Zobrazeno 1 - 10
of 459
pro vyhledávání: '"Martin R. Weiser"'
Autor:
Canan Firat, Nil Urganci, Alexei Teplov, Emine Cesmecioglu, Nilay Bakoglu, Efsevia Vakiani, Peter Ntiamoah, Martin R. Weiser, Julio Garcia-Aguilar, Meera Hameed, Yukako Yagi, Jinru Shia
Publikováno v:
Diagnostics, Vol 14, Iss 16, p 1704 (2024)
In colorectal carcinoma (CRC), tumor deposits (TDs) are described as macroscopic/microscopic nests/nodules in the lymph drainage area discontinuous with the primary mass, without identifiable lymph node (LN) tissue, and not confined to vascular or pe
Externí odkaz:
https://doaj.org/article/2346b94241c6484fa0f3d2b614499f88
Autor:
David A. Lieb, Hannah M. Thompson, Floris S. Verheij, Jinru Shia, Francisco Sanchez-Vega, Georgios Karagkounis, Maria Widmar, Iris H. Wei, J. Joshua Smith, Garrett M. Nash, Martin R. Weiser, Philip B. Paty, Andrea Cercek, Leonard B. Saltz, Julio Garcia-Aguilar, Emmanouil Pappou
Publikováno v:
Cancers, Vol 16, Iss 15, p 2641 (2024)
(1) Background: Adenosquamous carcinoma (ASC) is a rare subtype of colon cancer. Its rarity makes characterization challenging, although colonic ASC is believed to present at more advanced stages and have worse outcomes versus adenocarcinoma. This st
Externí odkaz:
https://doaj.org/article/b92f68569f7a44caa262b9834cbfddd9
Autor:
Roni Rosen, Felipe F. Quezada-Diaz, Mithat Gönen, Georgios Karagkounis, Maria Widmar, Iris H. Wei, J. Joshua Smith, Garrett M. Nash, Martin R. Weiser, Philip B. Paty, Andrea Cercek, Paul B. Romesser, Francisco Sanchez-Vega, Mohammad Adileh, Diana Roth O’Brien, Carla Hajj, Vonetta M. Williams, Marina Shcherba, Ping Gu, Christopher Crane, Leonard B. Saltz, Julio Garcia Aguilar, Emmanouil Pappou
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 8, p 2156 (2024)
Background: Abdominoperineal resection (APR) has been advocated for persistent or recurrent disease after failure of chemoradiation (CRT) for anal squamous cell cancer (SCC). Treatment with salvage APR can potentially achieve a cure. This study aimed
Externí odkaz:
https://doaj.org/article/35b30b3b48b24adf9be9ea82ffee6fea
Autor:
Walid K. Chatila, Henry Walch, Jaclyn F. Hechtman, Sydney M. Moyer, Valeria Sgambati, David M. Faleck, Amitabh Srivastava, Laura Tang, Jamal Benhamida, Dorina Ismailgeci, Carl Campos, Fan Wu, Qing Chang, Efsevia Vakiani, Elisa de Stanchina, Martin R. Weiser, Maria Widmar, Rhonda K. Yantiss, Manish A. Shah, Adam J. Bass, Zsofia K. Stadler, Lior H. Katz, Ingo K. Mellinghoff, Nilay S. Sethi, Nikolaus Schultz, Karuna Ganesh, David Kelsen, Rona Yaeger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Colitis-associated cancers (CACs) develop in patients with inflammatory bowel disease and have distinct genomic features compared to sporadic colorectal cancers. Here, the authors characterize the genomic alterations of CAC tumors and dysplasia, find
Externí odkaz:
https://doaj.org/article/a4643e58f86e4dc1a8afd07151be6e8c
Autor:
Olusegun Isaac Alatise, Gregory C. Knapp, Avinash Sharma, Walid K. Chatila, Olukayode A. Arowolo, Olalekan Olasehinde, Olusola C. Famurewa, Adeleye D. Omisore, Akinwumi O. Komolafe, Olaejinrinde O. Olaofe, Aba I. Katung, David E. Ibikunle, Adedeji A. Egberongbe, Samuel A. Olatoke, Sulaiman O. Agodirin, Olusola A. Adesiyun, Ademola Adeyeye, Oladapo A. Kolawole, Akinwumi O. Olakanmi, Kanika Arora, Jeremy Constable, Ronak Shah, Azfar Basunia, Brooke Sylvester, Chao Wu, Martin R. Weiser, Ken Seier, Mithat Gonen, Zsofia K. Stadler, Yelena Kemel, Efsevia Vakiani, Michael F. Berger, Timothy A. Chan, David B. Solit, Jinru Shia, Francisco Sanchez-Vega, Nikolaus Schultz, Murray Brennan, J. Joshua Smith, T. Peter Kingham
