Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Martin Savko"'
1
Akademický článek
The crystal structure of iC3b-CR3 αI reveals a modular recognition of the main opsonin iC3b by the CR3 integrin receptor
Autor: Francisco J. Fernández, Jorge Santos-López, Rubén Martínez-Barricarte, Javier Querol-García, Héctor Martín-Merinero, Sergio Navas-Yuste, Martin Savko, William E. Shepard, Santiago Rodríguez de Córdoba, M. Cristina Vega
Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Complement activation on foreign cell surfaces leads to the generation of complement opsonins, which activate complement receptor type 3 (CR3) and pathogen clearance by macrophages. Here, the authors reveal structural basis of the interaction between
Externí odkaz: https://doaj.org/article/78117c6d84b049e588f1750afdba4664
Zobrazit plný text záznamu
2
Akademický článek
Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state
Autor: Jimena Rinaldi, Ignacio Fernández, Lucía M. Poth, William E. Shepard, Martin Savko, Fernando A. Goldbaum, Sebastián Klinke
Publikováno v: Biochemistry and Biophysics Reports, Vol 16, Iss , Pp 39-43 (2018)
The pathogenic bacterium Brucella abortus codes for a multi-domain dimeric cytoplasmic histidine kinase called LOV-HK, which is a key blue light-activated virulence factor in this microorganism. The structural basis of the light activation mechanism
Externí odkaz: https://doaj.org/article/8d53c9fbb12f4de780cc78a9626b4716
Zobrazit plný text záznamu
3
Akademický článek
Structural and Biochemical Analysis of OrfG: The VirB8-like Component of the Conjugative Type IV Secretion System of ICESt3 From Streptococcus thermophilus
Autor: Julien Cappele, Abbas Mohamad Ali, Nathalie Leblond-Bourget, Sandrine Mathiot, Tiphaine Dhalleine, Sophie Payot, Martin Savko, Claude Didierjean, Frédérique Favier, Badreddine Douzi
Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)
Conjugative transfer is a major threat to global health since it contributes to the spread of antibiotic resistance genes and virulence factors among commensal and pathogenic bacteria. To allow their transfer, mobile genetic elements including Integr
Externí odkaz: https://doaj.org/article/3ae34611d0bb417a89efcacc68e325f0
Zobrazit plný text záznamu
4
Akademický článek
Kilohertz Macromolecular Crystallography Using an EIGER Detector at Low X-ray Fluxes
Autor: Krishna P. Khakurel, Shirly Espinoza, Martin Savko, Vitaly Polovinkin, Jan Dohnalek, William Shepard, Angelina Angelova, Janos Hajdu, Jakob Andreasson, Borislav Angelov
Publikováno v: Crystals, Vol 10, Iss 12, p 1146 (2020)
Time-resolved in-house macromolecular crystallography is primarily limited by the capabilities of the in-house X-ray sources. These sources can only provide a time-averaged structure of the macromolecules. A significant effort has been made in the de
Externí odkaz: https://doaj.org/article/72eb84e2a21545119f84dfd322e38a4a
Zobrazit plný text záznamu
5
Akademický článek
The crystal structure and small-angle X-ray analysis of CsdL/TcdA reveal a new tRNA binding motif in the MoeB/E1 superfamily.
Autor: Miguel López-Estepa, Ana Ardá, Martin Savko, Adam Round, William E Shepard, Marta Bruix, Miquel Coll, Francisco J Fernández, Jesús Jiménez-Barbero, M Cristina Vega
Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0118606 (2015)
Cyclic N6-threonylcarbamoyladenosine ('cyclic t6A', ct(6)A) is a non-thiolated hypermodification found in transfer RNAs (tRNAs) in bacteria, protists, fungi and plants. In bacteria and yeast cells ct(6)A has been shown to enhance translation fidelity
Externí odkaz: https://doaj.org/article/55a12064588846e0973eaba05d7c41a1
Zobrazit plný text záznamu
7
Using Phaser and ensembles to improve the performance of SIMBAD
Autor: Jens M. H. Thomas, Martin Savko, Charles Ballard, Daniel J. Rigden, William Shepard, Marcin Wojdyr, Ronan M. Keegan, Andrey Lebedev, Felix Simkovic, Adam J. Simpkin, Ville Uski
Publikováno v: Acta Crystallographica. Section D, Structural Biology
Improvements to the sensitivity of the search for suitable molecular-replacement search models in SIMBAD through the use of Phaser and an ensemble-based model database are reported.
The conventional approach to search-model identification in mol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f681e8e6dc86eb41e68f9aac5caa9fd9
http://europepmc.org/articles/PMC6939438
Zobrazit plný text záznamu
8
Kilohertz Macromolecular Crystallography Using an EIGER Detector at Low X-ray Fluxes
Autor: Borislav Angelov, Vitaly Polovinkin, William Shepard, Shirly Espinoza, Janos Hajdu, Jan Dohnálek, Krishna P. Khakurel, Angelina Angelova, Martin Savko, Jakob Andreasson
Publikováno v: Crystals
Crystals, MDPI, 2020, 10 (12), pp.1146. ⟨10.3390/cryst10121146⟩
Crystals, Vol 10, Iss 1146, p 1146 (2020)
Volume 10
Issue 12
International audience; Time-resolved in-house macromolecular crystallography is primarily limited by the capabilities of the in-house X-ray sources. These sources can only provide a time-averaged structure of the macromolecules. A significant effort
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8ee986e05f9ba567c9d48c4f5a3e2a
https://hal.archives-ouvertes.fr/hal-03093546
Zobrazit plný text záznamu
10
Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state
Autor: Lucia Milagros Poth, William Shepard, Martin Savko, Sebastián Klinke, Jimena Rinaldi, Fernando Alberto Goldbaum, Ignacio Fernandez
Publikováno v: Biochemistry and Biophysics Reports, Vol 16, Iss, Pp 39-43 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Biochemistry and Biophysics Reports
The pathogenic bacterium Brucella abortus codes for a multi-domain dimeric cytoplasmic histidine kinase called LOV-HK, which is a key blue light-activated virulence factor in this microorganism. The structural basis of the light activation mechanism
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18cfe381c31d6840c2e1a19a16f45af3
https://www.sciencedirect.com/science/article/pii/S2405580818300955
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje