Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Martin M. Lee"'
Autor:
Martin M. Lee, Christopher Ray, Fadie T. Coleman, Gerald B. Pier, Nina Reiniger, David E. Golan
Publikováno v:
Infection and Immunity. 75:1598-1608
Innate immunity is critical for clearing Pseudomonas aeruginosa from the lungs. In response to P. aeruginosa infection, a central transcriptional regulator of innate immunity—NF-κB—is translocated within 15 min to the nuclei of respiratory epith
Publikováno v:
Science. 307:1778-1781
The mammalian intestine harbors a beneficial microbiota numbering approximately 10 12 organisms per gram of colonic content. The host tolerates this tremendous bacterial load while maintaining the ability to efficiently respond to pathogenic organism
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 15:339-353
Inhaled particles may land on the surface of the lung’s airspaces. Upon making contact with the airway wall, the processes of retention and clearance begin. Particle retention depends on many factors; among these are: (1) particle size, shape, solu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1181:223-232
Intraperitoneal (i.p.) injection of crocidolite asbestos was used to induce mesotheliomas in rats. The morphological changes of the mesothelial cells were studied by light and electron microscopy and by cytologic examination of peritoneal washings. A
Publikováno v:
Pure and Applied Chemistry. 64:1745-1750
The pulmonary surfactant film at the alveolar air-liquid interface reduces the surface tension to a value below 1 mN/m on lung deflation. In addition to a low and stable surface tension, interdependence provided by the fibrous continuum enables the l
Publikováno v:
Biorheology. 28:39-52
We studied several non-Newtonian fluids to determine how closely they simulate the flow behavior of human blood. The viscous and viscoelastic properties of these fluids were compared with human blood samples in steady flow and transient flow Couette
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 287(6)
Submucosal glands are the primary source of airway mucus, a critical component of lung innate defenses. Airway glands are defective in cystic fibrosis (CF), showing a complete absence of secretion to vasoactive intestinal peptide or forskolin, which
Publikováno v:
American journal of respiratory cell and molecular biology. 22(3)
We compared the action of methacholine (MCh) and uridine 5'-triphosphate (UTP) with and without pretreatment with the chloride channel blocker 4,4'-diisothiocyano-2,2'-stilbenedisulfonate (DIDS) on the transepithelial potential difference (PD), the m
Publikováno v:
Respiration physiology. 109(1)
We measured the surface tension in the trachea of the non-anaesthetised horse from the spreading behaviour of fluid drops, using videotracheoscopy. To do this, we placed small oil drops onto the tracheal wall with a thin Teflon tubing inserted into a