Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Martin O, Spycher"'
Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates
Autor:
Cédric Vonarburg, Marius Loetscher, Martin O. Spycher, Alain Kropf, Marlies Illi, Sharon Salmon, Sean Roberts, Karin Steinfuehrer, Ian Campbell, Sandra Koernig, Joseph Bain, Monika Edler, Ulrich Baumann, Sylvia Miescher, Dennis W. Metzger, Alexander Schaub, Fabian Käsermann, Adrian W. Zuercher
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-16 (2019)
Abstract Background Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin serum levels. Interestingly, patients with Chronic Obstructive Pulmonary Dise
Externí odkaz:
https://doaj.org/article/14ff40a2a8dd402c98faa7221f7dd197
Autor:
Marilyn Marrari, Christopher R. Ensor, Adriana Zeevi, Massimo Mangiola, Martin O. Spycher, M. Berger
Publikováno v:
Transplantation. 102:2126-2132
Background Human immunoglobulins (H-Ig) are widely used in solid organ transplantation for immunoglobulin G (IgG) replacement and for desensitization and treatment of antibody-mediated rejection. They are obtained from plasma pools and may contain HL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2563c2315aa9f6595a4741f3833cf153
https://doi.org/10.1097/tp.0000000000002312
https://doi.org/10.1097/tp.0000000000002312
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71235 (2013)
An anti-inflammatory effect of reconstituted High Density Lipoprotein (rHDL) has been demonstrated in atherosclerosis and in sepsis models. An increase of adhesion molecules as well as tissue factor expression on endothelial cells in response to infl
Externí odkaz:
https://doaj.org/article/37636a35f42640baa747ea7459c0f7ce
Autor:
Alphonse Hubsch, Abdulgabar Salama, Stefano Fontana, Orell Mielke, Vesselina Goranova-Marinova, Sandra Wymann, Billie L. Durn, Martin O. Spycher, John P. Lawo, Amgad Shebl
Publikováno v:
Transfusion. 57:2629-2638
BACKGROUND Patients treated with intravenous immunoglobulins (IVIG) rarely experience symptomatic hemolysis. Although anti-A and anti-B isoagglutinins from the product are involved in most cases, the actual mechanisms triggering hemolysis are unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e75242fe10184069364ce48c801e57
https://doi.org/10.1111/trf.14289
https://doi.org/10.1111/trf.14289
Topical application of nebulized human IgG, IgA and IgAM in the lungs of rats and non-human primates
Autor:
Adrian Zuercher, Sean Roberts, Joseph Bain, Dennis W. Metzger, Fabian Käsermann, Alain Kropf, Marlies Illi, Marius Loetscher, Monika Edler, Karin Steinfuehrer, Sandra Koernig, Sylvia Miescher, Ulrich Baumann, Alexander Schaub, Martin O. Spycher, Sharon L. Salmon, Ian K. Campbell, Cédric Vonarburg
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-16 (2019)
Respiratory Research
Respiratory Research
Background Recurrent and persistent infections are known to affect airways of patients with Primary Immunodeficiency despite appropriate replacement immunoglobulin serum levels. Interestingly, patients with Chronic Obstructive Pulmonary Disease or wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb9756a20139aa9fd30fc2462510ccc
https://doi.org/10.1186/s12931-019-1057-3
https://doi.org/10.1186/s12931-019-1057-3
Autor:
Mitchell J. de Souza, Matthew P. Hardy, Martin J. Pearse, Kim G. Lieu, Saw Yen Ow, Martin O. Spycher, Anup G. Nair, Michael J. Wilson, Jason Simmonds, Yun Dai, Sandra Wymann, Adrian Zuercher, Anna Schnell, Con Panousis, Rebecca E. Butcher, Glenn A. Powers, Marcel Mischnik, Tony Rowe, Genevieve Martin-Roussety, Adriana Baz Morelli, Helen Cao, David Leong, Shirley Taylor
Publikováno v:
The Journal of Biological Chemistry
Human complement receptor 1 (HuCR1) is a pivotal regulator of complement activity, acting on all three complement pathways as a membrane-bound receptor of C3b/C4b, C3/C5 convertase decay accelerator, and cofactor for factor I-mediated cleavage of C3b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::605c43f8a6fc70ffcd57fb8866f643b1
https://doi.org/10.1074/jbc.ra120.016127
https://doi.org/10.1074/jbc.ra120.016127
Autor:
Martin O. Spycher, Andreas Gille, Svetlana A Didichenko, Alexandre M.O. Cukier, Alexei V Navdaev, Patrick Schuetz, M. John Chapman, Samuel D. Wright, Anatol Kontush, Patrice Thérond
Publikováno v:
Circulation Research. 119:751-763
Rationale: CSL112, human apolipoprotein A-I (apoA-I) reconstituted with phosphatidylcholine, is known to cause a dramatic rise in small high-density lipoprotein (HDL). Objective: To explore the mechanisms by which the formation of small HDL particles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad48bbedb4175c4a1ae48e37431b722
https://doi.org/10.1161/circresaha.116.308685
https://doi.org/10.1161/circresaha.116.308685
Autor:
Martin Imboden, Liane Hoefferer, Adriano Marques Antunes, Annette Gaida, Isabelle Glauser, Brigitte Siani, Ibrahim El Menyawi, Reinhard Bolli, Katharina Willimann, Eleonora Widmer, Sandra Wymann, Martin O. Spycher
Publikováno v:
Transfusion. 55:S117-S121
BACKGROUND The passive transfer of antibodies specific to blood groups A and B (also called isoagglutinins) contained in immunoglobulin (Ig)G products for intravenous administration (IVIG) is believed to be largely responsible for rare but sometimes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b64557d01dabf20df687e12c73969ae8
https://doi.org/10.1111/trf.13088
https://doi.org/10.1111/trf.13088
Autor:
Rolf Spirig, Adrian Zuercher, Bonnie J. B. Lewis, Jenny Chia, Jason Simmonds, Ian K. Campbell, Tony Rowe, Andreas Hofmann, Donald R. Branch, David Leong, Martin O. Spycher, Chao-Guang Chen, Louis Fabri, Monika Jordi, Con Panousis, Shirley Taylor, Ineke L. Muir, Jennifer Brasseit, Fabian Käsermann, Sandra Koernig, Rebecca E. Butcher, Peter Schmidt, Adriana Baz Morelli, Susann Cattepoel, Pierre Scotney
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 200(8)
Activation of Fc receptors and complement by immune complexes is a common important pathogenic trigger in many autoimmune diseases and so blockade of these innate immune pathways may be an attractive target for treatment of immune complex-mediated pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa3a7164c9d87af7b6e29ca887ff09b
https://pubmed.ncbi.nlm.nih.gov/29760434
https://pubmed.ncbi.nlm.nih.gov/29760434
Autor:
Orell, Mielke, Stefano, Fontana, Vesselina, Goranova-Marinova, Amgad, Shebl, Martin O, Spycher, Sandra, Wymann, Billie L, Durn, John P, Lawo, Alphonse, Hubsch, Abdulgabar, Salama
Publikováno v:
Transfusion. 57(11)
Patients treated with intravenous immunoglobulins (IVIG) rarely experience symptomatic hemolysis. Although anti-A and anti-B isoagglutinins from the product are involved in most cases, the actual mechanisms triggering hemolysis are unclear.A prospect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6d3d0d2c921d0b8725d9ebfcb4890753
https://pubmed.ncbi.nlm.nih.gov/28840942
https://pubmed.ncbi.nlm.nih.gov/28840942