Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Martin Pehrsson"'
Autor:
Marta S. Alexdottir, Martin Pehrsson, Viktor Domislovic, Line E. Godskesen, Aleksander Krag, Jens Kjeldsen, Marko Brinar, Ana Barisic, Anne-Christine Bay-Jensen, Morten A. Karsdal, Zeljko Krznaric, Joachim H. Mortensen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Neutrophils play a significant role in sustaining chronic inflammation in Inflammatory Bowel Disease. The intestinal basement membrane acts as a barrier for immunological homeostasis, where the α3 and α4 chains of type IV collagen are expr
Externí odkaz:
https://doaj.org/article/36ce61ebf75c4f13b829c1c0aa30a870
Autor:
Martin Pehrsson, Willemijn E. de Rooij, Anne-Christine Bay-Jensen, Morten Asser Karsdal, Joachim Høg Mortensen, Albert Jan Bredenoord
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/98ec509478f84f17be2615138c8c40dd
Autor:
Martin Pehrsson, Willemijn E. de Rooij, Anne-Christine Bay-Jensen, Morten Asser Karsdal, Joachim Høg Mortensen, Albert Jan Bredenoord
Publikováno v:
BMC Gastroenterology, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Eosinophilic esophagitis (EoE) is a chronic progressive inflammatory disease of the esophagus, characterized by extracellular matrix remodeling and fibrotic stricture formation. Disease monitoring requires multiple re-endoscopies
Externí odkaz:
https://doaj.org/article/0ab13c589f114cf895d2463f8a930d4c
Autor:
Carin Biel, Anniek Kastermans, Janneke Heidema, Martin Pehrsson, Charlotte Henstra, Joachim Mortensen, Klaas Nico Faber, Peter Olinga
Publikováno v:
Cells, Vol 13, Iss 13, p 1084 (2024)
In Crohn’s Disease (CD), intestinal fibrosis is a prevalent yet unresolved complication arising from chronic and transmural inflammation. The histological assessment of CD intestines shows changes in tissue morphology in all the layers, including t
Externí odkaz:
https://doaj.org/article/47dd384992ff487e93c3b4e213ddb9fe
Autor:
Yunyun Luo, Martin Pehrsson, Lasse Langholm, Morten Karsdal, Anne-Christine Bay-Jensen, Shu Sun
Publikováno v:
Diagnostics, Vol 13, Iss 11, p 1835 (2023)
Immunoassays, which have gained popularity in clinical practice and modern biomedical research, play an increasingly important role in quantifying various analytes in biological samples. Despite their high sensitivity and specificity, as well as thei
Externí odkaz:
https://doaj.org/article/5b87b819518e4a70aad33bdfc76a7fee
Autor:
Marta S. Alexdottir, Arno R. Bourgonje, Morten A. Karsdal, Martin Pehrsson, Roberta Loveikyte, Hendrik M. van Dullemen, Marijn C. Visschedijk, Eleonora A. M. Festen, Rinse K. Weersma, Klaas Nico Faber, Gerard Dijkstra, Joachim H. Mortensen
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundCrohn’s disease (CD) is characterized by excessive protease activity and extracellular matrix (ECM) remodeling. To date, 30–50% of patients experience non-response to anti-TNF-α treatment. This study aimed to assess whether serological
Externí odkaz:
https://doaj.org/article/fff2a2308066439c9000ede3fd3ae70f
Autor:
Marta S. Alexdottir, Arno R. Bourgonje, Morten A. Karsdal, Martin Pehrsson, Roberta Loveikyte, Hendrik M. van Dullemen, Marijn C. Visschedijk, Eleonora A. M. Festen, Rinse K. Weersma, Klaas Nico Faber, Gerard Dijkstra, Joachim H. Mortensen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8137 (2022)
Crohn’s disease (CD) is a relapsing-remitting inflammatory disease of the gastrointestinal (GI) tract characterized by increased extracellular matrix (ECM) remodeling. The introduction of the α4β7-integrin inhibitor vedolizumab (VEDO) has improve
Externí odkaz:
https://doaj.org/article/86aec7cd862f4bb7a5aa85eb0a5b04aa
Autor:
Arno R. Bourgonje, Marta S. Alexdottir, Antonius T. Otten, Roberta Loveikyte, Anne‐Christine Bay‐Jensen, Martin Pehrsson, Hendrik M. van Dullemen, Marijn C. Visschedijk, Eleonora A. M. Festen, Rinse K. Weersma, Morten A. Karsdal, Klaas Nico Faber, Joachim H. Mortensen, Gerard Dijkstra
Publikováno v:
Alimentary Pharmacology & Therapeutics, 56(4), 675-693. Wiley
Background: Increased collagen remodelling is a key pathophysiological component underlying intestinal stricture and fistula development in Crohn's disease (CD).Aims: To investigate associations between serological biomarkers of collagen turnover and
Autor:
Anne-Christine Bay-Jensen, Michael J. Davies, Joachim Høg Mortensen, Morten A. Karsdal, Martin Pehrsson, Tina Manon-Jensen
Publikováno v:
Expert Review of Molecular Diagnostics. 21:1049-1064
Introduction: Enzymatic cross-linking of the collagens within the extracellular matrix (ECM) catalyzed by enzymes such as lysyl oxidase (LOX) and lysyl oxidase like-enzymes 1–4 (LOXL), transglutaminase 2 (TG2), and peroxidasin (PXDN) contribute to
Autor:
Martin Pehrsson, Tina Manon‐Jensen, Shu Sun, Ida F. Villesen, Helena Castañé, Jorge Joven, Keyur Patel, Zachary Goodman, Mette J. Nielsen, Anne‐Christine Bay‐Jensen, Diana J. Leeming, Joachim H. Mortensen, Morten A. Karsdal
Publikováno v:
Pehrsson, M, Manon-Jensen, T, Sun, S, Villesen, I F, Castañé, H, Joven, J, Patel, K, Goodman, Z, Nielsen, M J, Bay-Jensen, A C, Leeming, D J, Mortensen, J H & Karsdal, M A 2022, ' An MMP-degraded and cross-linked fragment of type III collagen as a non-invasive biomarker of hepatic fibrosis resolution ', Liver International, vol. 42, no. 7, pp. 1605-1617 . https://doi.org/10.1111/liv.15270
Background and Aims: Liver fibrosis results from a prolonged wound healing response to continued injury with excessive production of extracellular proteins. In patients with chronic liver disease, the monitoring of liver fibrosis dynamics is of high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee5bb795f38b63bce37cfe522ee5cdc4
https://curis.ku.dk/portal/da/publications/an-mmpdegraded-and-crosslinked-fragment-of-type-iii-collagen-as-a-noninvasive-biomarker-of-hepatic-fibrosis-resolution(82cc768a-6c64-49d1-8a6d-5b5ed491575b).html
https://curis.ku.dk/portal/da/publications/an-mmpdegraded-and-crosslinked-fragment-of-type-iii-collagen-as-a-noninvasive-biomarker-of-hepatic-fibrosis-resolution(82cc768a-6c64-49d1-8a6d-5b5ed491575b).html