Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Martin S, Weber"'
Autor:
Tobias Derfuss, Robert Bermel, Chien-Ju Lin, Stephen L. Hauser, Ludwig Kappos, Timothy Vollmer, Giancarlo Comi, Gavin Giovannoni, Hans-Peter Hartung, Martin S. Weber, Jianmei Wang, Nikki Jessop, Cathy Chognot, Licinio Craveiro, Amit Bar-Or
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Patients with multiple sclerosis (PwMS) have an increased risk of infections. Objectives: To characterize incidence, clinical characteristics, outcomes and risk factors of infections, and serious infections (SIs) in ocrelizumab (OCR)-trea
Externí odkaz:
https://doaj.org/article/aed1889aa6044652a518886ae29cb31b
Autor:
Lidia Stork, Michael Haupts, Niels Kruse, Petra Spill-Askeridis, Adriane Kutllovci, Martin S. Weber, Wolfgang Brück, Imke Metz
Publikováno v:
Free Neuropathology, Vol 4 (2023)
Background and objectives: In progressive multiple sclerosis (MS) patients, CNS inflammation trapped behind a closed blood brain barrier drives continuous neuroaxonal degeneration, thus leading to deterioration of neurological function. Therapeutics
Externí odkaz:
https://doaj.org/article/9f314bb80a614a2a8da97922e97caaf2
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 497 (2024)
Factor XIII is a transglutaminase enzyme that plays a crucial role in hemostasis and wound healing. It crosslinks fibrin strands, stabilizing clots and promoting clot resistance to fibrinolysis. Additionally, Factor XIII has been found to have multip
Externí odkaz:
https://doaj.org/article/315dfd91ff604adcb2a997c0340e52e5
Autor:
Martin S. Weber, Mathias Buttmann, Sven G. Meuth, Petra Dirks, Erwan Muros-Le Rouzic, Julius C. Eggebrecht, Stefanie Hieke-Schulz, Jost Leemhuis, Tjalf Ziemssen
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundReal-world relapsing multiple sclerosis (RMS) and primary progressive MS (PPMS) populations may be more diverse than in clinical trials. Here, we present a first analysis of safety, adherence and persistence data from a real-world cohort of
Externí odkaz:
https://doaj.org/article/5c361ada58c94ccf8af5b50ba90fce7e
Autor:
Leonie Meyer-Heemsoth, Katja Mitschke, Jasmina Bier, Konstantin Schütz, Andreas Villunger, Tobias J. Legler, Martin S. Weber, Fred Lühder, Holger M. Reichardt
Publikováno v:
Cells, Vol 12, Iss 3, p 450 (2023)
Glucocorticoids (GCs) are used to treat inflammatory disorders such as multiple sclerosis (MS) by exerting prominent activities in T cells including apoptosis induction and suppression of cytokine production. However, little is known about their impa
Externí odkaz:
https://doaj.org/article/7aa68e66f5924d57a5e3dda753c2a6fd
Autor:
Jan Traub, Katja Grondey, Tobias Gassenmaier, Dominik Schmitt, Georg Fette, Stefan Frantz, Valérie Boivin-Jahns, Roland Jahns, Stefan Störk, Guido Stoll, Theresa Reiter, Ulrich Hofmann, Martin S. Weber, Anna Frey
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10304 (2022)
Acute ischemic cardiac injury predisposes one to cognitive impairment, dementia, and depression. Pathophysiologically, recent positron emission tomography data suggest astroglial activation after experimental myocardial infarction (MI). We analyzed p
Externí odkaz:
https://doaj.org/article/e6d5c4cea0f7498b8b3ca6cc9144a32e
Autor:
Heinz Wiendl, Ralf Gold, Thomas Berger, Tobias Derfuss, Ralf Linker, Mathias Mäurer, Orhan Aktas, Karl Baum, Martin Berghoff, Stefan Bittner, Andrew Chan, Adam Czaplinski, Florian Deisenhammer, Franziska Di Pauli, Renaud Du Pasquier, Christian Enzinger, Elisabeth Fertl, Achim Gass, Klaus Gehring, Claudio Gobbi, Norbert Goebels, Michael Guger, Aiden Haghikia, Hans-Peter Hartung, Fedor Heidenreich, Olaf Hoffmann, Boris Kallmann, Christoph Kleinschnitz, Luisa Klotz, Verena I. Leussink, Fritz Leutmezer, Volker Limmroth, Jan D. Lünemann, Andreas Lutterotti, Sven G. Meuth, Uta Meyding-Lamadé, Michael Platten, Peter Rieckmann, Stephan Schmidt, Hayrettin Tumani, Frank Weber, Martin S. Weber, Uwe K. Zettl, Tjalf Ziemssen, Frauke Zipp
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 14 (2021)
Multiple sclerosis is a complex, autoimmune-mediated disease of the central nervous system characterized by inflammatory demyelination and axonal/neuronal damage. The approval of various disease-modifying therapies and our increased understanding of
Externí odkaz:
https://doaj.org/article/cee55fa870514dd8bb41f4326e4ce63e
Autor:
Laura Fernandez Garcia-Agudo, Agnes A. Steixner-Kumar, Yasmina Curto, Nadine Barnkothe, Imam Hassouna, Sebastian Jähne, Umer Javed Butt, Katharina Grewe, Martin S. Weber, Kim Green, Silvio Rizzoli, Juan Nacher, Klaus-Armin Nave, Hannelore Ehrenreich
Publikováno v:
Cell Reports, Vol 36, Iss 8, Pp 109548- (2021)
Summary: In adult cornu ammonis hippocampi, erythropoietin (EPO) expression drives the differentiation of new neurons, independent of DNA synthesis, and increases dendritic spine density. This substantial brain hardware upgrade is part of a regulator
Externí odkaz:
https://doaj.org/article/42f27ee525b44a1987ebb71c0214859d
Autor:
Jan W. Traub, Hannah L. Pellkofer, Katja Grondey, Ira Seeger, Christoph Rowold, Wolfgang Brück, Leila Husseini, Silke Häusser-Kinzel, Martin S. Weber
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background In the past, multiple sclerosis (MS) medications have been primarily designed to modulate T cell properties. Based on the emerging concept that B cells are equally important for the propagation of MS, we compared the effect of fou
Externí odkaz:
https://doaj.org/article/a80c2f5eb60f4d8086a2e5ece6cce544
Autor:
Anastasia Geladaris, Silke Häusser-Kinzel, Roxanne Pretzsch, Nitzan Nissimov, Klaus Lehmann-Horn, Darius Häusler, Martin S. Weber
Publikováno v:
Acta Neuropathologica. 145:461-477
B cells contribute to chronic inflammatory conditions as source of antibody-secreting plasma cells and as antigen-presenting cells activating T cells, making anti-CD20-mediated B cell depletion a widely used therapeutic option. B cells or B cell subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4145738d3961ceea72f3ddaae18f02ae
https://doi.org/10.1007/s00401-023-02552-6
https://doi.org/10.1007/s00401-023-02552-6