Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Martin Mynář"'
Autor:
Shweta Godbole, Hannah Voß, Antonia Gocke, Simon Schlumbohm, Yannis Schumann, Bojia Peng, Martin Mynarek, Stefan Rutkowski, Matthias Dottermusch, Mario M. Dorostkar, Andrey Korshunov, Thomas Mair, Stefan M. Pfister, Marcel Kwiatkowski, Madlen Hotze, Philipp Neumann, Christian Hartmann, Joachim Weis, Friederike Liesche-Starnecker, Yudong Guan, Manuela Moritz, Bente Siebels, Nina Struve, Hartmut Schlüter, Ulrich Schüller, Christoph Krisp, Julia E. Neumann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and clinically heterogenous. The application of omics technologies—mainly studying nucleic acids—has significantly improved MB classification and stratifica
Externí odkaz:
https://doaj.org/article/675fc26a61af443188a119d2062987c2
Autor:
Melanie Schoof, Shweta Godbole, Thomas K. Albert, Matthias Dottermusch, Carolin Walter, Annika Ballast, Nan Qin, Marlena Baca Olivera, Carolin Göbel, Sina Neyazi, Dörthe Holdhof, Catena Kresbach, Levke-Sophie Peter, Gefion Dorothea Epplen, Vanessa Thaden, Michael Spohn, Mirjam Blattner-Johnson, Franziska Modemann, Martin Mynarek, Stefan Rutkowski, Martin Sill, Julian Varghese, Ann-Kristin Afflerbach, Alicia Eckhardt, Daniel Münter, Archana Verma, Nina Struve, David T. W. Jones, Marc Remke, Julia E. Neumann, Kornelius Kerl, Ulrich Schüller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Pediatric high-grade gliomas of the subclass MYCN (HGG-MYCN) are highly aggressive tumors frequently carrying MYCN amplifications, TP53 mutations, or both alterations. Due to their rarity, such tumors have only recently been identified as a
Externí odkaz:
https://doaj.org/article/09d9e0ef2e924a438dede74c6b3805ed
Autor:
Viktoria L. E. Funke, Sarah Sandmann, Viktoria Melcher, Jochen Seggewiss, Judit Horvath, Natalie Jäger, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Till Milde, Stefan Rutkowski, Martin Mynarek, Julian Varghese, Ronald Sträter, Stephan Rust, Anja Seelhöfer, Janine Reunert, Barbara Fiedler, Ulrich Schüller, Thorsten Marquardt, Kornelius Kerl
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-4 (2023)
Abstract To date, several studies on genomic events underlying medulloblastoma (MB) biology have expanded our understanding of this tumour entity and led to its division into four groups—WNT, SHH, group 3 (G3) and group 4 (G4). However, there is li
Externí odkaz:
https://doaj.org/article/4d42ac6cc3f343f1a26382b1265c71a1
Autor:
Viktoria L. E. Funke, Carolin Walter, Viktoria Melcher, Lanying Wei, Sarah Sandmann, Marc Hotfilder, Julian Varghese, Natalie Jäger, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Till Milde, Martin Mynarek, Stefan Rutkowski, Jochen Seggewiss, Daniela Jeising, Flavia W. de Faria, Thorsten Marquardt, Thomas K. Albert, Ulrich Schüller, Kornelius Kerl
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Cancer metabolism influences multiple aspects of tumorigenesis and causes diversity across malignancies. Although comprehensive research has extended our knowledge of molecular subgroups in medulloblastoma (MB), discrete analysis
Externí odkaz:
https://doaj.org/article/293ede42057e4448bff90666e15848b1
Autor:
Meryem H. Cetin, Thorsten Rieckmann, Konstantin Hoffer, Britta Riepen, Sabrina Christiansen, Fruzsina Gatzemeier, Simon Feyerabend, Melanie Schoof, Ulrich Schüller, Cordula Petersen, Martin Mynarek, Kai Rothkamm, Malte Kriegs, Nina Struve
Publikováno v:
Radiation Oncology, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background The gene of the Epidermal growth factor receptor (EGFR) is one of the most frequently altered genes in glioblastoma (GBM), with deletions of exons 2–7 (EGFRvIII) being amongst the most common genomic mutations. EGFRvIII is heter
Externí odkaz:
https://doaj.org/article/465e6b79a1ff4eba9893278ef9efb89a
Autor:
Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David E. Reuss, Mirjam Blattner, Barbara Worst, Christoph E. Heilig, Katja Beck, Peter Horak, Simon Kreutzfeldt, Elke Paff, Sebastian Stark, Pascal Johann, Florian Selt, Jonas Ecker, Dominik Sturm, Kristian W. Pajtler, Annekathrin Reinhardt, Annika K. Wefers, Philipp Sievers, Azadeh Ebrahimi, Abigail Suwala, Francisco Fernández-Klett, Belén Casalini, Andrey Korshunov, Volker Hovestadt, Felix K. F. Kommoss, Mark Kriegsmann, Matthias Schick, Melanie Bewerunge-Hudler, Till Milde, Olaf Witt, Andreas E. Kulozik, Marcel Kool, Laura Romero-Pérez, Thomas G. P. Grünewald, Thomas Kirchner, Wolfgang Wick, Michael Platten, Andreas Unterberg, Matthias Uhl, Amir Abdollahi, Jürgen Debus, Burkhard Lehner, Christian Thomas, Martin Hasselblatt, Werner Paulus, Christian Hartmann, Ori Staszewski, Marco Prinz, Jürgen Hench, Stephan Frank, Yvonne M. H. Versleijen-Jonkers, Marije E. Weidema, Thomas Mentzel, Klaus Griewank, Enrique de Álava, Juan Díaz Martín, Miguel A. Idoate Gastearena, Kenneth Tou-En Chang, Sharon Yin Yee Low, Adrian Cuevas-Bourdier, Michel Mittelbronn, Martin Mynarek, Stefan Rutkowski, Ulrich Schüller, Viktor F. Mautner, Jens Schittenhelm, Jonathan Serrano, Matija Snuderl, Reinhard Büttner, Thomas Klingebiel, Rolf Buslei, Manfred Gessler, Pieter Wesseling, Winand N. M. Dinjens, Sebastian Brandner, Zane Jaunmuktane, Iben Lyskjær, Peter Schirmacher, Albrecht Stenzinger, Benedikt Brors, Hanno Glimm, Christoph Heining, Oscar M. Tirado, Miguel Sáinz-Jaspeado, Jaume Mora, Javier Alonso, Xavier Garcia del Muro, Sebastian Moran, Manel Esteller, Jamal K. Benhamida, Marc Ladanyi, Eva Wardelmann, Cristina Antonescu, Adrienne Flanagan, Uta Dirksen, Peter Hohenberger, Daniel Baumhoer, Wolfgang Hartmann, Christian Vokuhl, Uta Flucke, Iver Petersen, Gunhild Mechtersheimer, David Capper, David T. W. Jones, Stefan Fröhling, Stefan M. Pfister, Andreas von Deimling
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Sarcomas are morphologically heterogeneous tumours rendering their classification challenging. Here the authors developed a classifier using DNA methylation data from several soft tissue and bone sarcoma subtypes, which has the potential to improve c
Externí odkaz:
https://doaj.org/article/c88e43d5043848c8bc27777e780e6d5b
Autor:
Katja Kloth, Denise Obrecht, Dominik Sturm, Torsten Pietsch, Monika Warmuth-Metz, Brigitte Bison, Martin Mynarek, Stefan Rutkowski
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Gorlin syndrome is a genetic condition associated with the occurrence of SHH activated medulloblastoma, basal cell carcinoma, macrocephaly and other congenital anomalies. It is caused by heterozygous pathogenic variants in PTCH1 or SUFU. In this stud
Externí odkaz:
https://doaj.org/article/2ee8156c703b490f85d58c2bffe999f5
Publikováno v:
METAL 2020 Conference Proeedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f47d5ae40c7f5c21d841eef9339320c
https://doi.org/10.37904/metal.2020.3638
https://doi.org/10.37904/metal.2020.3638
Autor:
Pavel Doležel, Cesare Comicioli, Vladimı́r Kolařı́k, Martin Vondráček, Jiřı́ Slezák, Radovan Vašina, Martin Mynář, Kevin C. Prince, Vladimír Cháb
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. :561-564
A plane grating monochromator based on the SX-700 concept has been constructed for the Materials Science Beamline, Elettra, which is attached to a bending magnet. The tuning range is from 35 to 800 eV with calculated spectral resolving power e/Δe be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7885d8983441b0ea5b4965733dbd5e8
https://doi.org/10.1016/s0168-9002(01)00412-0
https://doi.org/10.1016/s0168-9002(01)00412-0
Autor:
Stephanie T. Jünger, Martin Mynarek, Inken Wohlers, Evelyn Dörner, Anja zur Mühlen, Natalia Velez-Char, Katja von Hoff, Stefan Rutkowski, Monika Warmuth-Metz, Rolf-Dieter Kortmann, Beate Timmermann, Sven Rahmann, Ludger Klein-Hitpass, Andre O. von Bueren, Torsten Pietsch
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Introduction Risk stratification of children with ependymomas of the posterior fossa in current therapeutic protocols is mainly based on clinical criteria. We aimed to identify independent outcome predictors for this disease entity by a syst
Externí odkaz:
https://doaj.org/article/b6f10fd32cfe498ea52b2120536a0527