Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Martin M Pike"'
Autor:
Humberto Mestre, Lauren M Hablitz, Anna LR Xavier, Weixi Feng, Wenyan Zou, Tinglin Pu, Hiromu Monai, Giridhar Murlidharan, Ruth M Castellanos Rivera, Matthew J Simon, Martin M Pike, Virginia Plá, Ting Du, Benjamin T Kress, Xiaowen Wang, Benjamin A Plog, Alexander S Thrane, Iben Lundgaard, Yoichiro Abe, Masato Yasui, John H Thomas, Ming Xiao, Hajime Hirase, Aravind Asokan, Jeffrey J Iliff, Maiken Nedergaard
Publikováno v:
eLife, Vol 7 (2018)
The glymphatic system is a brain-wide clearance pathway; its impairment contributes to the accumulation of amyloid-β. Influx of cerebrospinal fluid (CSF) depends upon the expression and perivascular localization of the astroglial water channel aquap
Externí odkaz:
https://doaj.org/article/9fe3ab146a0849b2a74eb8c9bba7a959
Autor:
Merryl R Lobo, Ayaka Kukino, Huong Tran, Matthias C Schabel, Charles S Springer, G Yancey Gillespie, Marjorie R Grafe, Randall L Woltjer, Martin M Pike
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144488 (2015)
Prognosis remains extremely poor for malignant glioma. Targeted therapeutic approaches, including single agent anti-angiogenic and proteasome inhibition strategies, have not resulted in sustained anti-glioma clinical efficacy. We tested the anti-glio
Externí odkaz:
https://doaj.org/article/86bc21be40ba48b5a826ab59c89fd43c
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114110 (2014)
We have previously reported that the in vivo anti-glioma efficacy of the anti-angiogenic receptor tyrosine kinase inhibitor cediranib is substantially enhanced via combination with the late-stage autophagy inhibitor quinacrine. The current study inve
Externí odkaz:
https://doaj.org/article/d35f347a42d24bd2b72c9bdd3d826217
Autor:
Thierno M. Bah, Elyse M. Allen, Manuel Garcia-Jaramillo, Ruby Perez, Yalda Zarnegarnia, Catherine M. Davis, Madeline B. Bloom, Armando A. Magana, Jaewoo Choi, Gerd Bobe, Martin M. Pike, Jacob Raber, Claudia S. Maier, Nabil J. Alkayed
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Vascular cognitive impairment (VCI) is the second most common cause of dementia. There is no treatment for VCI, in part due to a lack of understanding of the underlying mechanisms. The G-protein coupled receptor 39 (GPR39) is regulated by arachidonic
Externí odkaz:
https://doaj.org/article/a9fb7d8244654c23a74ec2a4b5266182
Autor:
Charles S. Springer, Eric M. Baker, Xin Li, Brendan Moloney, Gregory J. Wilson, Martin M. Pike, Thomas M. Barbara, William D. Rooney, Jeffrey H. Maki
Publikováno v:
NMR in Biomedicine. 36
Evidence mounts that the steady-state cellular water efflux (unidirectional) first-order rate constant (k
Autor:
Catherine M. Davis, Wenri H. Zhang, Thierno M. Bah, Natalie E. Roese, Elyse M. Allen, Philberta Leung, Sydney J. Boutros, Tessa Marzulla, Esha Patel, Xiao Nie, Farah N. Alkayed, Justin H. Huang, Michael A. Jensen, Jacob Raber, Martin M. Pike, Nabil J. Alkayed
Publikováno v:
npj Aging. 8
Soluble epoxide hydrolase (sEH) is upregulated in microvascular endothelium of human brain with vascular cognitive impairment (VCI). Transgenic endothelial expression of human sEH in mice (Tie2hsEH) induces endothelial dysfunction (ED), a pathogeneti
Autor:
Charles S. Springer, Eric M. Baker, Xin Li, Brendan Moloney, Martin M. Pike, Gregory J. Wilson, Valerie C. Anderson, Manoj K. Sammi, Mark G. Garzotto, Ryan P. Kopp, Fergus V. Coakley, William D. Rooney, Jeffrey H. Maki
Publikováno v:
NMR in biomedicineREFERENCES. 36(1)
We introduce a new
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-19 (2021)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS
Background Understanding molecular transport in the brain is critical to care and prevention of neurological disease and injury. A key question is whether transport occurs primarily by diffusion, or also by convection or dispersion. Dynamic contrast-
Autor:
Zhenzhou Li, Heather L. McConnell, Teresa L. Stackhouse, Martin M. Pike, Wenri Zhang, Anusha Mishra
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Neurovascular coupling, the process by which neuronal activity elicits increases in the local blood supply, is impaired in stroke patients in brain regions outside the infarct. Such impairment may contribute to neurological deterioration over time, b
Autor:
Martin M. Pike, Heather L. McConnell, Zhen-Zhou Li, Anusha Mishra, Teresa L. Stackhouse, Wenri Zhang
Neurovascular coupling, the process by which neuronal activity elicits increases in the local blood supply, is impaired in stroke patients in brain regions outside the infarct. Such impairment may contribute to neurological deterioration over time, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a03c957615f8a43f02ceb75363b424a
https://doi.org/10.1101/2021.08.25.457547
https://doi.org/10.1101/2021.08.25.457547