Zobrazeno 1 - 10 of 31 pro vyhledávání: '"Martin M. Dokter"'
1
Akademický článek
A Kinase Interacting Protein 1 (AKIP1) promotes cardiomyocyte elongation and physiological cardiac remodelling
Autor: Kirsten T. Nijholt, Pablo I. Sánchez-Aguilera, Harmen G. Booij, Silke U. Oberdorf-Maass, Martin M. Dokter, Anouk H. G. Wolters, Ben N. G. Giepmans, Wiek H. van Gilst, Joan H. Brown, Rudolf A. de Boer, Herman H. W. Silljé, B. Daan Westenbrink
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract A Kinase Interacting Protein 1 (AKIP1) is a signalling adaptor that promotes physiological hypertrophy in vitro. The purpose of this study is to determine if AKIP1 promotes physiological cardiomyocyte hypertrophy in vivo. Therefore, adult ma
Externí odkaz: https://doaj.org/article/ed562cee66ed427ca8cecb89312bca87
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2
Akademický článek
Sexual dimorphism in selenium deficiency is associated with metabolic syndrome and prevalence of heart disease
Autor: Eerde H. Weening, Ali A. Al-Mubarak, Martin M. Dokter, Kenneth Dickstein, Chim C. Lang, Leong L. Ng, Marco Metra, Dirk J. van Veldhuisen, Daan J. Touw, Rudolf A. de Boer, Ron T. Gansevoort, Adriaan A. Voors, Stephan J. L. Bakker, Peter van der Meer, Nils Bomer
Publikováno v: Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-11 (2023)
Abstract Background Serum selenium levels have been associated with the incidence of heart failure (HF) and signs of the metabolic syndrome. In addition, notable differences have been reported between males and females in food intake and micronutrien
Externí odkaz: https://doaj.org/article/0e391b3e786140c3859e2ca8f1016731
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3
Selenium and outcome in heart failure
Autor: Nils Bomer, John G.F. Cleland, Chim C. Lang, Martin M Dokter, Martijn F Hoes, Jan IJmker, Nilesh J. Samani, Stefan D. Anker, Dirk J. van Veldhuisen, Daan J Touw, Peter van der Meer, Leong L. Ng, Jasper Tromp, Koen W. Streng, Hans L. Hillege, Adriaan A. Voors, Mathilde C.S.C. Vermeer, Niels Grote Beverborg
Publikováno v: European Journal of Heart Failure, 22(8), 1415-1423. Wiley
European Journal of Heart Failure
Aims:\ud Severe deficiency of the essential trace element selenium can cause myocardial dysfunction although the mechanism at cellular level is uncertain. Whether, in clinical practice, moderate selenium deficiency is associated with worse symptoms a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9f47390ba7b63897b56f2a4d686585
https://hdl.handle.net/11370/58f7ed27-a486-4024-a587-7c1bcbe16e62
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4
Pectins from various sources inhibit galectin-3-related cardiac fibrosis
Autor: Pieter Muntendam, Carolin Gehlken, Martin M Dokter, Wiek H. van Gilst, Wouter C. Meijers, Henk A. Schols, Rudolf A. de Boer, A. Rogier van der Velde, Herman H W Silljé
Publikováno v: Current Research in Translational Medicine, 70(1):103321
Current Research in Translational Medicine 70 (2022) 1
Current Research in Translational Medicine, 70(1)
Purpose of the study: A major challenge in cardiology remains in finding a therapy for cardiac fibrosis. Inhibition of galectin-3 with pectins attenuates fibrosis in animal models of heart failure. The purpose of this study is to identify pectins wit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd67b1c6f4f133c4f9fe28bb8786a2d1
https://doi.org/10.1016/j.retram.2021.103321
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5
Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)-Related Cardiomyopathy
Autor: Tim R Eijgenraam, Cornelis J. Boogerd, Xiaoke Yin, Manuel Mayr, Lukas E Schmidt, Herman H W Silljé, Eva van Rooij, Peter van der Meer, Nienke M Stege, Martin M Dokter, Rudolf A. de Boer, Vivian Oliveira Nunes Teixeira, Jolanda van der Velden, Konstantinos Theofilatos
Publikováno v: Circulation-Heart failure, 14(11):e008532. LIPPINCOTT WILLIAMS & WILKINS
Circulation. Heart failure, 14(11). Lippincott Williams and Wilkins Ltd.
Circulation. Heart failure, 14(11). Lippincott Williams and Wilkins
Circulation. Heart Failure
Eijgenraam, T R, Boogerd, C J, Stege, N M, Oliveira Nunes Teixeira, V, Dokter, M M, Schmidt, L E, Yin, X, Theofilatos, K, Mayr, M, van der Meer, P, van Rooij, E, van der Velden, J, Silljé, H H W & de Boer, R A 2021, ' Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)-Related Cardiomyopathy : Development of PLN-R14del-Related Cardiomyopathy ', Circulation. Heart failure, vol. 14, no. 11, pp. e008532 . https://doi.org/10.1161/CIRCHEARTFAILURE.121.008532
Supplemental Digital Content is available in the text.
