Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Martin Little"'
Autor:
Thomas Starkey, Maria C. Ionescu, Michael Tilby, Martin Little, Emma Burke, Matthew W. Fittall, Sam Khan, Justin K. H. Liu, James R. Platt, Rosie Mew, Arvind R. Tripathy, Isabella Watts, Sophie Therese Williams, Nathan Appanna, Youssra Al-Hajji, Matthew Barnard, Liza Benny, Alexander Burnett, Jola Bytyci, Emma L. Cattell, Vinton Cheng, James J. Clark, Leonie Eastlake, Kate Gerrand, Qamar Ghafoor, Simon Grumett, Catherine Harper-Wynne, Rachel Kahn, Alvin J. X. Lee, Oliver Lomas, Anna Lydon, Hayley Mckenzie, NCRI Consumer Forum, Hari Panneerselvam, Jennifer S. Pascoe, Grisma Patel, Vijay Patel, Vanessa A. Potter, Amelia Randle, Anne S. Rigg, Tim M. Robinson, Rebecca Roylance, Tom W. Roques, Stefan Rozmanowski, René L. Roux, Ketan Shah, Remarez Sheehan, Martin Sintler, Sanskriti Swarup, Harriet Taylor, Tania Tillett, Mark Tuthill, Sarah Williams, Yuxin Ying, Andrew Beggs, Tim Iveson, Siow Ming Lee, Gary Middleton, Mark Middleton, Andrew Protheroe, Tom Fowler, Peter Johnson, Lennard Y. W. Lee
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Patients with cancer are at increased risk of hospitalisation and mortality following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the SARS-CoV-2 phenotype evolution in patients with cancer since 2020 has
Externí odkaz:
https://doaj.org/article/b2a7d9f7273c4fa49fa236821ef7154d
Publikováno v:
Exploration of Targeted Anti-tumor Therapy, Vol 3, Iss 2, Pp 172-199 (2022)
The majority of breast cancers express the estrogen receptor (ER) and for this group of patients, endocrine therapy is the cornerstone of systemic treatment. However, drug resistance is common and a focus for breast cancer preclinical and clinical re
Externí odkaz:
https://doaj.org/article/652669df8df04cf0a2f4e0478567df96
Autor:
Matthew Fittall, Justin Liu, James Platt, Maria Ionescu, Remarez Sheehan, Sukhmunni Johal, Rosie Mew, James Clark, Izzy Watts, Arvind Tripathy, Martin Little, Grisma Patel, Hari Panneerselvam, Nathan Appanna, Emma Burke, Hayley McKenzie, Michael Tilby, Sam Khan, Lennard Y. W. Lee
Publikováno v:
British Journal of Cancer. 128:1977-1980
The COVID-19 pandemic has led to a range of novel and adaptive research designs. In this perspective, we use our experience coordinating the National COVID Cancer Antibody Survey to demonstrate how a balance between speed and integrity can be achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec05743b3a1591814d55068e68c5585c
https://doi.org/10.1038/s41416-023-02251-9
https://doi.org/10.1038/s41416-023-02251-9
Autor:
Nathan Appanna, Grisma Patel, Emma Burke, Alexander Burnett, James Clark, Rosie Mew, Sam Khan, Martin Little, Justin Liu, Hari Panneerselvam, Vijay Patel, James Platt, Michael Tilby, Isabella Watts, Catherine Harper‐Wynne, Lennard Y. W. Lee
Publikováno v:
International Journal of Cancer. 152:1275-1277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f356ddbf2715b8420070ed7e8fdf2365
https://doi.org/10.1002/ijc.34387
https://doi.org/10.1002/ijc.34387
Autor:
Susana Banerjee, Vasiliki Michalarea, Joo Ern Ang, Alvaro Ingles Garces, Andrea Biondo, Ionut-Gabriel Funingana, Martin Little, Ruth Ruddle, Florence Raynaud, Ruth Riisnaes, Bora Gurel, Sue Chua, Nina Tunariu, Joanna C. Porter, Toby Prout, Mona Parmar, Anna Zachariou, Alison Turner, Ben Jenkins, Stuart McIntosh, Ed Ainscow, Anna Minchom, Juanita Lopez, Johann de Bono, Robert Jones, Emma Hall, Natalie Cook, Bristi Basu, Udai Banerji
Publikováno v:
Clinical Cancer Research. 28:4634-4641
Purpose: CT900 is a novel small molecule thymidylate synthase inhibitor that binds to α-folate receptor (α-FR) and thus is selectively taken up by α-FR–overexpressing tumors. Patients and Methods: A 3+3 dose escalation design was used. During do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acc878b283c3c6e9cd5e46255c97453
https://doi.org/10.1158/1078-0432.ccr-22-1268
https://doi.org/10.1158/1078-0432.ccr-22-1268
Autor:
Udai Banerji, Bristi Basu, Natalie Cook, Emma Hall, Robert Jones, Johann de Bono, Juanita Lopez, Anna Minchom, Ed Ainscow, Stuart McIntosh, Ben Jenkins, Alison Turner, Anna Zachariou, Mona Parmar, Toby Prout, Joanna C. Porter, Nina Tunariu, Sue Chua, Bora Gurel, Ruth Riisnaes, Florence Raynaud, Ruth Ruddle, Martin Little, Ionut-Gabriel Funingana, Andrea Biondo, Alvaro Ingles Garces, Joo Ern Ang, Vasiliki Michalarea, Susana Banerjee
