Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Martin Schmuck"'
Autor:
Michelle Guignet, Martin Schmuck, Danielle J. Harvey, Danh Nguyen, Donald Bruun, Angela Echeverri, Gene Gurkoff, Pamela J. Lein
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13449- (2023)
The field of cell biology has seen major advances in both cellular imaging modalities and the development of automated image analysis platforms that increase rigor, reproducibility, and throughput for large imaging data sets. However, there remains a
Externí odkaz:
https://doaj.org/article/9ba4d4a422c3426f9c9ab8e78480b2c1
Autor:
Laura Nimtz, Julia Hartmann, Julia Tigges, Stefan Masjosthusmann, Martin Schmuck, Eike Keßel, Stephan Theiss, Karl Köhrer, Patrick Petzsch, James Adjaye, Claudia Wigmann, Dagmar Wieczorek, Barbara Hildebrandt, Farina Bendt, Ulrike Hübenthal, Gabriele Brockerhoff, Ellen Fritsche
Publikováno v:
Stem Cell Research, Vol 45, Iss , Pp - (2020)
Neurotoxicity is mediated by a variety of modes-of-actions leading to disturbance of neuronal function. In order to screen larger numbers of compounds for their neurotoxic potential, in vitro functional neuronal networks (NN) might be helpful tools.
Externí odkaz:
https://doaj.org/article/6ce21a344da041f7ac23989029624edd
Autor:
Maxi Hofrichter, Laura Nimtz, Julia Tigges, Yaschar Kabiri, Friederike Schröter, Brigitte Royer-Pokora, Barbara Hildebrandt, Martin Schmuck, Alexey Epanchintsev, Stephan Theiss, James Adjaye, Jean-Marc Egly, Jean Krutmann, Ellen Fritsche
Publikováno v:
Stem Cell Research, Vol 25, Iss C, Pp 72-82 (2017)
Developmental neurotoxicity (DNT) testing performed in rats is resource-intensive (costs, time, animals) and bears the issue of species extrapolation. Thus, reliable alternative human-based approaches are needed for predicting neurodevelopmental toxi
Externí odkaz:
https://doaj.org/article/98ecb7605fe2410a96b658b6b4f7c456
Autor:
Sebastijan Kovačič, Bettina Schafzahl, Nadejda B. Matsko, Katharina Gruber, Martin Schmuck, Stefan Koller, Stefan A. Freunberger, Christian Slugovc
Publikováno v:
ACS Applied Energy Materials. 5:14381-14390
Autor:
Franziska Bursch, Martin Schmuck, Claudia Grothe, Susanne Petri, Anastasia Sarikidi, Regina Rumpel, Ekaterini Kefalakes, Miren Ettcheto
Publikováno v:
European Journal of Neuroscience. 50:3028-3045
We have previously shown that total knockout of fibroblast growth factor-2 (FGF-2) results in prolonged survival and improved motor performance in superoxide dismutase 1 (SOD1G93A ) mutant mice, the most widely used animal model of the fatal adult on
Autor:
Martin Schmuck, Boris Görg, Ellen Fritsche, Charlotte von Gall, Beryl Schwarz-Herzke, Marion Victor, Katharina Dach, Amira A. H. Ali, Benita Sahlender, Andreas Kremer, Shakila Mir
Publikováno v:
Brain Structure & Function
Brain Structure & Function, 224(1), 373-386. Springer-Verlag
Brain Structure & Function, 224(1), 373-386. Springer-Verlag
We demonstrate the impact of a disrupted molecular clock in Bmal1-deficient (Bmal1−/−) mice on migration of neural progenitor cells (NPCs). Proliferation of NPCs in rostral migratory stream (RMS) was reduced in Bmal1−/− mice, consistent with
Autor:
Franziska Bursch, Susanne Petri, Marta Barenys, Maximilian Naujock, Nancy Stanslowsky, Anastasia Sarikidi, Ekaterini Kefalakes, Miren Ettcheto, Claudia Grothe, Martin Schmuck, Florian Wegner, Sebastian Böselt
Publikováno v:
Journal of Cellular Physiology. 234:7395-7410
We have previously shown that knockout of fibroblast growth factor-2 (FGF-2) and potential compensatory effects of other growth factors result in amelioration of disease symptoms in a transgenic mouse model of amyotrophic lateral sclerosis (ALS). ALS
Autor:
Kelly M Morales, Dennis R. Carty, Katharina Dach, Bianca Yaghoobi, Pamela J. Lein, Martin Schmuck
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology, vol 167, iss 1
To screen the tens of thousands of chemicals for which no toxicity data currently exists, it is necessary to move from in vivo rodent models to alternative models, such as zebrafish. Here, we used dechorionated Tropical 5D wild-type zebrafish embryos
Autor:
Lauren Matelski, Martin Schmuck, Pamela J. Lein, Donald A. Bruun, Rhianna K. Morgan, Ana Cristina Grodzki
Publikováno v:
Neuromethods ISBN: 9781071616369
Chemical perturbation of the temporal or spatial aspects of axonal or dendritic growth is associated with neurobehavioral deficits in animal models, and structural changes in axons and dendrites are thought to contribute to clinical symptoms associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f71c620434c3268c4f257f9cfedec60
https://escholarship.org/uc/item/8j75f949
https://escholarship.org/uc/item/8j75f949
Autor:
Martin Schmuck
Die Frage nach der Bestimmung des Verhältnisses von Glaube und Wissen gehört noch immer zu den zentralen Fragen der Theologie und Religionsphilosophie. Auf diese Frage gibt Martin Schmuck eine Antwort, indem er die auf Erfahrung, common sense und P