Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Martin R Goodier"'
Autor:
Martin R Goodier, Chiara Lusa, Sam Sherratt, Ana Rodriguez-Galan, Ron Behrens, Eleanor M Riley
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Cross-linking of FcγRIII (CD16) by immune complexes induces antibody dependent cellular cytotoxicity (ADCC) by natural killer (NK) cells, contributing to control of intracellular pathogens; this pathway can also be targeted for immunotherapy of canc
Externí odkaz:
https://doaj.org/article/a4617eb807014a1c884c4ee826ebf63d
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Studies to develop cell-based therapies for cancer and other diseases have consistently shown that purified human natural killer (NK) cells secrete cytokines and kill target cells after in vitro culture with high concentrations of cytokines. However,
Externí odkaz:
https://doaj.org/article/bc4888ac065344a7be689a7e33bf6f09
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Historically, human NK cells have been identified as CD3-CD56+CD16+/- lymphocytes. More recently it has been established that CD57 expression defines functionally discrete subpopulations of NK cells. On T cells, CD57 expression has been regarded as a
Externí odkaz:
https://doaj.org/article/8be3024d91c645059112b8a87f00d673
Autor:
Alansana Darboe, Carolyn M. Nielsen, Asia-Sophia Wolf, Jacob Wildfire, Ebrima Danso, Bakary Sonko, Christian Bottomley, Sophie E. Moore, Eleanor M. Riley, Martin R. Goodier
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Innate lymphoid cell (ILC) lineages mirror those of CD4+ T helper cell subsets, producing type 1, 2 and 3 cytokines respectively. Studies in adult human populations have shown contributions of non-cytotoxic ILC to immune regulation or pathogenesis in
Externí odkaz:
https://doaj.org/article/7e6f5e61f44348e88629c7734b2e785e
Autor:
Helen R. Wagstaffe, Omu Anzala, Hannah Kibuuka, Zacchaeus Anywaine, Sodiomon B. Sirima, Rodolphe Thiébaut, Laura Richert, Yves Levy, Christine Lacabaratz, Viki Bockstal, Kerstin Luhn, Macaya Douoguih, Martin R. Goodier
Publikováno v:
Vaccines, Vol 10, Iss 6, p 884 (2022)
Natural killer cells play an important role in the control of viral infections both by regulating acquired immune responses and as potent innate or antibody-mediated cytotoxic effector cells. NK cells have been implicated in control of Ebola virus in
Externí odkaz:
https://doaj.org/article/6610edce64264aaa83c15c61d4bb109b
Autor:
Georgi Shukarev, Helen R Wagstaffe, Jeroen N Stoop, Viki Bockstal, Eleanor M. Riley, Kerstin Luhn, Matthew D. Snape, Andrew J. Pollard, Martin R. Goodier, Macaya Douoguih, Elizabeth A. Clutterbuck
Publikováno v:
The Journal of Infectious Diseases
Wagstaffe, H R, Clutterbuck, E A, Bockstal, V, Stoop, J N, Luhn, K, Douoguih, M, Shukarev, G, Snape, M D, Pollard, A J, Riley, E M & Goodier, M R 2019, ' Antibody-Dependent Natural Killer Cell Activation after Ebola Vaccination ', The Journal of Infectious Diseases . https://doi.org/10.1093/infdis/jiz657
Wagstaffe, H R, Clutterbuck, E A, Bockstal, V, Stoop, J N, Luhn, K, Douoguih, M, Shukarev, G, Snape, M D, Pollard, A J, Riley, E M & Goodier, M R 2019, ' Antibody-Dependent Natural Killer Cell Activation after Ebola Vaccination ', The Journal of Infectious Diseases . https://doi.org/10.1093/infdis/jiz657
Background Antibody Fc-mediated functions, such as antibody-dependent cellular cytotoxicity, contribute to vaccine-induced protection against viral infections. Fc-mediated function of anti-Ebola glycoprotein (GP) antibodies suggest that Fc-dependent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc51bb99c3511833f7ff10db72b9468
https://doi.org/10.1093/infdis/jiz657
https://doi.org/10.1093/infdis/jiz657
Autor:
Helen R Wagstaffe, Martin R. Goodier, Natalie Prevatt, Eleanor M. Riley, Jason P. Mooney, Martin J. Holland, Ron H Behrens, Asia-Sophia Wolf, Harry Pickering, Joanna Houghton
Publikováno v:
The Journal of Immunology. 203:1609-1618
Cytokine-induced memory-like (CIML) NK cells generated in response to proinflammatory cytokines in vitro and in vivo can also be generated by vaccination, exhibiting heightened responses to cytokine stimulation months after their initial induction. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da7684103dc29b2d4f497b9433ff2f1
https://doi.org/10.4049/jimmunol.1801648
https://doi.org/10.4049/jimmunol.1801648
Autor:
Martin R. Goodier, Eleanor M. Riley
Publikováno v:
Clinical & Translational Immunology
Goodier, M R & Riley, E 2021, ' Regulation of the human NK cell compartment by pathogens and vaccines ', Clinical & translational immunology, vol. 10, e1244 . https://doi.org/10.1002/cti2.1244
Goodier, M R & Riley, E 2021, ' Regulation of the human NK cell compartment by pathogens and vaccines ', Clinical & translational immunology, vol. 10, e1244 . https://doi.org/10.1002/cti2.1244
Natural killer cells constitute a phenotypically diverse population of innate lymphoid cells with a broad functional spectrum. Classically defined as cytotoxic lymphocytes with the capacity to eliminate cells lacking self‐MHC or expressing markers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720c41217a48852adb64237f163b63e4
https://doi.org/10.1002/cti2.1244
https://doi.org/10.1002/cti2.1244