Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Martin Sauvageau"'
Autor:
Viviane Tran, Sarah Nahlé, Amélie Robert, Inès Desanlis, Ryan Killoran, Sophie Ehresmann, Marie-Pier Thibault, David Barford, Kodi S. Ravichandran, Martin Sauvageau, Matthew J. Smith, Marie Kmita, Jean-François Côté
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Myoblast fusion is essential for development of multinucleated myofibers. Here, the authors show that ablation of Elmo 1 and Elmo2 impairs myoblast fusion in mice, and that expression of an open conformation of Elmo2 promotes muscle regeneration and
Externí odkaz:
https://doaj.org/article/a22ad2614bc34d80b49198ec4a0a5ec3
Autor:
Jordan P. Lewandowski, Gabrijela Dumbović, Audrey R. Watson, Taeyoung Hwang, Emily Jacobs-Palmer, Nydia Chang, Christian Much, Kyle M. Turner, Christopher Kirby, Nimrod D. Rubinstein, Abigail F. Groff, Steve C. Liapis, Chiara Gerhardinger, Assaf Bester, Pier Paolo Pandolfi, John G. Clohessy, Hopi E. Hoekstra, Martin Sauvageau, John L. Rinn
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-35 (2020)
Abstract Background Several long noncoding RNAs (lncRNAs) have been shown to function as components of molecular machines that play fundamental roles in biology. While the number of annotated lncRNAs in mammalian genomes has greatly expanded, studyin
Externí odkaz:
https://doaj.org/article/c0afc736c1d14340901a97d94751f3ae
Autor:
Nabil Seidah, Vatsal Sachan, Mailys Le Dévéhat, Anna Roubtsova, Rachid Essalmani, Damien Garçon, Delia Susan-Resiga, Stéphanie Duval, Sahar Mikaeeli, Josée Hamelin, Alexandra Evagelidis, Michael Chong, Guillaume Pare, Elizabeta Chernetsova, Zu-hua Gao, Isabelle Robillard, Matthieu Ruiz, Vincent Quoc-Huy Trinh, Jennifer Estall, May Faraj, Jean-Francois Laurendeau, Richard Austin, Martin Sauvageau, Annik Prat, Robert Scott Kiss
Epidemiological evidence links the proprotein convertase subtilisin/kexin 7 (PCSK7) to triglyceride (TG) metabolism. PCSK7-SNPs gain-of-function and loss-of-function variants were associated with higher and lower levels of plasma apoB and TGs, respec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7611159c671b9f23fc40d49502551155
https://doi.org/10.21203/rs.3.rs-2724841/v1
https://doi.org/10.21203/rs.3.rs-2724841/v1
Autor:
Abigail F. Groff, Diana B. Sanchez-Gomez, Marcela M.L. Soruco, Chiara Gerhardinger, A. Rasim Barutcu, Eric Li, Lara Elcavage, Olivia Plana, Lluvia V. Sanchez, James C. Lee, Martin Sauvageau, John L. Rinn
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2178-2186 (2016)
The Linc-p21 locus, encoding a long non-coding RNA, plays an important role in p53 signaling, cell-cycle regulation, and tumor suppression. However, despite extensive study, confusion exists regarding its mechanism of action: is activity driven by th
Externí odkaz:
https://doaj.org/article/b97cea6fc71b4eaeb775493f94628854
Autor:
Martin Sauvageau, Loyal A Goff, Simona Lodato, Boyan Bonev, Abigail F Groff, Chiara Gerhardinger, Diana B Sanchez-Gomez, Ezgi Hacisuleyman, Eric Li, Matthew Spence, Stephen C Liapis, William Mallard, Michael Morse, Mavis R Swerdel, Michael F D’Ecclessis, Jennifer C Moore, Venus Lai, Guochun Gong, George D Yancopoulos, David Frendewey, Manolis Kellis, Ronald P Hart, David M Valenzuela, Paola Arlotta, John L Rinn
Publikováno v:
eLife, Vol 2 (2013)
Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few have been tested for in vivo relevance through genetic ablation in animal models. To investigate the functional relevance of lncRNAs in various physiological cond
Externí odkaz:
https://doaj.org/article/5fdb35f4c02f45c69bc508db25a26cb3
Autor:
Martin, Sauvageau
Publikováno v:
Advances in experimental medicine and biology. 1203
RNA-protein interactions are essential to a variety of biological processes. The realization that mammalian genomes are pervasively transcribed brought a tidal wave of tens of thousands of newly identified long noncoding RNAs (lncRNAs) and raised que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27485499d9f4d3ea6b7c689f205093b8
https://pubmed.ncbi.nlm.nih.gov/31811638
https://pubmed.ncbi.nlm.nih.gov/31811638
Autor:
Martin Sauvageau, Guy Sauvageau
Publikováno v:
PLoS Biology, Vol 6, Iss 4, p e113 (2008)
Externí odkaz:
https://doaj.org/article/1ba346ac3e484bd6a44ad4793ed3cc97
Autor:
James Lee, Olivia Plana, Lluvia V. Sanchez, Abigail F. Groff, John L. Rinn, Lara Elcavage, Eric Li, Chiara Gerhardinger, Diana B. Sanchez-Gomez, A. Rasim Barutcu, Marcela M.L. Soruco, Martin Sauvageau
Publikováno v:
Cell Reports, Vol 16, Iss 8, Pp 2178-2186 (2016)
SummaryThe Linc-p21 locus, encoding a long non-coding RNA, plays an important role in p53 signaling, cell-cycle regulation, and tumor suppression. However, despite extensive study, confusion exists regarding its mechanism of action: is activity drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3350db22c26b29c405c7dc5a627994a
Autor:
S. van Heesch, J. Felicitas Schulz, Gabrijela Dumbovic, C. Kirby, Nydia Chang, Chiara Gerhardinger, Christian Much, Emily Jacobs-Palmer, Abigail F. Groff, Kyle M. Turner, Nimrod D. Rubinstein, Jordan P. Lewandowski, Martin Sauvageau, Taeyoung Hwang, Stephen C. Liapis, Hopi E. Hoekstra, A. R. Watson, C.-L. Müller, John L. Rinn, Norbert Hubner
BackgroundSeveral long noncoding RNAs (lncRNAs) have been shown to function as central components of molecular machines that play fundamental roles in biology. While the number of annotated lncRNAs in mammalian genomes has greatly expanded, their fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::400c00c8b4c950d5911df40a32e920f3
https://doi.org/10.1101/562066
https://doi.org/10.1101/562066
Autor:
Martin Sauvageau
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030314330
RNA-protein interactions are essential to a variety of biological processes. The realization that mammalian genomes are pervasively transcribed brought a tidal wave of tens of thousands of newly identified long noncoding RNAs (lncRNAs) and raised que
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d2c2b07b6a57329ff65855b43c1949d
https://doi.org/10.1007/978-3-030-31434-7_10
https://doi.org/10.1007/978-3-030-31434-7_10