Zobrazeno 1 - 10
of 436
pro vyhledávání: '"Martin Schäfer"'
Autor:
Bianca Schacherl, Kiara Maurer, Martin Schäfer, Yvonne Remde, Frank Geyer, Annika Fried, Steffen Alexander Happel, Martina Benešová-Schäfer
Publikováno v:
Frontiers in Nuclear Engineering, Vol 3 (2024)
Targeted alpha therapy (TαT) represents an emerging and cutting-edge treatment option for patients dealing with highly challenging metastatic cancer diseases. Critically, the limited supply of alpha-particle-emitting radionuclides, so-called alpha i
Externí odkaz:
https://doaj.org/article/9fcb4d9841b243b7b135adad652ad5ab
Autor:
Gregor P. Lotz, Achim Lutz, Meret Martin-Facklam, Andre Hansbauer, Eginhard Schick, Ekkehard Moessner, Michael Antony, Thomas Stuchly, Maria Viert, Ralf J. Hosse, Anne Freimoser-Grundschober, Christian Klein, Martin Schäfer, Mirko Ritter, Kay-Gunnar Stubenrauch
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
An appropriately designed pharmacokinetic (PK) assay that is sensitive for anti-drug antibody (ADA) impact on relevant exposure is an alternative strategy to understand the neutralizing potential of ADAs. However, guidance on how to develop such PK a
Externí odkaz:
https://doaj.org/article/18341a26efd34158ae91f7ef9c0ff3f2
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Herbivory-induced responses in plants are typical examples of phenotypic plasticity, and their evolution is thought to be driven by herbivory. However, direct evidence of the role of induced responses in plant adaptive evolution to herbivore
Externí odkaz:
https://doaj.org/article/eaa2473ed72d481899da25e307b6304d
Autor:
Hans Peter Grimm, Vanessa Schumacher, Martin Schäfer, Sabine Imhof-Jung, Per-Ola Freskgård, Kevin Brady, Carsten Hofmann, Petra Rüger, Tilman Schlothauer, Ulrich Göpfert, Maximilian Hartl, Sylvia Rottach, Adrian Zwick, Shanon Seger, Rachel Neff, Jens Niewoehner, Niels Janssen
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTThere are few treatments that slow neurodegeneration in Alzheimer’s disease (AD), and while therapeutic antibodies are being investigated in clinical trials for AD treatment, their access to the central nervous system is restricted by the b
Externí odkaz:
https://doaj.org/article/1e3d18094e0b44a99ca3a99a2f9d46b6
Autor:
Harun Taş, Gábor Bakos, Ulrike Bauder-Wüst, Martin Schäfer, Yvonne Remde, Mareike Roscher, Martina Benešová-Schäfer
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 513 (2024)
[177Lu]Lu-PSMA-617 has recently been successfully approved by the FDA, the MHRA, Health Canada and the EMA as Pluvicto®. However, salivary gland (SG) and kidney toxicities account for its main dose-limiting side-effects, while its corresponding upta
Externí odkaz:
https://doaj.org/article/9448b88781b44e8394308743e05b9eb9
Publikováno v:
Plants, Vol 13, Iss 6, p 845 (2024)
Understanding non-target-site resistance (NTSR) to herbicides represents a pressing challenge as NTSR is widespread in many weeds. Using giant duckweed (Spirodela polyrhiza) as a model, we systematically investigated genetic and molecular mechanisms
Externí odkaz:
https://doaj.org/article/74e09122552a41bd9126799d93232c89
Autor:
Katinka Albrecht, Hans-Peter Tony, Anja Strangfeld, Joern Kekow, Martin Schäfer, Yvette Meissner, Silke Zinke
Publikováno v:
RMD Open, Vol 9, Iss 4 (2023)
Objective To estimate the effects of Janus kinase inhibitors (JAKi), tumour necrosis factor inhibitors (TNFi), other biologic(b) or conventional synthetic(cs) disease-modifying antirheumatic drugs (DMARDs) on the risk of major adverse cardiovascular
Externí odkaz:
https://doaj.org/article/a12b1332d02044629ece91e4965e6012
Publikováno v:
Physics Letters B, Vol 844, Iss , Pp 138078- (2023)
We present the first five-body calculations of s-wave n-4He scattering within leading order and next-to-leading order (NLO) pionless effective field theory (π̸EFT). Using an harmonic oscillator trap technique and π̸EFT fitted to just six well-est
Externí odkaz:
https://doaj.org/article/5ed71a6844ed48aa9cc4999cadb2f970
Publikováno v:
Physics Letters B, Vol 840, Iss , Pp 137840- (2023)
We obtain the s- and p-wave low-energy scattering parameters for n3H elastic scattering and the position of the 4H Jπ=1− resonance using the pionless effective field theory at leading order. Results are extracted with three numerical techniques: c
Externí odkaz:
https://doaj.org/article/54334f9339184f01a6f0cd848bfd8c6e
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Background Positron emission tomography (PET) is a powerful tool in medical imaging, especially in combination with the PET radionuclide fluorine-18 that possesses optimal characteristics. For labelling of biomolecules and low-molecular weig
Externí odkaz:
https://doaj.org/article/97f7218c584545b0ae6eea319188fdf8