Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Martin P. Madsen"'
Autor:
Cecilie Hundahl, Petra Kotzbeck, Hayley B. Burm, Søren H. Christiansen, Lola Torz, Aske W. Helge, Martin P. Madsen, Cecilia Ratner, Annette K. Serup, Jonatan J. Thompson, Thomas O. Eichmann, Tune H. Pers, David P.D. Woldbye, Daniele Piomelli, Bente Kiens, Rudolf Zechner, Louise J. Skov, Birgitte Holst
Publikováno v:
Molecular Metabolism, Vol 47, Iss , Pp 101174- (2021)
Objective: The goal of this study was to investigate the importance of central hormone-sensitive lipase (HSL) expression in the regulation of food intake and body weight in mice to clarify whether intracellular lipolysis in the mammalian hypothalamus
Externí odkaz:
https://doaj.org/article/b4e606e56133422d9a7ea2b947c8d458
Autor:
Asbjørn Graver Petersen, Stefanie H. Korntner, Jamal Bousamaki, Denise Oró, Alba Manresa Arraut, Susanne E. Pors, Casper Gravesen Salinas, Maja Worm Andersen, Martin Rønn Madsen, Yaohui Nie, Jordan Butts, Manuel Roqueta‐Rivera, Ulf Simonsen, Henrik H. Hansen, Michael Feigh
Publikováno v:
Physiological Reports, Vol 12, Iss 19, Pp n/a-n/a (2024)
Abstract This study comprehensively validated the bleomycin (BLEO) induced mouse model of IPF for utility in preclinical drug discovery. To this end, the model was rigorously evaluated for reproducible phenotype and TGFβ‐directed treatment outcome
Externí odkaz:
https://doaj.org/article/cb84d450302846dba69d6266991df0ae
Autor:
Mathias Flensted-Jensen, Denise Oró, Emma A. Rørbeck, Chen Zhang, Martin Rønn Madsen, Andreas Nygaard Madsen, Jenny Norlin, Michael Feigh, Steen Larsen, Henrik H. Hansen
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Hepatocellular senescence may be a causal factor in the development and progression of non-alcoholic steatohepatitis (NASH). The most effective currently available treatment for NASH is lifestyle intervention, including dietary mo
Externí odkaz:
https://doaj.org/article/4d0d010b55a64fcf88015bd8b43d2810
Autor:
Henrik H. Hansen, Susanne Pors, Maja W. Andersen, Mogens Vyberg, Jacob Nøhr-Meldgaard, Malte Hasle Nielsen, Denise Oró, Martin Rønn Madsen, Monika Lewinska, Mathias B. Møllerhøj, Andreas Nygaard Madsen, Michael Feigh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Non-alcoholic steatohepatitis (NASH) is emerging as a major cause of hepatocellular carcinoma (HCC), however, it is not resolved if compounds in late-stage clinical development for NASH may have additional therapeutic benefits in NASH-driven
Externí odkaz:
https://doaj.org/article/6927b3ad4ca84f23baf16f380b108cdf
Autor:
Grethe Skovbjerg, Andreas Mæchel Fritzen, Charlotte Sashi Aier Svendsen, Johanna Perens, Jacob Lercke Skytte, Camilla Lund, Jens Lund, Martin Rønn Madsen, Urmas Roostalu, Jacob Hecksher-Sørensen, Christoffer Clemmensen
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101907- (2024)
Objectives: There is significant interest in uncovering the mechanisms through which exercise enhances cognition, memory, and mood, and lowers the risk of neurodegenerative diseases. In this study, we utilize forced treadmill running and distance-mat
Externí odkaz:
https://doaj.org/article/f93ddec9e78a4dd68b8999c8e588f1ac
Autor:
An-Na Moon, François Briand, Natalia Breyner, Dong-Keun Song, Martin Rønn Madsen, Hongbin Kim, Keonwoo Choi, Yoonsuk Lee, Wan Namkung
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116331- (2024)
Farnesoid X receptor (FXR) plays a pivotal role in the regulation of bile acid homeostasis and is involved in the pathogenesis of nonalcoholic steatohepatitis (NASH). Although FXR agonists effectively alleviate pathological features of NASH, adverse
Externí odkaz:
https://doaj.org/article/1a24c1149adb4cefb1cc19199d0981b2
Autor:
Mathias B. Møllerhøj, Sanne S. Veidal, Kirstine Tølbøl Thrane, Denise Oró, Agnete Overgaard, Casper Gravesen Salinas, Martin Rønn Madsen, Larissa Pfisterer, Mogens Vyberg, Eric Simon, Andre Broermann, Niels Vrang, Jacob Jelsing, Michael Feigh, Henrik H. Hansen
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 5, Pp 1167-1186 (2022)
Abstract Non‐alcoholic steatohepatitis (NASH) has emerged as a major challenge for public health because of high global prevalence and lack of evidence‐based therapies. Most animal models of NASH lack sufficient validation regarding disease progr
Externí odkaz:
https://doaj.org/article/5fe3d3005960450b826f54e82c75529a
Publikováno v:
Journal of Innate Immunity, Pp 1-11 (2021)
The hyperinflammatory burden is immense in necrotizing soft-tissue infection (NSTI). The complement system is a key during the innate immune response and may be a promising target to reduce the inflammatory response, potentially improving the clinica
Externí odkaz:
https://doaj.org/article/c6c6a22908c849f5bb910249a1d54395
Autor:
Anna Søndergaard, Martin Korsbak Madsen, Brice Ozenne, Sophia Armand, Gitte Moos Knudsen, Patrick MacDonald Fisher, Dea Siggaard Stenbæk
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
BackgroundPsilocybin-induced mystical-type experiences are associated with lasting positive psychological outcomes. Recent studies indicate that trait mindfulness is increased 3 months after psilocybin intake, preceded by decreases in neocortical ser
Externí odkaz:
https://doaj.org/article/a8431aa8fb25453c942dc767ced87af9
Autor:
Drummond E-Wen McCulloch, Maria Zofia Grzywacz, Martin Korsbak Madsen, Peter Steen Jensen, Brice Ozenne, Sophia Armand, Gitte Moos Knudsen, Patrick MacDonald Fisher, Dea Siggaard Stenbæk
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Psychedelic drugs such as psilocybin have shown substantial promise for the treatment of several psychiatric conditions including mood and addictive disorders. They also have the remarkable property of producing persisting positive psychological chan
Externí odkaz:
https://doaj.org/article/b6868bd75ba5423eba8ec3f8e90b6d18