Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Martin Reichel"'
Autor:
Frederic Brösecke, Anja Pfau, Theresa Ermer, Ana Beatriz Dein Terra Mota Ribeiro, Lisa Rubenbauer, Veena S. Rao, Sarah Burlein, Bernd Genser, Martin Reichel, Peter S. Aronson, Steven Coca, Felix Knauf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Oxalate, a uremic toxin that accumulates in dialysis patients, is associated with cardiovascular disease. As oxalate crystals can activate immune cells, we tested the hypothesis that plasma oxalate would be associated with cytokine concentra
Externí odkaz:
https://doaj.org/article/24fb1114357e486c97980c01126c01b9
Autor:
Byung Jo Choi, Min Hee Park, Kang Ho Park, Wan Hui Han, Hee Ji Yoon, Hye Yoon Jung, Ju Yeon Hong, Md Riad Chowdhury, Kyung Yeol Kim, Jihoon Lee, Im-Sook Song, Minyeong Pang, Min-Koo Choi, Erich Gulbins, Martin Reichel, Johannes Kornhuber, Chang-Won Hong, Changho Kim, Seung Hyun Kim, Edward H. Schuchman, Hee Kyung Jin, Jae-sung Bae
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Acid sphingomyelinase (ASM) is a sphingolipid metabolizing enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide, and previous work has shown it is upregulated in models of Alzheimer’s disease. Here the authors demonstrate in a mouse mo
Externí odkaz:
https://doaj.org/article/52c99cf51ae64f39b52ec19ee7f53cf4
Autor:
Guido Schröder, Martin Reichel, Sven Spiegel, Marko Schulze, Andreas Götz, Semjon Bugaichuk, Julian Ramin Andresen, Claus Maximilian Kullen, Reimer Andresen, Hans-Christof Schober
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-17 (2022)
Abstract Background The purpose of the study was to investigate associations between biomechanical resilience (failure load, failure strength) and the microarchitecture of cancellous bone in the vertebrae of human cadavers with low bone density with
Externí odkaz:
https://doaj.org/article/d97dfae6715b4cf8b79e909e114625bd
Publikováno v:
JAAD Case Reports, Vol 14, Iss , Pp 13-16 (2021)
Externí odkaz:
https://doaj.org/article/78f44ff8ba1e4bcc91bc3f217f45f4a5
Publikováno v:
Case Reports in Pathology, Vol 2021 (2021)
This report documents an exophytic, pedunculated nodule in a 74-year-old man that upon histopathological examination revealed an atypical spindle cell/pleomorphic lipomatous tumor (ASPLT) confined to the papillary and reticular dermis, representing t
Externí odkaz:
https://doaj.org/article/2856630f05b441dd92f0e0e1c8d4b5fc
Autor:
Theresa Ermer, Christoph Kopp, John R. Asplin, Ignacio Granja, Mark A. Perazella, Martin Reichel, Thomas D. Nolin, Kai-Uwe Eckardt, Peter S. Aronson, Fredric O. Finkelstein, Felix Knauf
Publikováno v:
Kidney International Reports, Vol 2, Iss 6, Pp 1050-1058 (2017)
Calcium oxalate supersaturation is regularly exceeded in the plasma of patients with end-stage renal disease (ESRD). Previous reports have indicated that hemodialfiltration (HDF) lowers elevated plasma oxalate (POx) concentrations more effectively co
Externí odkaz:
https://doaj.org/article/f1585e28e43a4dedaaedc6d7b140f2a2
Autor:
Anja Pfau, Monika Wytopil, Kinsuk Chauhan, Martin Reichel, Steve Coca, Peter S. Aronson, Kai-Uwe Eckardt, Felix Knauf
Publikováno v:
Kidney International Reports, Vol 6, Iss 4, Pp 1194-1195 (2021)
Externí odkaz:
https://doaj.org/article/27ad0225b78b4d33bd9c1c6046b6e416
Autor:
Cosima Rhein, Iulia Zoicas, Lena M. Marx, Stefanie Zeitler, Tobias Hepp, Claudia von Zimmermann, Christiane Mühle, Tanja Richter-Schmidinger, Bernd Lenz, Yesim Erim, Martin Reichel, Erich Gulbins, Johannes Kornhuber
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5700 (2021)
Major depressive disorder (MDD) is a severe psychiatric condition with key symptoms of low mood and lack of motivation, joy, and pleasure. Recently, the acid sphingomyelinase (ASM)/ceramide system has been implicated in the pathogenesis of MDD. ASM i
Externí odkaz:
https://doaj.org/article/410c77b0b64b4afc83f69d33cedfb4a1
Autor:
Liubov S. Kalinichenko, Christiane Mühle, Volker Eulenburg, Marc Praetner, Martin Reichel, Erich Gulbins, Johannes Kornhuber, Christian P. Müller
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Major depression and alcohol use disorder are severe psychiatric diseases affecting the world's population with high comorbidity level. However, the pathogenesis of this comorbidity remains unclear, and no selective treatment for this condition is av
Externí odkaz:
https://doaj.org/article/c3900a67cbb04b27a59997592dcb3ad6
Autor:
Iulia Zoicas, Fabian Schumacher, Burkhard Kleuser, Martin Reichel, Erich Gulbins, Anna Fejtova, Johannes Kornhuber, Cosima Rhein
Publikováno v:
Cells, Vol 9, Iss 5, p 1244 (2020)
Human and murine studies identified the lysosomal enzyme acid sphingomyelinase (ASM) as a target for antidepressant therapy and revealed its role in the pathophysiology of major depression. In this study, we generated a mouse model with overexpressio
Externí odkaz:
https://doaj.org/article/3e10dfc72350475c9cd25f481974f448