Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Martin Meng"'
Autor:
Mariana Haeberer, Martin Mengel, Rong Fan, Marina Toquero-Asensio, Alejandro Martin-Toribio, Qing Liu, Yongzheng He, Sonal Uppal, Silvia Rojo-Rello, Marta Domínguez-Gil, Cristina Hernán-García, Virginia Fernández-Espinilla, Caihua Liang, Elizabeth Begier, Javier Castrodeza Sanz, José M. Eiros, Ivan Sanz-Muñoz
Publikováno v:
Infectious Diseases and Therapy, Vol 13, Iss 9, Pp 1983-1999 (2024)
Abstract Introduction We aimed to describe the risk profile of respiratory syncytial virus (RSV) infections among adults ≥ 60 years in Valladolid from January 2010 to August 2022, and to compare them with influenza and COVID-19 controls. Methods Th
Externí odkaz:
https://doaj.org/article/7fc09ac3b8824803a090a6f5eac3ff29
Autor:
Kerstin C. Reuter, Abderraouf Selmi, Christoph Huber, Sebastian Attig, Carmen Loquai, Peter Langguth, Andreas Kuhn, Özlem Türeci, Fulvia Vascotto, Heinrich Haas, Stephan Grabbe, Hossam Hefesha, Martin Meng, Yves Hüsemann, Sebastian Kreiter, Lena M. Kranz, Jessica C. Hassel, Ugur Sahin, Jan Diekmann, Janina Buck, Richard Rae, Mathias Vormehr, Mustafa Diken, Evelyna Derhovanessian, Robert A. Jabulowsky, Sandra Heesch, Christian Grunwitz, Daniel Fritz
Publikováno v:
Nature. 534:396-401
Lymphoid organs, in which antigen presenting cells (APCs) are in close proximity to T cells, are the ideal microenvironment for efficient priming and amplification of T-cell responses. However, the systemic delivery of vaccine antigens into dendritic
Autor:
Sonja Witzel, Leonard Kaps, Tim Beissert, Christian Grunwitz, Yasmin Abassi, Patricia Gomes, Heinrich Haas, Sebastian Rosigkeit, Geethanjali Pickert, Fulvia Vascotto, Martin Meng, Jasmin Röder, Andreas Kuhn, Mustafa Diken, Andreas Kreft, Rosario Heck, Ugur Sahin, Nina Hayduk, Detlef Schuppan, Kira Ziegler, Ernesto Bockamp
Publikováno v:
Molecular pharmaceutics. 15(9)
Targeting mRNA to eukaryotic cells is an emerging technology for basic research and provides broad applications in cancer immunotherapy, vaccine development, protein replacement, and in vivo genome editing. Although a plethora of nanoparticles for ef
Autor:
Funda Meric-Bernstam, Ly M. Nguyen, Siqing Fu, Manuel Schmidt, David S. Hong, Matthew J. Reilley, Timothy A. Yap, Casey R. Ager, Priyamvada Jayaprakash, Sarina Anne Piha-Paul, Michael A. Curran, Matthias Baumann, Jordi Rodon, Martin Meng, Apostolia Maria Tsimberidou, Aung Naing
Publikováno v:
Journal of Clinical Oncology. 37:TPS2669-TPS2669
TPS2669 Background: Drugs targeting pathogen associated molecular patterns are an attractive strategy to stimulate the immune system. Toll-like receptors (TLR) have generated significant interest as an effective means of stimulating the immune system
Autor:
Evelyna Derhovanessian, Christine Anft, Özlem Türeci, Roland Kaufmann, Sebastian Attig, Andreas Kuhn, Martin Meng, Stephan Grabbe, Richard Rae, Christoph Huber, Malte Stein, Felicitas Müller, Andreas Pinter, Fatih Sari, Robert A. Jabulowsky, Mustafa Diken, Alexandra Deubel, Peter Langguth, Doreen Schwarck-Kokarakis, Daniel Maurus, Claudia Guertler, Ludwig Heesen, Katharina H Schreeb, Dirk Jäger, Heidrun Mitzel-Rink, Alexandra Kemmer-Brück, Christoffer Gebhardt, Sebastian Kreiter, Klaus Kuehlcke, Ulrich Luxemburger, Jochen Utikal, Ugur Sahin, Maike Gold, Jessica C. Hassel, Heinrich Haas, Carmen Loquai, Lena M. Kranz
