Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Martin Röllinghoff"'
Publikováno v:
Scandinavian Journal of Immunology. 6:1121-1125
Cytotoxic T lymphocytes specific for immune alloantigens controlled by alleles of the Ly system have been induced in vivo. These results were obtained either in a secondary type of response or by treating mice before immunization with a single dose o
Publikováno v:
The Journal of Immunology. 180:3436-3446
In searching for immunogenic molecules with the potential to induce protective immune responses against tuberculosis, we developed an ex vivo model to study frequency, phenotype, and effector functions of human T lymphocytes recognizing hydrophobic A
Autor:
Dorothée Hofmann, Martin Röllinghoff, Franz Rödel, Rolf Sauer, Judith Auer, H.U. Beuscher, Ludwig Keilholz
Publikováno v:
Strahlentherapie und Onkologie. 184:41-47
Low-dose radiotherapy (LD-RT) is known to exert an anti-inflammatory effect, however, the underlying molecular mechanisms are not fully understood. The manipulation of polymorphonuclear neutrophil (PMN) function and/or recruitment may be one mechanis
Autor:
Roger Bouillon, Giovanni Pacini, Martin Röllinghoff, Josef Syka, Stig Slordahl, Isabel Varela-Nieto, Kirsten Steinhausen, Maria Manuela Nogueira
Publikováno v:
Lancet (London, England). 386(10001)
The previous framework programmes of the EU spent less than 15% of their budget on medical research. In the current programme, Horizon 2020, only 10·5% of the initial budget of €80 billion is dedicated to biomedical and health-related research. Th
Autor:
George J. Cianciolo, Maike Buettner, Rauf Bhat, Manfred Wagner, Joachim H. Ficker, Elmar Stössel, Steffen Stenger, Christoph Meinken, Max Bastian, Martin Röllinghoff, Gerhard Faller
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
Dendritic cells (DCs) are a key part of host defense against microbial pathogens, being part of the innate immune system, but also instructing the adaptive T cell response. This study was designed to evaluate whether human DCs directly contribute to
Autor:
Miriam Sehnal, Peter Staib, Ayfer Binder, Klaus Schröppel, Brad N. Taylor, Joachim Morschhäuser, Martin Röllinghoff, Antje Biesemeier
Publikováno v:
Infection and Immunity. 73:1828-1835
Vaginal infections caused by the opportunistic yeast Candida albicans are a significant problem in women of child-bearing age. Several factors are recognized as playing a crucial role in the pathogenesis of superficial candidiasis; these factors incl
Autor:
Martin Röllinghoff, Markus Schnare, Udo Meissner, Daniela Klaffenbach, Wolfgang Rascher, Jörg Dötsch
Publikováno v:
American Journal of Reproductive Immunology. 53:77-84
Problem: Toll-like receptors (TLRs) are expressed on placental cells. The aim of this study is to analyze signaling components activated in placenta cells after TLR ligand engagement. Methods of study: In chorioncarcimoma cell lines the regulation of
Publikováno v:
Immunobiology. 209:225-233
Non-peptide antagonists of chemokine receptors are considered an intriguing alternative for the treatment of acute and chronic diseases. Particularly the recruitment of neutrophils to inflammatory sites often causes harmful side effects and is mediat
Autor:
Paula S. Hochman, Alexandra Wandersee-Steinhäuser, Jochen Mattner, Martin Röllinghoff, Gerard R. Majeau, Andreas Pahl, Christian Bogdan
Publikováno v:
The Journal of Immunology. 172:7574-7582
Type I IFNs (IFN-αβ) exert potent antiviral and immunoregulatory activities during viral infections, but their role in bacterial or protozoan infections is poorly understood. In this study, we demonstrate that the application of low, but not of hig
Publikováno v:
Infection and Immunity. 71:7215-7218
Myeloid differentiation protein 88 (MyD88) is a general adaptor for the signaling cascade through receptors of the Toll/IL-1R family. When infected withLeishmania majorparasites, MyD88-deficient mice displayed a dramatically enhanced parasite burden