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pro vyhledávání: '"Martin Matwiejuk"'
Autor:
Stine Dam Jepsen, Astrid Lund, Martin Matwiejuk, Lars Andresen, Kristine Rothaus Christensen, Søren Skov
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Human milk oligosaccharides (HMOs) are present in high numbers in milk of lactating women. They are beneficial to gut health and the habitant microbiota, but less is known about their effect on cells from the immune system. In this study, we investig
Externí odkaz:
https://doaj.org/article/e5134ac8260f4efbabde564aa00ca209
Autor:
Marlene Vuillemin, Jesper Holck, Martin Matwiejuk, Eduardo S. Moreno Prieto, Jan Muschiol, Dora Molnar-Gabor, Anne S. Meyer, Birgitte Zeuner
Publikováno v:
Applied Sciences, Vol 11, Iss 23, p 11493 (2021)
The lacto-N-biosidase LnbB from Bifidobacterium bifidum JCM 1254 was engineered to improve its negligible transglycosylation efficiency with the purpose of enzymatically synthesizing lacto-N-tetraose (LNT; Gal-β1,3-GlcNAc-β1,3-Gal-β1,4-Glc) in one
Externí odkaz:
https://doaj.org/article/7942c6cd56aa423dbdc1d68c9884bde3
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 8, Iss 1, Pp 413-420 (2012)
Base-promoted glycosylation is a recently established stereoselective and regioselective approach for the assembly of di- and oligosaccharides by using partially protected acceptors and glycosyl halide donors. Initial studies were performed on partia
Externí odkaz:
https://doaj.org/article/540e6dfa26bf47c79d37b11630f3274a
Autor:
Louise Kristine Vigsnæs, Marta Hanna Mikš, Agnes Meszaros-Matwiejuk, Christoph H. Röhrig, Buket Soyyılmaz, Martin Matwiejuk
Publikováno v:
Nutrients
Nutrients, Vol 13, Iss 2737, p 2737 (2021)
Nutrients, Vol 13, Iss 2737, p 2737 (2021)
Human milk oligosaccharides (HMOs) are non-digestible and structurally diverse complex carbohydrates that are highly abundant in human milk. To date, more than 200 different HMO structures have been identified. Their concentrations in human milk vary
Autor:
Martin Matwiejuk, Joachim Thiem
Publikováno v:
European Journal of Organic Chemistry. 2012:2180-2187
A comprehensive acidity study of carbohydrate hydroxy groups has been carried out. Relative acidities (Ke) were determined spectrophotometrically for partially methylated methyl α-D-glycopyranosides. Apparently, the acidity is strongly affected by i
Autor:
Martin Matwiejuk, Joachim Thiem
Publikováno v:
European Journal of Organic Chemistry. 2011:5860-5878
As an alternative concept for glycosylation, the prior activation of acceptor hydroxy groups for selective glycosidic bond formation, was investigated to give complex oligosaccharides. Oxyanions obtained from partially protected saccharides were glyc
Publikováno v:
Macromolecules. 43:3606-3612
Homooligomeric saccharides are of general interest with potential applications in chemical, pharmaceutical, and food industry as well as for materials with novel properties. This contribution describes a methodology of a base-promoted “single step
Autor:
Joachim Thiem, Martin Matwiejuk
Publikováno v:
ChemInform. 42
The absolute and relative yields of the NaH promoted glycosylation of trimethylated α-D-glucopyranosides with 2,3,4,6-tetra-O-methyl-α-D-galactopyranosyl chloride indicate a reactivity sequence of isolated OH groups of 2-OH < 4-OH < 6-OH < 3-OH.
Autor:
Joachim Thiem, Martin Matwiejuk
Publikováno v:
Chemical Communications. 47:8379
Saccharide oxyanions obtained by base treatment could be employed in glycosylation to give oligosaccharides with high stereo- and regioselectivities.