Publikováno v:
Cancer Research. 78:CT156-CT156
Therapeutic vaccination with tumor antigen-encoding RNAs is being investigated in various clinical trials. Typically, the RNA vaccine is administered intradermally, subcutaneously or intranodally with the intention to get expression of the encoded an
Autor:
Stephan Grabbe, Jan Diekmann, Christoph Huber, K Hartmann, Sebastian Attig, Jochen Utikal, Sebastian Kreiter, Peter Langguth, Andreas Kuhn, Carmen Loquai, Doreen Schwarck-Kokarakis, Martin Meng, Malte Stein, Robert A. Jabulowsky, Alexandra Kemmer-Brueck, Heinrich Haas, Mustafa Diken, Ugur Sahin, Klaus Kuehlcke, Oezlem Tuereci, Richard Rae, Lena M. Kranz, Jessica C. Hassel, Janina Buck, Christine Anft, Roland Kaufmann, Evelyna Derhovanessian, Daniel Fritz, Ulrich Luxemburger, Fatih Sari
Publikováno v:
Cancer Research. 77:CT034-CT034
Therapeutic vaccination with tumor antigen-encoding RNAs by local administration is currently being successfully employed in various clinical trials. Advancing from local to more efficient systemic targeting of antigen-presenting cells (APCs), we hav
Autor:
Jan Diekmann, Daniel Fritz, Richard Rae, Robert A. Jabulowsky, Martin Meng, Evelyna Derhovanessian, Stephan Grabbe, Janina Buck, Sebastian Attig, Peter Langguth, Kerstin C. Reuter, Ugur Sahin, Christoph Huber, Abderraouf Selmi, Carmen Loquai, Sandra Heesch, Andreas Kuhn, Fulvia Vascotto, Jessica C. Hassel, Sebastian Kreiter, Heinrich Haas, Özlem Türeci, Hossam Hefesha, Lena M. Kranz, Mathias Vormehr, Mustafa Diken, Yves Hüsemann, Christian Grunwitz
Publikováno v:
Cancer Immunology Research. 4:A004-A004
Mechanisms of antiviral host defense are important for survival and evolutionarily optimized for high sensitivity and potency. Intending to harvest the multitude of highly specialized and intertwined pathogen immune defense programs for cancer immuno
Publikováno v:
Small. 4:1040-1042
Publikováno v:
Synthesis. 2007:348-350
A new and convenient method is presented for the synthesis of mono-2-(p-tolylsulfonyl)-β-cyclodextrin under aqueous conditions that does not require large amounts of polar organic solvents such as DMF, metal-containing reagents such as dibutyltin ox
Autor:
Daniel Fritz, Doreen Schwarck-Kokarakis, Nicole Bidmon, Ulrich Luxemburger, Klaus Kuehlcke, Richard Rae, Sebastian Attig, Fatih Sari, Oezlem Tuereci, Kristina Spieß, Sebastian Kreiter, Andreas Kuhn, Christine Seck, Jochen Utikal, Peter Langguth, Janina Buck, Meike Witt, Alexandra Kemmer-Brueck, Heinrich Haas, Martin Meng, Felicitas Mueller, Ugur Sahin, Mustafa Diken, Evelyna Derhovanessian, Lena M. Kranz, Veronika Jahndel, Jan Diekmann, Christoph Huber, Jessica C. Hassel, Carmen Loquai, Roland Kaufmann, Robert A. Jabulowsky
Publikováno v:
Cancer Research. 76:CT032-CT032
Immunotherapeutic approaches have evolved as promising and valid alternatives to available conventional cancer treatments. Amongst others, vaccination with tumor antigen-encoding RNAs by local administration is currently successfully employed in vari