Supplementary Figure from A Phase I Trial of CT900, a Novel α-Folate Receptor–Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2704c4994794b5ac32f8afd095444629
https://doi.org/10.1158/1078-0432.22489008
https://doi.org/10.1158/1078-0432.22489008
Autor:
Udai Banerji, Bristi Basu, Natalie Cook, Emma Hall, Robert Jones, Johann de Bono, Juanita Lopez, Anna Minchom, Ed Ainscow, Stuart McIntosh, Ben Jenkins, Alison Turner, Anna Zachariou, Mona Parmar, Toby Prout, Joanna C. Porter, Nina Tunariu, Sue Chua, Bora Gurel, Ruth Riisnaes, Florence Raynaud, Ruth Ruddle, Martin Little, Ionut-Gabriel Funingana, Andrea Biondo, Alvaro Ingles Garces, Joo Ern Ang, Vasiliki Michalarea, Susana Banerjee
Supplementary Table from A Phase I Trial of CT900, a Novel α-Folate Receptor–Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0475121ba5d79aa5db6a42030c640f34
https://doi.org/10.1158/1078-0432.22488999
https://doi.org/10.1158/1078-0432.22488999
Autor:
Udai Banerji, Bristi Basu, Natalie Cook, Emma Hall, Robert Jones, Johann de Bono, Juanita Lopez, Anna Minchom, Ed Ainscow, Stuart McIntosh, Ben Jenkins, Alison Turner, Anna Zachariou, Mona Parmar, Toby Prout, Joanna C. Porter, Nina Tunariu, Sue Chua, Bora Gurel, Ruth Riisnaes, Florence Raynaud, Ruth Ruddle, Martin Little, Ionut-Gabriel Funingana, Andrea Biondo, Alvaro Ingles Garces, Joo Ern Ang, Vasiliki Michalarea, Susana Banerjee
Purpose:CT900 is a novel small molecule thymidylate synthase inhibitor that binds to α-folate receptor (α-FR) and thus is selectively taken up by α-FR–overexpressing tumors.Patients and Methods:A 3+3 dose escalation design was used. During dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2962569a9f2efd37fe6e40c644a7cac
https://doi.org/10.1158/1078-0432.c.6532860
https://doi.org/10.1158/1078-0432.c.6532860
Autor:
Lennard Y.W. Lee, Maria C. Ionescu, Thomas Starkey, Martin Little, Michael Tilby, Arvind R. Tripathy, Hayley S. Mckenzie, Youssra Al-Hajji, Nathan Appanna, Matthew Barnard, Liza Benny, Alexander Burnett, Emma L. Cattell, James J. Clark, Sam Khan, Qamar Ghafoor, Hari Panneerselvam, George Illsley, Catherine Harper-Wynne, Rosie J. Hattersley, Alvin JX. Lee, Oliver Lomas, Justin KH. Liu, Amanda McCauley, Matthew Pang, Jennifer S. Pascoe, James R. Platt, Grisma Patel, Vijay Patel, Vanessa A. Potter, Amelia Randle, Anne S. Rigg, Tim M. Robinson, Tom W. Roques, René L. Roux, Stefan Rozmanowski, Harriet Taylor, Mark H. Tuthill, Isabella Watts, Sarah Williams, Andrew Beggs, Tim Iveson, Siow M. Lee, Gary Middleton, Mark Middleton, Andrew Protheroe, Matthew W. Fittall, Tom Fowler, Peter Johnson, Emma Kinloch, Emily Lam, Gillian Murphy, Malcolm Rhodes, Kate Robinson, Sanskriti Swarup, Keeley Bernhardt, Jola Bytyci, Yuxin Ying, Sukhmunni Johal, Remarez Sheehan
Publikováno v:
European journal of cancer (Oxford, England : 1990). 175
People living with cancer and haematological malignancies are at an increased risk of hospitalisation and death following infection with acute respiratory syndrome coronavirus 2. Coronavirus third dose vaccine boosters are proposed to boost waning im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b456df6d584137078ec70d3485af98d8
https://pubmed.ncbi.nlm.nih.gov/36084618
https://pubmed.ncbi.nlm.nih.gov/36084618
Autor:
Thomas Starkey, Maria C. Ionescu, Matthew W. Fittall, Michael Tilby, Alex Burnett, Rosie Hattersley, Sam Khan, Martin Little, Justin K. Liu, James R. Platt, Arvind Tripathy, Isabella Watts, Sophie Therese Williams, United Kingdom COVID Cancer Programme, Tom Fowler, Peter W. Johnson, Lennard Y. Lee
Publikováno v:
Cancer Research. 83:804-804
Background: People living with cancer are reported to be at increased risk of hospitalization and death following infection with acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This is proposed to be dependent on a combination of intrinsic pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d295325efd1e3b95f0f796d1e654f1ff
https://doi.org/10.1158/1538-7445.am2023-804
https://doi.org/10.1158/1538-7445.am2023-804