Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1

Autor: Martin Senitko, Pamela D. Winterberg, Xin J. Zhou, Colin J. Meyer, Qingqing Wu, Jianlin Chen, Yanxia Wang, John R. Hartono, Deborah A. Ferguson, Bo Chen, Anapam Agarwal, Christopher Y. Lu, W. Christian Wigley, Eric Ben Grossman

Publikováno v: American Journal of Physiology-Renal Physiology. 300:F1180-F1192

Ischemic acute kidney injury (AKI) triggers expression of adaptive (protective) and maladaptive genes. Agents that increase expression of protective genes should provide a therapeutic benefit. We now report that bardoxolone methyl (BARD) ameliorates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96bf8e4ad521f4526e7e67761ab7b49
https://doi.org/10.1152/ajprenal.00353.2010

The inflammatory response to ischemic acute kidney injury: a result of the ‘right stuff’ in the ‘wrong place’?

Autor: Jianlin Chen, Martin Senitko, John R. Hartono, Christopher Y. Lu

Publikováno v: Current Opinion in Nephrology and Hypertension. 16:83-89

Purpose of review Ischemic acute kidney injury may be exacerbated by an inflammatory response. How injury elicits inflammation remains a major question in understanding acute kidney injury. The present review examines the hypothesis that molecules re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b526aec7096c3522640752e58070c6fe
https://doi.org/10.1097/mnh.0b013e3280403c4e

