Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Martin S Naradikian"'
Autor:
Breanna DiAndreth, Kiran Deshmukh, Jee-Young Mock, Talar Tokatlian, Alexander Kamb, Shruti Sharma, Grace E Asuelime, Dora Toledo Warshaviak, Mark E Daris, Kristian Bolanos, Breanna L Luna, Martin S Naradikian, Agnes E Hamburger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/b49783de028b41c1864f6aaaa8be401c
Autor:
Jee-Young Mock, Aaron Winters, Timothy P. Riley, Richele Bruno, Martin S. Naradikian, Shruti Sharma, Claudia A. Jette, Ryan Elshimali, Casey Gahrs, Dora Toledo-Warshaviak, Anthony P. West, Jr., Alexander Kamb, Agnes E. Hamburger
Publikováno v:
Molecular Therapy: Oncolytics, Vol 27, Iss , Pp 157-166 (2022)
Innovative cell-based therapies are important new weapons in the fight against difficult-to-treat cancers. One promising strategy involves cell therapies equipped with multiple receptors to integrate signals from more than one antigen. We developed a
Externí odkaz:
https://doaj.org/article/02be393959cd48e798b19c08859c447f
Autor:
Spencer E. Brightman, Martin S. Naradikian, Rukman R. Thota, Angelica Becker, Leslie Montero, Milad Bahmanof, Ashmitaa Logandha Ramamoorthy Premlal, Jason A. Greenbaum, Bjoern Peters, Ezra E.W. Cohen, Aaron M. Miller, Stephen P. Schoenberger
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
CD4+ T cells play a critical role in antitumor immunity via recognition of peptide antigens presented on MHC class II (MHC-II). Although some solid cancers can be induced to express MHC-II, the extent to which this enables direct recognition by tumor
Externí odkaz:
https://doaj.org/article/269a1b54d04f495aa248feef28743e01
Autor:
Agnes E. Hamburger, Alexander Kamb, Dora Toledo Warshaviak, Aaron D. Martin, Mark E. Daris, Jee-Young Mock, Martin S. Naradikian, Grace E. Asuelime, Talar Tokatlian
S.Figures 1-5 and S.Table 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c296a88e2a599fde10d0c2e53bccd3ff
https://doi.org/10.1158/2767-9764.22544123
https://doi.org/10.1158/2767-9764.22544123
Autor:
Talar Tokatlian, Grace E. Asuelime, Martin S. Naradikian, Jee-Young Mock, Mark E. Daris, Aaron D. Martin, Dora Toledo Warshaviak, Alexander Kamb, Agnes E. Hamburger
Publikováno v:
Cancer Research Communications. 2:58-65
Neoantigens are among the most intriguing potential immuno-oncology targets because, unlike many cancer targets that are expressed on normal tissues, they are by definition restricted to cancer cells. Medicines directed at common neoantigens such as
Autor:
Talar Tokatlian, Grace E Asuelime, Jee-Young Mock, Breanna DiAndreth, Shruti Sharma, Dora Toledo Warshaviak, Mark E Daris, Kristian Bolanos, Breanna L Luna, Martin S Naradikian, Kiran Deshmukh, Agnes E Hamburger, Alexander Kamb
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
BackgroundMesothelin (MSLN) is a classic tumor-associated antigen that is expressed in lung cancer and many other solid tumors. However, MSLN is also expressed in normal mesothelium which creates a significant risk of serious inflammation for MSLN-di
Autor:
Spencer E Brightman, Angelica Becker, Rukman Thota, Martin S Naradikian, Ryan Griswold, Joseph S Dolina, Stephen P Schoenberger
Publikováno v:
The Journal of Immunology. 208:180.06-180.06
The expansion of neoantigen (NeoAg)-specific T cells often accompanies clinical responses to immunotherapies such as immune checkpoint blockade (ICB), adoptive cellular therapy (ACT), and personalized cancer vaccines (PCV), highlighting their importa
Autor:
Michael P. Cancro, Richard M. Scearce, Peter T. Hraber, Hua-Xin Liao, Elinor Willis, Shiu Lok Hu, Daniel A. Balikov, Katalin Karikó, Houping Ni, Celia C. LaBranche, Arpita Myles, Charles Q. Li, Norbert Pardi, Kelly K. Lee, Jenna L. Lobby, Florian Krammer, Ying K. Tam, Patricia Polacino, Kevin O. Saunders, David C. Montefiori, Bette T. Korber, Laura L. Sutherland, Letitia D. Jones, Michael J. Hogan, Michael J. Hope, Mark G. Lewis, Derek W. Cain, Laurence C. Eisenlohr, István Tombácz, Barbara L. Mui, Scott E. Hensley, M. Anthony Moody, Kaela Parkhouse, Hans P. Verkerke, Martin S. Naradikian, Drew Weissman, Hiromi Muramatsu, Thomas D. Madden, Barton F. Haynes
Publikováno v:
The Journal of Experimental Medicine
Pardi and colleagues report on a vaccine platform in which purified, antigen-encoding, nucleoside-modified mRNA is encapsulated in lipid nanoparticles. Immunization with this vaccine elicits potent T follicular helper cell, germinal center B cell, an
Autor:
Maria Imun, Mark L. Sandberg, Yuta Ando, Wen-Hua Lee, Xueyin Wang, Fernando Fisher, Michele McElvain, Kiran Deshmukh, Agnes E. Hamburger, Han Xu, Lu-Min Wong, Chuck Li, Breanna DiAndreth, Alexander Kamb, David M.C. Ju, Grant B Gabrelow, Dora Toledo-Warshaviak, Sanam Shafaattalab, Daniel P Nampe, Talar Tokatlian, Mark E. Daris, Shruti Sharma, Edwin Liu, Jee-Young Mock, Martin S. Naradikian, Kristian Bolanos-Ibarra, Aaron D. Martin, Grace E. Asuelime
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A131-A131
BackgroundMesothelin (MSLN) and carcinoembryonic antigen (CEA) are classic tumor-associated antigens that are expressed in many solid tumors including the majority of lung, colorectal and pancreatic cancers. However, both MSLN and CEA are also expres
Autor:
Taku Kambayashi, Amanda M. Schmidt, Krishna Moody, Ann Marshak-Rothstein, Nathaniel M. Green, Michael A. Oropallo, William Stohl, Vishal J. Sindhava, Stephanie Dorta-Estremera, Lauren E. Higdon, Martin S. Naradikian, Kerstin Nündel, Arpita Myles, Lin Zhou, Michael P. Cancro, Wei Cao
Publikováno v:
Journal of Clinical Investigation. 127:1651-1663
Mature B cell pools retain a substantial proportion of polyreactive and self-reactive clonotypes, suggesting that activation checkpoints exist to reduce the initiation of autoreactive B cell responses. Here, we have described a relationship among the