Zobrazeno 1 - 10
of 555
pro vyhledávání: '"Martin Pichler"'
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-16 (2024)
Abstract At least 40% of human cancers are associated with aberrant ERK pathway activity (ERKp). Inhibitors targeting various effectors within the ERKp have been developed and explored for over two decades. Conversely, a substantial body of evidence
Externí odkaz:
https://doaj.org/article/4f962fd27221425ba9c49f1e22053cd2
Autor:
Katharina Jonas, Felix Prinz, Manuela Ferracin, Katarina Krajina, Barbara Pasculli, Alexander Deutsch, Tobias Madl, Beate Rinner, Ondrej Slaby, Christiane Klec, Martin Pichler
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-17 (2023)
Abstract Background Triple negative breast cancer (TNBC) is a particularly aggressive and difficult-to-treat subtype of breast cancer that requires the development of novel therapeutic strategies. To pave the way for such developments it is essential
Externí odkaz:
https://doaj.org/article/d088562194214dca97084323852b7d66
Autor:
Matthäus Majewski, Pia Paffenholz, Christian Ruf, Yue Che, Christoph Seidel, Julia Heinzelbecker, Hans‐Ulrich Schmelz, Cord Matthies, Peter Albers, Carsten Bokemeyer, Axel Heidenreich, Martin Pichler, Tim Nestler, the GTCSG (German Testicular Cancer Study Group)
Publikováno v:
Cancer Medicine, Vol 12, Iss 16, Pp 16829-16836 (2023)
Abstract Background Metastatic germ cell tumors of the testis (GCTs) are risk‐stratified according to the International Germ Cell Cancer Collaborative Group (IGCCCG) classification system. This risk classification is based on anatomical risk factor
Externí odkaz:
https://doaj.org/article/20af3c4e291440cab5798b63f736206e
Autor:
Matthias Preusser, Erika Richtig, Florian Moik, Cihan Ay, Martin Pichler, Florian Posch, Armin Gerger, Lukas Koch, Thomas Bauernhofer, Thomas Winder, Dominik A Barth, Sarah Steinlechner, Marie-Christina Mayer, Amelie M Sandner, Franziska Berton, Verena Schlintl, Nikolaus John, Robert Wurm, Patrick Reimann, Christoph Wohlkönig, Philipp J Jost, Angelika Terbuch, Jakob Michael Riedl
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Background C reactive protein (CRP) kinetics have recently been suggested as predictive biomarkers for the efficacy of immune checkpoint inhibitor (ICI) therapy in selected cancer types. The aim of this study was to characterize early CRP kinetics as
Externí odkaz:
https://doaj.org/article/a40a1d9c33b346768e290b28474e9d93
Autor:
Andrea Katharina Lindner, Felizian Lackner, Piotr Tymoszuk, Dominik Andreas Barth, Andreas Seeber, Florian Kocher, Bettina Toth, Margarethe Hochleitner, Martin Pichler, Renate Pichler
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Introduction Clinical trials investigating efficacy of immune checkpoint inhibitors (ICI) revealed sex-specific divergent outcomes in urothelial cancer (UC), suggesting that sex hormones might play an important role in gender-specific dimorp
Externí odkaz:
https://doaj.org/article/f586a4446c9c46e996ae7923030ddea9
Autor:
Andreas Untergasser, Jan Hellemans, Michael W. Pfaffl, Jan M. Ruijter, Maurice J. B. van denHoff, Mihnea P. Dragomir, Douglas Adamoski, Sandra Martha Gomes Dias, Rui Manuel Reis, Manuela Ferracin, Emmanuel Dias‐Neto, Ian Marsh, Mikael Kubista, Muller Fabbri, Ajay Goel, Ondřej Slabý, Erik Knutsen, Baoqing Chen, Massimo Negrini, Koshi Mimori, Martin Pichler, Maria Papatriantafyllou, Simone Anfossi, Thomas D. Schmittgen, Jim Huggett, Stephen Bustin, Jo Vandesompele, George A. Calin, for the HEROIC (tHe initiativE gRoup On qRT dIsClosure) Consortium
Publikováno v:
Molecular Oncology, Vol 17, Iss 5, Pp 713-717 (2023)
Accuracy and transparency of scientific data are becoming more and more relevant with the increasing concern regarding the evaluation of data reproducibility in many research areas. This concern is also true for quantifying coding and noncoding RNAs,
Externí odkaz:
https://doaj.org/article/fc57157ea1114752966f2e759b70680f
Autor:
Isabella Pototschnig, Ursula Feiler, Clemens Diwoky, Paul W. Vesely, Thomas Rauchenwald, Margret Paar, Latifa Bakiri, Laura Pajed, Peter Hofer, Karl Kashofer, Nyamdelger Sukhbaatar, Gabriele Schoiswohl, Thomas Weichhart, Gerald Hoefler, Christoph Bock, Martin Pichler, Erwin F. Wagner, Rudolf Zechner, Martina Schweiger
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 93-107 (2023)
Abstract Background Cancer‐associated cachexia (CAC) is a wasting syndrome drastically reducing efficacy of chemotherapy and life expectancy of patients. CAC affects up to 80% of cancer patients, yet the mechanisms underlying the disease are not we
Externí odkaz:
https://doaj.org/article/562eec85d9b4414fbcf6d13bb3bc9bf1
Autor:
Maria Anna Smolle, Wolfgang Helmberg, Eva Maria Matzhold, Dominik Andreas Barth, Nazanin Sareban, Joanna Szkandera, Bernadette Liegl‐Atzwanger, Andreas Leithner, Martin Pichler
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1237-1246 (2023)
Abstract Background Perioperatively administered (leukocyte reduced) allogeneic red blood cell transfusions (lrRBCTs) may lead to transfusion‐related immunomodulation and reduced overall survival (OS) in cancer patients. Herein, the effect of lrRBC
Externí odkaz:
https://doaj.org/article/c77ed348a92049c6b254dbce1ebdf3e4
Autor:
Felix Prinz, Katharina Jonas, Amar Balihodzic, Christiane Klec, Andreas Reicher, Dominik Andreas Barth, Jakob Riedl, Armin Gerger, Tobias Kiesslich, Christian Mayr, Beate Rinner, Julia Kargl, Martin Pichler
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 1305-1315 (2022)
The microRNA-200 family has wide-ranging regulatory functions in cancer development and progression. Above all, it is strongly associated with the epithelial-to-mesenchymal transition (EMT), a process during which cells change their epithelial to a m
Externí odkaz:
https://doaj.org/article/9edcfdbbce2f49dc9ef762600d2aaea8
Autor:
Katharina Jonas, Felix Prinz, Manuela Ferracin, Katarina Krajina, Alexander Deutsch, Tobias Madl, Beate Rinner, Ondrej Slaby, Christiane Klec, Martin Pichler
Publikováno v:
Non-Coding RNA, Vol 10, Iss 1, p 2 (2023)
MicroRNAs (miRNAs) are crucial post-transcriptional regulators of gene expression, and their deregulation contributes to many aspects of cancer development and progression. Thus, miRNAs provide insight into oncogenic mechanisms and represent promisin
Externí odkaz:
https://doaj.org/article/b8abed994f604fbea7adefc447d9a49c