Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Martin Olomucki"'
Autor:
Bernard Ehresmann, Régine Millon, Jean-Pierre Ebel, Claude Backendorf, Martin Olomucki, Barbara Golinska
Publikováno v:
European Journal of Biochemistry. 115:479-484
The bifunctional reagent ethyl 4-azidobenzoylaminoacetimidate was used to crosslink specifically ribosomal protein S1 to 16-S RNA within 30-S subunits. The reagent was attached to isolated protein S1. The modified protein was reassociated with protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8260a8ab4ee825907d83529d19c9e97
https://doi.org/10.1111/j.1432-1033.1981.tb06227.x
https://doi.org/10.1111/j.1432-1033.1981.tb06227.x
Publikováno v:
The Journal of Organic Chemistry. 57:1579-1585
α-Acetylenic esters are able to react under mild experimental conditions with the base moiety of adenosine and cytidine, while guanosine is unreactive. A double reaction of the triple bond and the ester group of the reagent with the NH 2 group and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a8bce1c80ee006680c1046598b08782
https://doi.org/10.1021/jo00031a045
https://doi.org/10.1021/jo00031a045
Autor:
J. Y. Le Gall, Martin Olomucki
Publikováno v:
Organic Syntheses
Alkoxycarbonylation of propargyl chloride: methyl 4-chloro-2-butynoate product: methyl 4-chloro-2-butynoate product: 4-Chloro-2-butynoic (chlorotetrolic) acid product: ethyl 4-chloro-2-butynoate product: tert-butyl 4-chloro-2-butynoate Keywords: acyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::961fb3f2eba0e47bdcce485ae31e30b9
https://doi.org/10.1002/0471264180.os065.08
https://doi.org/10.1002/0471264180.os065.08
Autor:
Martin Olomucki, Pierre Roques
Publikováno v:
Nucleosides and Nucleotides. 9:455-456
Two isomeric tricyclic adenine derivatives can form by reaction of methyl 4—chloro-2—butynoate with single-stranded nucleic acids, depending on the degree of base stacking. An evaluation of the conformation of the polynucleotide can thus be easil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13e40be1cf684d6fd954aabddae47d7a
https://doi.org/10.1080/07328319008045172
https://doi.org/10.1080/07328319008045172
Publikováno v:
Tetrahedron Letters. 25:3471-3474
The NH2 group and the adjacent ring nitrogen of adenosine and cytidine react with α-acetylenic esters by addition across the triple bond and formation of a lactam with the ester group.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75cf531b6dac19525785250ae92866d4
https://doi.org/10.1016/s0040-4039(01)91050-0
https://doi.org/10.1016/s0040-4039(01)91050-0
Publikováno v:
Bioorganic Chemistry. 10:455-469
A new compound, dithiobis[9-(2-ethylenecarbamoylethylamino)-2,3-dimethoxy-6-azido-acridine], was synthesized and used in some preliminary experiments to form cleavable complexes between nucleic acids and proteins. In a first step the azidoacridine mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f72976f98673f147a3a51e47d471f2c
https://doi.org/10.1016/0045-2068(81)90056-0
https://doi.org/10.1016/0045-2068(81)90056-0
Publikováno v:
Bioorganic Chemistry. 11:262-273
The properties of the chloro- o,o′ -dinitrophenyl group, more suitable as a building block for the design of chromogenic bifunctional protein reagents than the corresponding known o , p derivatives, are investigated by model reactions with small mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d917f12555d66f00baa7f0bcbb331fe8
https://doi.org/10.1016/0045-2068(82)90002-5
https://doi.org/10.1016/0045-2068(82)90002-5
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 951:71-77
The reaction of yeast tRNAPhe with methyl chlorotetrolate, ClCH2-C≡C-COOCH3, was studied. This reagent converts adenine and cytosine rings into derivatives in which an additional heterocycle bearing the alkylating chloromethyl group is fused to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f10fb989f071c53974d2c763d8f1c773
https://doi.org/10.1016/0167-4781(88)90026-7
https://doi.org/10.1016/0167-4781(88)90026-7
Autor:
Martin Olomucki, Jacques Diopoh
Publikováno v:
Bioorganic Chemistry. 11:463-477
The possibility of using the acetylenic function for chemical modification of proteins was tested on chlorotetrolic acid and methyl chlorotetrolate. These compounds react under mild conditions with different functional groups analogous to those prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3e0859e495ba589d2fa534c96cc84eb
https://doi.org/10.1016/0045-2068(82)90038-4
https://doi.org/10.1016/0045-2068(82)90038-4
Autor:
Jacques Diopoh, Martin Olomucki
Publikováno v:
Hoppe-Seyler´s Zeitschrift für physiologische Chemie. 360:1257-1262
Ethyl bromoacetimidate was designed as a potential reagent for cross-linking protein NH2 groups with a vicinal nucleophile. The chemical properties of this compound were studied by model reactions with small molecules. Ethyl bromoacetimidate amidinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2238d7846cbe5b8044242d220609ffb6
https://doi.org/10.1515/bchm2.1979.360.2.1257
https://doi.org/10.1515/bchm2.1979.360.2.1257