Contributors

Autor: MAURO ABBATE, DALE R. ABRAHAMSON, MARCIN ADAMCZAK, HORACIO J. ADROGUÉ, SETH L. ALPER, ROBERT J. ALPERN, THOMAS E. ANDREOLI, ANITA C. APERIA, MATTHEW A. BAILEY, DANIEL BATLLE, MICHEL BAUM, THERESA J. BERNDT, MARK O. BEVENSEE, JÜRG BIBER, DANIEL G. BICHET, RENÉ J.M. BINDELS, ROLAND C. BLANTZ, WALTER F. BORON, D. CRAIG BRATER, JOSEPHINE P. BRIGGS, ALEX BROWN, NIGEL J. BRUNSKILL, GERHARD BURCKHARDT, GEOFFREY BURNSTOCK, LLOYD CANTLEY, CHUNHUA CAO, GIOVAMBATTISTA CAPASSO, MICHAEL J. CAPLAN, HUGH J. CARROLL, LAURENCE CHAN, MOONJA CHUNG-PARK, FREDRIC L. COE, THOMAS M. COFFMAN, WAYNE D. COMPER, KIRK P. CONRAD, STEVEN D. CROWLEY, NORMAN P. CURTHOYS, PEDRO R. CUTILLAS, THEODORE M. DANOFF, EDWARD S. DEBNAM, HENRIK DIMKE, ALAIN DOUCET, RAGHVENDRA K. DUBEY, ADRIANA DUSSO, KAI-UWE ECKARDT, DAVID H. ELLISON, HITOSHI ENDOU, ZOLTÁN HUBA ENDRE, FRANKLIN H. EPSTEIN, ANDREW EVAN, RONALD J. FALK, KAMBIZ FARBAKHSH, NICHOLAS R. FERRERI, PEYING FONG, MANASSES CLAUDINO FONTELES, IAN FORSTER, LEONARD RALPH FORTE, HAROLD A. FRANCH, LYNDA A. FRASSETTO, PETER A. FRIEDMAN, JØRGEN FRØKLÆR, JOHN P. GEIBEL, MICHAEL GEKLE, GERHARD GIEBISCH, PERE GINÈS, STEVE A.N. GOLDSTEIN, SIMIN GORAL, SIAN V. GRIFFIN, WILLIAM B. GUGGINO, THERESA A. GUISE, SUSAN B. GURLEY, STEPHEN D. HALL, MITCHELL L. HALPERIN, L. LEE HAMM, STEVEN C. HEBERT, MATTHIAS A. HEDIGER, J. HAROLD HELDERMAN, WILLIAM L. HENRICH, AILLEEN HERAS-HERZIG, NATI HERNANDO, JOOST G.J. HOENDEROP, ULLA HOLTBÄCK, JEAN-DANIEL HORISBERGER, EDITH HUMMLER, TRACY E. HUNLEY, EDWIN K. JACKSON, J. CHARLES JENNETTE, EDWARD J. JOHNS, JOHN P. JOHNSON, BRIGITTE KAISSLING, KAMEL S. KAMEL, S. ANANTH KARUMANCHI, CLIFFORD E. KASHTAN, BERTRAM L. KASISKE, ADRIAN I. KATZ, BRIAN F. KING, SAULO KLAHR, THOMAS R. KLEYMAN, HERMANN KOEPSELL, VALENTINA KON, MARTIN KONRAD, ULLA C. KOPP, RETO KRAPF, WILHELM KRIZ, RAJIV KUMAR, CHRISTINE E. KURSCHAT, ARMIN KURTZ, TAE-HWAN KWON, CHRISTOPHER P. LANDOWSKI, ANTHONY J. LANGONE, FLORIAN LANG, HAROLD E. LAYTON, THU H. LE, DANIEL I. LEVY, SHIH-HUA LIN, MARSHALL D. LINDHEIMER, CHRISTOPHER Y. LU, MICHAEL P. MADAIO, NICOLAOS E. MADIAS, GERHARD MALNIC, KARL S. MATLIN, WILLIAM C. McCLELLAN, JOHN C. MCGIFF, C. CHARLES MICHEL, JEFFREY H. MINER, WILLIAM E. MITCH, HIROKI MIYAZAKI, ORSON W. MOE, BRUCE A. MOLITORIS, R. CURTIS MORRIS, SALIM K. MUJAIS, HEINI MURER, SHIGEAKI MUTO, EUGENE NATTIE, ERIC G. NEILSON, SØREN NIELSEN, SANJAY K. NIGAM, JOSEPH M. NOGUEIRA, MAN S. OH, MARK D. OKUSA, TANYA M. OSICKA, THOMAS L. PALLONE, BIFF F. PALMER, LAWRENCE G. PALMER, MARK D. PARKER, JOAN H. PARKS, PATRICIA A. PREISIG, GARY A. QUAMME, L. DARRYL QUARLES, RAYMOND QUIGLEY, W. BRIAN REEVES, GIUSEPPE REMUZZI, LUIS REUSS, DANIELA RICCARDI, BRIAN RINGHOFER, EBERHARD RITZ, CHRISTOPHER J. RIVARD, GARY L. ROBERTSON, ROBERT M. ROSA, BERNARD C. ROSSIER, LEILEATA M. RUSSO, HENRY SACKIN, HIROYUKI SAKURAI, JEFF M. SANDS, LISA M. SATLIN, HEIDI SCHAEFER, JEFFREY R. SCHELLING, LAURENT SCHILD, KARL P. SCHLINGMANN, JÜRGEN B. SCHNERMANN, ROBERT W. SCHRIER, ANTHONY SEBASTIAN, JOHN R. SEDOR, YOAV SEGAL, TAKASHI SEKINE, DONALD W. SELDIN, MARTIN SENITKO, MALATHI SHAH, SUDHIR V. SHAH, STUART J. SHANKLAND, ASIF A. SHARFUDDIN, KUMAR SHARMA, SHAOHU SHENG, DAVID G. SHIRLEY, STEFAN SILBERNAGL, STEPHEN M. SILVER, MEL SILVERMAN, EDUARDO SLATOPOLSKY, STEFAN SOMLO, RICHARD H. STERNS, ANDREW K. STEWART, YOSHIRO SUZUKI, PETER J. TEBBEN, SCOTT C. THOMSON, VICENTE E. TORRES, ROBERT J. UNWIN, FRANÇOIS VERREY, DAVID L. VESELY, CARSTEN A. WAGNER, MERYL WALDMAN, ROBERT JAMES WALKER, WEI WANG, WEN-HUI WANG, YINGHONG WANG, ALAN M. WEINSTEIN, PAUL A. WELLING, GUNTER WOLF, ELAINE WORCESTER, FUAD N. ZIYADEH, CARLA ZOJA

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https://doi.org/10.1016/b978-012088488-9.50001-2

An update on renovascular hypertension

Autor: Martin Senitko, Andrew Z. Fenves

Publikováno v: Current cardiology reports. 7(6)

Renovascular hypertension (RVH) represents a secondary and potentially remediable form of hypertension. Elevated blood pressure is only one of a broad array of pathophysiologic consequences that are associated with decreased renal perfusion. Our abil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c01631ba628d9c4340e4716b5c2e8f
https://pubmed.ncbi.nlm.nih.gov/16256008