortier, Michelle Garneau, Gilles Gauthier, Dominique Gravel, Isabelle Laurion, Martin Lavoie, Nicolas Lecomte, Pierre Legagneux, Esther Lévesque, Marie-José Naud, Michel Paquette, Serge Payette, Reinhard Pienitz, Milla Rautio, Alexandre Roy, Alain Royer, Martin Simard, Warwick F. Vincent, Joël Bêty
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-15 (2024)
Abstract Northern regions are warming faster than the rest of the globe. It is difficult to predict ecosystem responses to warming because the thermal sensitivity of their biophysical components varies. Here, we present an analysis of the authors’
Externí odkaz:
https://doaj.org/article/62b0154e86ce4b5d8d8c6e86fd3c6fd8