Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Martin R. Hodge"'
Autor:
Aaron M. Smith, Jonathan R. Walsh, John Long, Craig B. Davis, Peter Henstock, Martin R. Hodge, Mateusz Maciejewski, Xinmeng Jasmine Mu, Stephen Ra, Shanrong Zhao, Daniel Ziemek, Charles K. Fisher
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Background The ability to confidently predict health outcomes from gene expression would catalyze a revolution in molecular diagnostics. Yet, the goal of developing actionable, robust, and reproducible predictive signatures of phenotypes suc
Externí odkaz:
https://doaj.org/article/4a80ce019b8d4e889e86cf97f5025413
Autor:
Xinmeng Jasmine Mu, Shanrong Zhao, Craig Davis, Charles K. Fisher, Mateusz Maciejewski, Aaron M. Smith, Daniel Ziemek, Jonathan R. Walsh, Peter V. Henstock, John Long, Martin R. Hodge, Stephen Ra
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-18 (2020)
BMC Bioinformatics
BMC Bioinformatics
Background The ability to confidently predict health outcomes from gene expression would catalyze a revolution in molecular diagnostics. Yet, the goal of developing actionable, robust, and reproducible predictive signatures of phenotypes such as clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3175381829941bd35053b9f7be76c14
http://link.springer.com/article/10.1186/s12859-020-3427-8
http://link.springer.com/article/10.1186/s12859-020-3427-8
Autor:
Kevin D. Deane, Sean E. Connolly, Kazuhiko Yamamoto, Vivian P. Bykerk, Soumya Raychaudhuri, Zhanguo Li, Frank Nestle, Steven C. Hoffmann, Jennifer H. Anolik, Christopher D. Buckley, V. Michael Holers, Tom W J Huizinga, Jianping Guo, Lars Klareskog, Michael B. Brenner, Martin R. Hodge, Costantino Pitzalis
Publikováno v:
Annals of the Rheumatic Diseases, 79(5), 553-555. BMJ PUBLISHING GROUP
Patterns of innovation can be sustained (continuous) or rapid, sometimes even ‘disruptive’. A major difference is that in order to support disruptive innovation the support networks and its infrastructure often need to be changed dynamically to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1cf83ff8b9cc59c33820de3fefcf6a6
https://ora.ox.ac.uk/objects/uuid:c7901baa-188a-4678-94ed-e3d61634937a
https://ora.ox.ac.uk/objects/uuid:c7901baa-188a-4678-94ed-e3d61634937a
Autor:
Kosalaram Goteti, Elena Peeva, Christopher Banfield, Sanela Tarabar, Elizabeth Kieras, Martin R. Hodge, Michael L. Vazquez, Christine Alvey
Publikováno v:
British Journal of Clinical Pharmacology. 84:1776-1788
AIMS To determine the safety, tolerability, pharmacokinetics and pharmacodynamics of the Janus kinase 1-selective inhibitor, PF-04965842. METHODS This was a phase 1, first-in-human, randomized, double-blind, placebo-controlled, combination single- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9360f1c66c637a61dac262942c480f25
https://doi.org/10.1111/bcp.13612
https://doi.org/10.1111/bcp.13612
Autor:
Xinmeng Jasmine Mu, Shanrong Zhao, Aaron M. Smith, Craig Davis, Long J, Walsh, Stephen Ra, Peter V. Henstock, Mateusz Maciejewski, Martin R. Hodge, Charles K. Fisher, Daniel Ziemek
The ability to predict health outcomes from gene expression would catalyze a revolution in molecular diagnostics. This task is complicated because expression data are high dimensional whereas each experiment is usually small (e.g.,∼20,000 genes may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcadc680110b8f5609cd4874d8cfff9a
Autor:
Elizabeth Kieras, Christopher Banfield, Karen Page, Z.D. Draelos, David M. Pariser, Elena Peeva, Lori Ann Cox, Martin R. Hodge, D. Parsons-Rich, Mikhail Salganik, Sandeep Menon, G.J. Schmieder
Publikováno v:
The British journal of dermatology. 179(1)
Background PF-04965842 is an oral Janus Kinase 1 inhibitor being investigated for treatment of plaque psoriasis. Objectives To evaluate the efficacy, safety and tolerability of PF-04965842 in patients with moderate to severe plaque psoriasis. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99fbdb19f869cdb6a9ad5d330c09a66
https://pubmed.ncbi.nlm.nih.gov/28949012
https://pubmed.ncbi.nlm.nih.gov/28949012
Publikováno v:
Journal of Allergy and Clinical Immunology. 126:784-790
Background Cutaneous prostaglandin (PG) D 2 levels increase after scratching. Chemoattractant receptor–homologous molecule expressed on receptor on T H 2 cells (CRTH2) mediates chemotaxis to PGD 2 and is expressed on T H 2 cells and eosinophils, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9dea1fcd6978c6ac105a80da9e8aa75
https://doi.org/10.1016/j.jaci.2010.07.006
https://doi.org/10.1016/j.jaci.2010.07.006
Autor:
Nicola L. Harris, Ivo Sonderegger, Michael O. Kurrer, Benjamin J. Marsland, Manfred Kopf, Martin R. Hodge, Anja Fröhlich
Publikováno v:
Blood. 109:2023-2031
Interleukin 21 (IL-21) is a member of the common γ-chain family of cytokines, which influence a broad spectrum of immunologic responses. A number of studies have examined the function of IL-21, but its specific role in Th1/Th2-cell differentiation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c504d0d4ca5fa97bafb557382c3f1c
https://doi.org/10.1182/blood-2006-05-021600
https://doi.org/10.1182/blood-2006-05-021600
Autor:
Jose M. Lora, Jaclyn Sicoli, Michael J. Briskin, Kursteen S. Price, Joshua A. Boyce, Savita Bagga, Martin R. Hodge, Jose-Carlos Gutierrez-Ramos, Amal Al-Garawi, Michael D. Pickard
Publikováno v:
Journal of Allergy and Clinical Immunology. 112:1119-1126
Background Mast cells (MCs) proliferate in response to T H 2 cytokines and express genes de novo after activation. Limited information is available concerning the interplay between these events. Objective We explored the potential for T H 2 cytokines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3a5666d17b83238cd31047a4fd0317
https://doi.org/10.1016/j.jaci.2003.08.042
https://doi.org/10.1016/j.jaci.2003.08.042
Autor:
Ian Sabroe, Martin R. Hodge, Timothy J. Williams, Louise A. Jopling, Dolores M. Conroy, Clare M. Lloyd, David P. Andrew, James E. Pease
Publikováno v:
Journal of Leukocyte Biology. 74:558-563
The CC chemokine receptor 4 (CCR4) shows selectivity for the recruitment of memory T cell subsets, including those of the T helper cell type 2 (Th2) phenotype. In humans, CCR4+ T cells are recruited to the asthmatic lung in response to allergen chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85486c462220bd5ad2c49fa1a0cdfdd5
https://doi.org/10.1189/jlb.0103030
https://doi.org/10.1189/jlb.0103030