Zobrazeno 1 - 5
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pro vyhledávání: '"Martin Pfanzelt"'
Publikováno v:
Angewandte Chemie. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5988d5ecc179b402a42fabf8a702204
https://doi.org/10.1002/ange.202201136
https://doi.org/10.1002/ange.202201136
Publikováno v:
Angewandte Chemie. 134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5076abc76e245babae1e8da6e6f05af0
https://doi.org/10.1002/ange.202117724
https://doi.org/10.1002/ange.202117724
Publikováno v:
Angewandte Chemie (International ed. in English). 61(24)
Unprecedented bacterial targets are urgently needed to overcome the resistance crisis. Herein we systematically mine pyridoxal phosphate-dependent enzymes (PLP-DEs) in bacteria to focus on a target class which is involved in crucial metabolic process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb09d0e3783aded9a0460c8fad4b5cb
https://pubmed.ncbi.nlm.nih.gov/35199904
https://pubmed.ncbi.nlm.nih.gov/35199904
Autor:
Sabine Schneider, Nina C. Bach, Matthew B. Nodwell, Martin Pfanzelt, Stephan A. Sieber, Volker C. Kirsch, Matthias Stahl, Annabelle Hoegl
Publikováno v:
Nature Chemistry
Nature chemistry
Nature chemistry
Pyridoxal phosphate (PLP) is an enzyme cofactor required for the chemical transformation of biological amines in many central cellular processes. PLP-dependent enzymes (PLP-DEs) are ubiquitous and evolutionarily diverse, making their classification b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bd7852111b2c60f0fa210467c885b3
Publikováno v:
Angewandte Chemie International Edition. 61(29)
Cofactors are required for almost half of all enzyme reactions, but their functions and binding partners are not fully understood even after decades of research. Functionalised cofactor mimics that bind in place of the unmodified cofactor can provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef8e0d62c6ce03de0022babc1c07a92