Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Martin Piontek"'
Autor:
Jessica Ebner, Johannes Schmoellerl, Martin Piontek, Gabriele Manhart, Selina Troester, Bing Z. Carter, Heidi Neubauer, Richard Moriggl, Gergely Szakács, Johannes Zuber, Thomas Köcher, Michael Andreeff, Wolfgang R. Sperr, Peter Valent, Florian Grebien
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The BCL-2 inhibitor Venetoclax is a promising agent for the treatment of acute myeloid leukemia (AML). However, many patients are refractory to Venetoclax, and resistance develops quickly. ATP-binding cassette (ABC) transporters mediate chem
Externí odkaz:
https://doaj.org/article/c9c4a1f7bca449409f4ee0bf6e5c440b
Autor:
Laura Machin, Martin Piontek, Sara Todhe, Katrin Staniek, Lianet Monzote, Werner Fudickar, Torsten Linker, Lars Gille
Publikováno v:
Molecules, Vol 27, Iss 20, p 6846 (2022)
Leishmaniasis is a vector-borne disease caused by protozoal Leishmania parasites. Previous studies have shown that endoperoxides (EP) can selectively kill Leishmania in host cells. Therefore, we studied in this work a set of new anthracene-derived EP
Externí odkaz:
https://doaj.org/article/90733c19152148ba8a2874239e0a959f
Autor:
Martin Piontek, Dominik Kirchhofer, Lisa Gabler, Daniela Lötsch-Gojo, Christine Pirker, Felix Schmitt-Hoffner, Carola N Jaunecker, Marcel Kool, Walter Berger, Johannes Gojo
Publikováno v:
Neuro-Oncology. 24:i51-i52
BCL-6 transcriptional corepressor (BCOR) is an epigenetic regulator that silences gene expression mainly via the polycomb repressive complex 1.1 (PRC1.1). BCOR genomic alterations are found in a variety of different tumors and recently central nervou
Autor:
Dominik Kirchhofer, Daniela Lötsch-Gojo, Lisa Gabler, Carola N Jaunecker, Martin Piontek, Lisa Mayr, Bernhard Englinger, Christine Pirker, Thomas Mohr, Anna Lämmerer, Felix Schmitt-Hoffner, Bernd Boidol, Stefan Kubiceck, Andreas Peyrl, Amadeo A Azizi, Christian Dorfer, Christine Haberler, Marcel Kool, Walter Berger, Johannes Gojo
Publikováno v:
Neuro-Oncology. 24:i52-i52
Central nervous system (CNS) tumors with BCOR internal tandem duplications (CNS-BCOR ITD) are aggressive malignancies recently included in the 2021 WHO Classification of CNS tumors. This entity is characterized by ITDs within the PUFD domain of BCOR,