Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Martin Nylöf"'
Autor:
Mickaël Maudet, Jennifer M. A. Laird, Ronald Zemribo, Paul Jones, Michael Dabrowski, Andis Slaitas, Yevgeni Besidski, Gitte Terp, Karin Kolmodin, Andrea Penwell, Andrew Griffin, Didier Rotticci, Anna K. Sundgren-Andersson, Christopher Walpole, Dean Johnson, Alexander Munro, Yin Hu, Therese Lundström, Maryse Labarre, Inger Kers, Huascar Villanueva, Johan Bylund, Martin Nylöf, Mats Svensson, Denis Labrecque, Magali Harter, Sandrine Leclerc, William Brown, Sophie Dautrey, Shawn Johnstone, John Martino, Lucy Horoszok
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:6205-6211
Benzothiazole amides were identified as TRPV1 antagonists from high throughput screening using recombinant human TRPV1 receptor and structure-activity relationships were explored to pinpoint key pharmacophore interactions. By increasing aqueous solub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5999ae8c775dbcf4f87b0f920411e95
https://doi.org/10.1016/j.bmcl.2012.08.018
https://doi.org/10.1016/j.bmcl.2012.08.018
Autor:
Lars Sandberg, Gabor Csjernyik, Anders B. Eriksson, Elisabet Venyike, Martin Nylöf, Karin Skogholm, Yevgeni Besidski, Per-Eric Lund, Inger Kers, Sandra Oerther, Tjerk Bueters, Istvan Macsari, Jan-Erik Nyström
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(17)
Recent findings showing a relation between mutations in the NaV1.7 channel in humans and altered pain sensation has contributed to increase the attractiveness of this ion channel as target for development of potential analgesics. Amido chromanes 1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a998c213802b822708fbf6a9a607adc
https://pubmed.ncbi.nlm.nih.gov/22832315
https://pubmed.ncbi.nlm.nih.gov/22832315
Autor:
Stefan von Berg, Alfredo Giménez-Cassina, Yvonne Nilsson, Félix Hernández, Thomas Borgegård, Sven Hellberg, Ann-Cathrin Radesäter, Javier Díaz-Nido, Per-Olof Markgren, Jesús Avila, Yafeng Xue, Ratan Bhat, Martin Nylöf, Mats Ormö, José J. Lucas, Eva Jerning
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been implicated in pathological conditions such as diabetes and Alzheimer's disease. We report the characterization of a GSK3 inhibitor, AR-A014418, which inhibits GSK3 (IC50 = 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3603bf0acc51f06d47e3f21663b52801
http://hdl.handle.net/10261/251570
http://hdl.handle.net/10261/251570
Autor:
Rolf Johansson, Lars Johansson, Ingeborg Csöregh, Martin Nylöf, Sverker Hanson, Nina Mohell, Eva Hammarberg, Bo-Ragnar Tolf, Charlotte Ahlgren, Anita Westlind-Danielsson, Gun Torell Svantesson, Robert Leideborg, Gunnar Nordvall, Eva Jerning, Seth-Olov Thorberg
Publikováno v:
Journal of medicinal chemistry. 43(15)
A series of new enantiomerically pure 3-amino-3,4-dihydro-2H-1-benzopyrans (3-aminochromans) has been synthesized from (R)- and (S)-5-methoxy-3-amino-3,4-dihydro-2H-1-benzopyran. The absolute configuration of the respective (R)- and (S)-enantiomers w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c14c99657cc620a84c524d93ec8c1e2
https://pubmed.ncbi.nlm.nih.gov/10956192
https://pubmed.ncbi.nlm.nih.gov/10956192
Publikováno v:
European Neuropsychopharmacology. 11:S213-S214
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59fe1430c82e5aa812a9ca3dc3963ef2
https://doi.org/10.1016/s0924-977x(01)80198-x
https://doi.org/10.1016/s0924-977x(01)80198-x