Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Martin Muik"'
Autor:
Marc Fahrner, Michael Stadlbauer, Martin Muik, Petr Rathner, Peter Stathopulos, Mitsu Ikura, Norbert Müller, Christoph Romanin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Stormorken syndrome is associated with the R304W mutation in STIM1, which is a Calcium sensor in the endoplasmic reticulum. Here authors use FRET and electrophysiology to show that R304W induces STIM1 conformational extension by a dual mechanism resu
Externí odkaz:
https://doaj.org/article/f3d205c02ef7403b8fda99785e3df276
Autor:
Carmen Höglinger, Marc Fahrner, Isabella Derler, Herwig Grabmayr, Martin Muik, Heinrich Krobath, Lena Maltan, Christoph Romanin, Ferdinand Horvath, Adéla Tiffner, Thomas Renger
Publikováno v:
Cellular and Molecular Life Sciences
The calcium release-activated calcium (CRAC) channel consists of STIM1, a Ca2+ sensor in the endoplasmic reticulum (ER), and Orai1, the Ca2+ ion channel in the plasma membrane. Ca2+ store depletion triggers conformational changes and oligomerization
Autor:
Peter B. Stathopulos, Marc Fahrner, Norbert Müller, Mitsu Ikura, Christoph Romanin, Michael Stadlbauer, Petr Rathner, Martin Muik
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
STIM1 and Orai1 are key components of the Ca2+-release activated Ca2+ (CRAC) current. Orai1, which represents the subunit forming the CRAC channel complex, is activated by the ER resident Ca2+ sensor STIM1. The genetically inherited Stormorken syndro
Autor:
Wolfgang Buchberger, Gernot M. Wallner, David Nitsche, Michael K. Grabmann, Christoph Romanin, Leila Maringer, Martin Muik
Publikováno v:
International Journal of Polymer Analysis and Characterization. 22:692-698
Within this work, a fluorescence microscopy approach for the investigation of the distribution of polymer additives in polypropylene is presented. The fluorescent whitening agent 2,5-bis-(5-tert-butyl-benzoxazol-2-yl)-thiophene was used as a model co
Autor:
Carmen, Butorac, Martin, Muik, Isabella, Derler, Michael, Stadlbauer, Victoria, Lunz, Adéla, Krizova, Sonja, Lindinger, Romana, Schober, Irene, Frischauf, Rajesh, Bhardwaj, Matthias A, Hediger, Klaus, Groschner, Christoph, Romanin
Publikováno v:
Cell calcium. 79
Calcium signalling through store-operated calcium (SOC) entry is of crucial importance for T-cell activation and the adaptive immune response. This entry occurs via the prototypic Ca
Autor:
Juan A. Rosado, Irene Frischauf, Esther Lopez, Ginés M. Salido, Tarik Smani, Carlos Cantonero, Isaac Jardin, Martin Muik, Pedro C. Redondo, Isabella Derler
Publikováno v:
Journal of Cell Science.
Stromal interaction molecule 1 (STIM1) is one of the key elements for the activation of store-operated Ca2+ entry (SOCE). Hence, identification of the relevant phosphorylatable STIM1 residues with a possible role in the regulation of STIM1 function a
Autor:
Esther, Lopez, Irene, Frischauf, Isaac, Jardin, Isabella, Derler, Martin, Muik, Carlos, Cantonero, Gines M, Salido, Tarik, Smani, Juan A, Rosado, Pedro C, Redondo
Publikováno v:
Journal of cell science. 132(10)
Stromal interaction molecule 1 (STIM1) is one of the key elements for the activation of store-operated Ca
Autor:
Sabrina Cappello, Anna Hochreiter, Ivan Bogeski, Irene Frischauf, Laura Tociu, Rüdiger Ettrich, Rainer Schindl, Christoph Romanin, Vasilina Zayats, Victoria Lunz, Martin Muik, Klaus Groschner, Amrutha Stallinger, Monika Litviňuková, Teresa Pammer, David Reha, Romana Schober, Daniel Bonhenry, Barbora Svobodova, Carmen Butorac
Publikováno v:
Science signaling. 10(507)
The channel Orai1 requires Ca2+ store depletion in the endoplasmic reticulum and an interaction with the Ca2+ sensor STIM1 to mediate Ca2+ signaling. Alterations in Orai1-mediated Ca2+ influx have been linked to several pathological conditions includ
Autor:
Mate Maus, Stephan Ehl, Martin Muik, Sebastian Fuchs, Peter B. Stathopulos, Christoph Romanin, Murali Prakriya, Amit Jairaman, Mitsuhiko Ikura, Stefan Feske, Melina J. Benson, Marc Fahrner, Carl Weidinger
Publikováno v:
Proceedings of the National Academy of Sciences. 112:6206-6211
Store-operated Ca(2+) entry (SOCE) is a universal Ca(2+) influx pathway that is important for the function of many cell types. SOCE occurs upon depletion of endoplasmic reticulum (ER) Ca(2+) stores and relies on a complex molecular interplay between
Publikováno v:
Advances in experimental medicine and biology. 993
A primary Ca