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Understanding the molecular and phenotypic profile of colorectal cancer (CRC) in West Africa is important for early detection and treatment. Here, the authors use a multigene next-generation sequencing panel to identify genomic differences in Nigeria
Externí odkaz:
https://doaj.org/article/939275ce40494796b17543b64bb2bcce
Autor:
Jin K. Kim, Chin-Tung Chen, Ajaratu Keshinro, Asama Khan, Canan Firat, Chad Vanderbilt, Neil Segal, Zsofia Stadler, Jinru Shia, Vinod P. Balachandran, Martin R. Weiser
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Colon tumors with deficient DNA mismatch repair (dMMR) are generally infiltrated by T cells more densely than tumors with proficient mismatch repair (pMMR). However, high numbers of tumor-infiltrating lymphocytes (TILs) are found in select pMMR tumor
Externí odkaz:
https://doaj.org/article/31bf509150b74ece9d21dd5b56c61f62
Autor:
Emmanouil P. Pappou, Larissa K. Temple, Sujata Patil, J. Joshua Smith, Iris H. Wei, Garrett M. Nash, José G. Guillem, Maria Widmar, Martin R. Weiser, Philip B. Paty, Deborah Schrag, Julio Garcia-Aguilar
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Despite improvements in surgical techniques, functional outcomes and quality of life after therapy for rectal cancer remain suboptimal. We sought to prospectively evaluate the effect of bowel, bladder, and sexual functional outcomes on health-related
Externí odkaz:
https://doaj.org/article/ef006166e0254822b4c9f4bdba324667
Publikováno v:
Annals of Gastroenterological Surgery, Vol 5, Iss 1, Pp 32-38 (2021)
Abstract Locally advanced rectal cancer requires multidisciplinary care. In the United States, most patients are treated with neoadjuvant chemoradiation delivered over 25‐28 days, total mesorectal excision, and 4 months of adjuvant chemotherapy. Wh
Externí odkaz:
https://doaj.org/article/01d750ab25cb43f2a048f42d6c2e348c
Autor:
Gregory C. Knapp, Olusegun I. Alatise, Olalekan O. Olasehinde, Ademola Adeyeye, Omobolaji O. Ayandipo, Martin R. Weiser, T. Peter Kingham
Publikováno v:
Journal of Global Oncology, Vol 5, Pp 1-10 (2019)
PURPOSE: The global burden of colorectal cancer (CRC) will continue to increase for the foreseeable future, largely driven by increasing incidence and mortality in low- and middle-income countries (LMICs) such as Nigeria. METHODS: We used the Wilson-
Externí odkaz:
https://doaj.org/article/704af1c59cb0493091f35d167460feef
Quantitative assessment of tumor-infiltrating lymphocytes in mismatch repair proficient colon cancer
Autor:
Rosa M. Jimenez-Rodriguez, Sujata Patil, Ajaratu Keshinro, Jinru Shia, Efsevia Vakiani, Zsofia Stadler, Neil H. Segal, Rona Yaeger, Tsuyoshi Konishi, Yoshifumi Shimada, Maria Widmar, Iris Wei, Emmanouil Pappou, J. Joshua Smith, Garrett Nash, Philip Paty, Julio Garcia-Aguilar, Martin R. Weiser
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Tumor infiltrating lymphocytes (TIL), which represent host adaptive response to the tumor, were first identified at scanning magnification to select areas with the highest counts on hematoxylin and eosin slides, quantitated per high-power field (HPF)
Externí odkaz:
https://doaj.org/article/e3b7505e7cd74e1fa57c3200bbd9c45f