Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Martin Røssel-Larsen"'
Autor:
Olga Kubrak, Anne F. Jørgensen, Takashi Koyama, Mette Lassen, Stanislav Nagy, Jacob Hald, Gianluca Mazzoni, Dennis Madsen, Jacob B. Hansen, Martin Røssel Larsen, Michael J. Texada, Jakob L. Hansen, Kenneth V. Halberg, Kim Rewitz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Obesity impairs tissue insulin sensitivity and signaling, promoting type-2 diabetes. Although improving insulin signaling is key to reversing diabetes, the multi-organ mechanisms regulating this process are poorly defined. Here, we screen th
Externí odkaz:
https://doaj.org/article/c0b57de7e927476fa4302bfb4b15a306
Autor:
Ulrika Simone Spangsberg Petersen, Maja Dembic, Ainhoa Martínez-Pizarro, Eva Richard, Lise Lolle Holm, Jesper Foged Havelund, Thomas Koed Doktor, Martin Røssel Larsen, Nils J. Færgeman, Lourdes Ruiz Desviat, Brage Storstein Andresen
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102101- (2024)
Pseudoexons are nonfunctional intronic sequences that can be activated by deep-intronic sequence variation. Activation increases pseudoexon inclusion in mRNA and interferes with normal gene expression. The PCCA c.1285-1416A>G variation activates a ps
Externí odkaz:
https://doaj.org/article/ff8b723093454117929845437197aef9
Autor:
Henriette Haukedal, Giulia I. Corsi, Veerendra P. Gadekar, Nadezhda T. Doncheva, Shekhar Kedia, Noortje de Haan, Abinaya Chandrasekaran, Pia Jensen, Pernille Schiønning, Sarah Vallin, Frederik Ravnkilde Marlet, Anna Poon, Carlota Pires, Fawzi Khoder Agha, Hans H. Wandall, Susanna Cirera, Anja Hviid Simonsen, Troels Tolstrup Nielsen, Jørgen Erik Nielsen, Poul Hyttel, Ravi Muddashetty, Blanca I. Aldana, Jan Gorodkin, Deepak Nair, Morten Meyer, Martin Røssel Larsen, Kristine Freude
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Alzheimer’s disease (AD) is the most common cause of dementia, with no current cure. Consequently, alternative approaches focusing on early pathological events in specific neuronal populations, besides targeting the well-studied amyloid beta (Aβ)
Externí odkaz:
https://doaj.org/article/4d6bdc2e3ad742debbe8defab51f61f4
Autor:
Lucia Beltran-Camacho, Margarita Jimenez-Palomares, Marta Rojas-Torres, Ismael Sanchez-Gomar, Antonio Rosal-Vela, Sara Eslava-Alcon, Mª Carmen Perez-Segura, Ana Serrano, Borja Antequera-González, Jose Angel Alonso-Piñero, Almudena González-Rovira, Mª Jesús Extremera-García, Manuel Rodriguez-Piñero, Rafael Moreno-Luna, Martin Røssel Larsen, Mª Carmen Durán-Ruiz
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-20 (2020)
Abstract Background Critical limb ischemia (CLI) constitutes the most aggressive form of peripheral arterial occlusive disease, characterized by the blockade of arteries supplying blood to the lower extremities, significantly diminishing oxygen and n
Externí odkaz:
https://doaj.org/article/d6e5645e7e6c4e17996b246f8a80e461
Autor:
Valentina Siino, Pia Jensen, Peter James, Sonya Vasto, Antonella Amato, Flavia Mulè, Giulia Accardi, Martin Røssel Larsen
Publikováno v:
Nutrition and Metabolic Insights, Vol 14 (2021)
Obesity constitutes a major global health threat and is associated with a variety of diseases ranging from metabolic and cardiovascular disease, cancer to neurodegeneration. The hallmarks of neurodegeneration include oxidative stress, proteasome impa
Externí odkaz:
https://doaj.org/article/0e67a1893d5940d496e7cc6bc3bddb6e
Autor:
Helle Bogetofte, Pia Jensen, Justyna Okarmus, Sissel Ida Schmidt, Mikkel Agger, Matias Ryding, Peter Nørregaard, Christina Fenger, Xianmin Zeng, Jesper Graakjær, Brent James Ryan, Richard Wade-Martins, Martin Røssel Larsen, Morten Meyer
Publikováno v:
Neurobiology of Disease, Vol 132, Iss , Pp - (2019)
Mutations in parkin, encoded by the PARK2 gene, causes early-onset familial Parkinson's disease (PD), but dysfunctional parkin has also been implicated in sporadic PD. By combining human isogenic induced pluripotent stem cells (iPSCs) with and withou
Externí odkaz:
https://doaj.org/article/e98e9afd23534172af5a503933362700
Autor:
Livia Rosa-Fernandes, Fernanda Rodrigues Cugola, Fabiele Baldino Russo, Rebeca Kawahara, Caio Cesar de Melo Freire, Paulo Emílio Corrêa Leite, Ana Carolina Bassi Stern, Claudia Blanes Angeli, Danielle Bruna Leal de Oliveira, Stella Rezende Melo, Paolo Marinho de Andrade Zanotto, Edison Luiz Durigon, Martin Røssel Larsen, Patricia Cristina Baleeiro Beltrão-Braga, Giuseppe Palmisano
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Growing evidences have associated Zika virus (ZIKV) infection with congenital malformations, including microcephaly. Nonetheless, signaling mechanisms that promote the disease outcome are far from being understood, affecting the development of suitab
Externí odkaz:
https://doaj.org/article/6fe2a4f5c3ee4b55a87b4bd334a5611a
Autor:
Munazza Raza, Mirza, Rabia, Sultan, Muhammad Iqbal, Choudhary, Muhammad, Tahir, Martin Røssel, Larsen, Saria, Tariq, Saeed Ur, Rahman
Publikováno v:
Molecular omics. 18(2)
Areca nut or betel nut chewing is most frequently used in Pakistan and is associated with a high risk for oral cancer. Until now, however, there has not been any research conducted on the long-term effect(s) of betel nut chewing on the saliva proteom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9ce6393d61394ae4a286fa42e23b1939
https://pubmed.ncbi.nlm.nih.gov/34851339
https://pubmed.ncbi.nlm.nih.gov/34851339
Autor:
Jannie Marie Sand, Lise Larsen, Cory Hogaboam, Fernando Martinez, Meilan Han, Martin Røssel Larsen, Arkadiusz Nawrocki, Qinlong Zheng, Morten Asser Karsdal, Diana Julie Leeming
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84934 (2013)
OBJECTIVES: Fibrosis is characterized by excessive tissue remodeling resulting from altered expression of various growth factors, cytokines and proteases. We hypothesized that matrix metalloproteinase (MMP) mediated degradation of type IV collagen, a
Externí odkaz:
https://doaj.org/article/410f4b03bf6d4ca388ab2e4d55ed36ee
Autor:
Blanca Irene Aldana, Yu Zhang, Pia Jensen, Abinaya Chandrasekaran, Sofie Kjellerup Christensen, Troels Tolstrup Nielsen, Jørgen Nielsen, Poul Hyttel, Martin Røssel Larsen, Helle Waagepetersen, Kristine Karla Freude
Frontotemporal dementia (FTD) is amongst the most prevalent early onset dementias and even though it is clinically, pathologically and genetically heterogeneous, a crucial involvement of metabolic perturbations in FTD pathology is being recognized. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7394b5985fb38fcd8edf51aad2a9bb5
https://doi.org/10.21203/rs.2.23638/v3
https://doi.org/10.21203/rs.2.23638/v3
