Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Martin S Pavelka"'
Autor:
Nicholas James Miller, Dionysia Dimitrakopoulou, Laurel A. Baglia, Martin S. Pavelka, Jacques Robert
Publikováno v:
Microorganisms, Vol 12, Iss 6, p 1120 (2024)
Mycobacterium abscessus (Mab) is an emerging human pathogen that has a high rate of incidence in immunocompromised individuals. We have found a putative secondary metabolite pathway within Mab, which may be a key factor in its pathogenesis. This nove
Externí odkaz:
https://doaj.org/article/edb662adb1ef4d8eaf38adb53f69b912
Publikováno v:
Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2023.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f797e780c374aee2d507fa2b36c8eabb
https://doi.org/10.1117/12.2648350
https://doi.org/10.1117/12.2648350
Autor:
Zanah K. Francis, Akeisha N. Sanders, Dean C. Crick, Sebabrata Mahapatra, M. Nurul Islam, Martin S. Pavelka
Publikováno v:
J Bacteriol
The peptidoglycan of mycobacteria has two types of direct cross-links, classical 4-3 cross-links that occur between diaminopimelate (DAP) and alanine residues, and nonclassical 3-3 cross-links that occur between DAP residues on adjacent peptides. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e32d386eedebd723ab5885922c3360
https://europepmc.org/articles/PMC9879121/
https://europepmc.org/articles/PMC9879121/
Autor:
David C Nguyen, Sarah N Redmond, Khalid M Dousa, Christopher Bethel, Magdalena A Taracila, Qing Li, Sebastian G Kurz, Martin S Pavelka, Krisztina Papp-Wallace, Steven M Holland, Barry N Kreiswirth, Henry Boom, Robert A Bonomo
Publikováno v:
Open Forum Infectious Diseases. 9
Background Drug-resistant tuberculosis (DR TB) is a deadly, difficult-to-treat infection, and new treatment strategies are needed. Despite the wide success of β-lactams (BLs), DR TB guidelines only include meropenem (MEM) and imipenem (IPM), given w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::641e23889e7ebe1e808ca2615af04c02
https://doi.org/10.1093/ofid/ofac492.1261
https://doi.org/10.1093/ofid/ofac492.1261
Publikováno v:
Developmental & Comparative Immunology. 139:104594
Mycobacterial infections represent major concerns for aquatic and terrestrial vertebrates including humans. Although our current knowledge is mostly restricted to Mycobacterium tuberculosis and mammalian host interactions, increasing evidence suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241a10c6212040f0f7b83a8a63e73a7a
https://doi.org/10.1016/j.dci.2022.104594
https://doi.org/10.1016/j.dci.2022.104594
Autor:
Kun Hyoe Rhoo, María J. Forzán, Jacques Robert, Martin S. Pavelka, Adil Mahboob Khan, Eva-Stina Edholm, Anthony W Waddle
Publikováno v:
The Journal of Immunology. 203:2679-2688
Mycobacterium marinum is a promiscuous pathogen infecting many vertebrates, including humans, whose persistent infections are problematic for aquaculture and public health. Among unsettled aspects of host–pathogen interactions, the respective roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edcc70a01f83c932b36e3b6fa8962a5
https://doi.org/10.4049/jimmunol.1900459
https://doi.org/10.4049/jimmunol.1900459
Autor:
Michael Cynamon, Dionysia Dimitrakopoulou, Jacques Robert, Matthieu Paiola, Carolyn M. Shoen, Arianna Lopez, Martin S. Pavelka
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 806, p 806 (2021)
Volume 22
Issue 2
International Journal of Molecular Sciences, Vol 22, Iss 806, p 806 (2021)
Mycobacterium abscessus (Mab) is an emerging, nontuberculosis mycobacterium (NTM) that infects humans. Mab has two morphotypes, smooth (S) and rough (R), related to the production of glycopeptidolipid (GPL), that differ in pathogenesis. To further un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dc1c98ec314ac9abe1944e4b087faa
Publikováno v:
Microbiology. 163:1399-1408
Mycobacterium abscessus is a fast-growing environmental organism and an important emerging pathogen. It is highly resistant to many antibiotics and undergoes a smooth to rough colony morphology change that appears to be important for pathogenesis. Sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115999b700bdc7d8453d579362784bc5
https://doi.org/10.1099/mic.0.000528
https://doi.org/10.1099/mic.0.000528
Autor:
Marcos M. Pires, Martin S. Pavelka, Sung Joon Kim, Dean C. Crick, Moagi Shaku, M. Nurul Islam, Sean E. Pidgeon, Binayak Rimal, Julia M. Nelson, Bavesh D. Kana, Alexis J. Apostolos
Publikováno v:
ACS Chemical Biology
Peptidoglycan (PG) is a cross-linked, meshlike scaffold endowed with the strength to withstand the internal pressure of bacteria. Bacteria are known to heavily remodel their peptidoglycan stem peptides, yet little is known about the physiological imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb2d4daf8634febd7a437b6fd38dbfa
https://doi.org/10.1021/acschembio.9b00427
https://doi.org/10.1021/acschembio.9b00427
Autor:
William J. Zuercher, Rebecca Procknow, Rob Striker, David H. Drewry, Jeffrey Beczkiewicz, Nathan Teachout, Kenneth A. Satyshur, Martin S. Pavelka, Adam J. Schaenzer, Nathan Wlodarchak, John-Demian Sauer
Publikováno v:
Molecular pharmaceutics. 15(11)
New tools and concepts are needed to combat antimicrobial resistance. Actinomycetes and firmicutes share several eukaryotic-like Ser/Thr kinases (eSTK) that offer antibiotic development opportunities, including PknB, an essential mycobacterial eSTK.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565f849d0f340550b6a61299fa848ab8
https://pubmed.ncbi.nlm.nih.gov/30285456
https://pubmed.ncbi.nlm.nih.gov/30285456