Background: The p.(Arg14del) pathogenic variant (R14del) of the PLN (phospholamban) gene is a prevalent cause of cardiomyopathy with heart failure. The exact underlying pathophysiology is un
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f4ffc1ac9b8e1747e73da8397147370
https://doi.org/10.1161/circheartfailure.121.008532
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6
Factor Xa Inhibition with Apixaban Does Not Influence Cardiac Remodelling in Rats with Heart Failure After Myocardial Infarction
Autor: Kirsten T Nijholt, Rudolf A. de Boer, Salva R. Yurista, Martin M Dokter, Dirk J. van Veldhuisen, Herman H W Silljé, B. Daan Westenbrink
Publikováno v: Cardiovascular Drugs and Therapy, 35, 953-963. SPRINGER
Cardiovascular Drugs and Therapy
Cardiovasc Drugs Ther
Background Heart failure (HF) is considered to be a prothrombotic condition and it has been suggested that coagulation factors contribute to maladaptive cardiac remodelling via activation of the protease-activated receptor 1 (PAR1). We tested the hyp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fbe69b4dbcf8929667a77dd3210491
https://research.rug.nl/en/publications/c7bac4b0-6f6d-447c-92ed-2d8ca568e9e3
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7
The effects of liraglutide and dapagliflozin on cardiac function and structure in a multi-hit mouse model of Heart Failure with Preserved Ejection Fraction
Autor: Cornelis J. Boogerd, Martin M Dokter, B. Daan Westenbrink, Herman H W Silljé, George Markousis-Mavrogenis, Rudolf A. de Boer, Laura M G Meems, Carolyn S.P. Lam, Elisabeth Maria Schouten, Coenraad Withaar, Adriaan A. Voors
Publikováno v: Cardiovascular Research
Cardiovascular Research, 117(9), 2108-2124. Oxford University Press
AIMS: Heart failure with preserved ejection fraction (HFpEF) is a multifactorial disease that constitutes several distinct phenotypes, including a common cardiometabolic phenotype with obesity and type 2 diabetes mellitus. Treatment options for HFpEF
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36b6416d9d8bfc8dbbe4bcf73e379b1
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8
Tumour biomarkers: association with heart failure outcomes
Autor: R. A. De Boer, M. Metra, C. Shi, Martin M Dokter, H. H. Van Der Wal, J. Post, F. Zannad, Adriaan A. Voors, Chim C. Lang, F. van den Berg, John G.F. Cleland, P. L. van Haelst, Jourik A. Gietema, L. Huizinga, D. J. Van Veldhuisen, Kenneth Dickstein, Pietro Ameri, Nilesh J. Samani, Marco Canepa, Leong L. Ng, M. Vriesema, Herman H W Silljé, Stefan D. Anker
Publikováno v: Journal of Internal Medicine
Journal of Internal Medicine, 2020, 288 (2), pp.207-218. ⟨10.1111/joim.13053⟩
Journal of Internal Medicine, 288(2), 207-218. Wiley
Journal of Internal Medicine, Wiley, 2020, 288 (2), pp.207-218. ⟨10.1111/joim.13053⟩
International audience; Background: There is increasing recognition that heart failure (HF) and cancer are conditions with a number of shared characteristics.Objectives: To explore the association between tumour biomarkers and HF outcomes.Methods: In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f8f62717f9e72a22640ecd5cfe68797
http://hdl.handle.net/11567/1024218
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10
The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure
Autor: Michelle Chan, Carolyn S.P. Lam, Leong L. Ng, Kenneth Dickstein, Faiez Zannad, Johanna E. Emmens, Bernadet T. Santema, Michiel Rienstra, Adriaan A. Voors, Marco Metra, Rudolf A. de Boer, Chim C. Lang, Pim van der Harst, Jasper Tromp, Peter van der Meer, Janny Takens, Kevin Damman, John G.F. Cleland, Martin M Dokter, Jozine M. ter Maaten, Haye H. van der Wal, Stefan D. Anker, Dirk J. van Veldhuisen, Nilesh J. Samani
Publikováno v: Clinical Research in Cardiology
Clinical Research in Cardiology, Springer Verlag, 2020, 109 (3), pp.331-338. ⟨10.1007/s00392-019-01513-y⟩
Clinical Research in Cardiology, 109(3), 331-338. SPRINGER HEIDELBERG
Background In heart failure (HF), levels of NT-proBNP are influenced by the presence of concomitant atrial fibrillation (AF), making it difficult to distinguish between HF versus AF in patients with raised NT-proBNP. It is unknown whether levels of G
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20d4b6fbdf0c79feeb7624b2c2be01d
http://hdl.handle.net/11379/517496
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