Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Martin Linster"'
Autor:
Meisam Yousefi, Wai Suet Lee, Wharton O. Y. Chan, Wei He, Marcus G. Mah, Cythia Lingli Yong, Joshua M. Deerain, Lijin Wang, Camille Arcinas, Biaoguo Yan, Dewei Tan, Wan Rong Sia, Akshamal M. Gamage, Jinxuan Yang, Alan Chen-Yu Hsu, Shang Li, Martin Linster, Xinglou Yang, Sujoy Ghosh, Danielle E. Anderson, Gavin J. D. Smith, Chee Wah Tan, Lin-Fa Wang, Yaw Shin Ooi
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
The emergence of novel betacoronaviruses has posed significant financial and human health burdens, necessitating the development of appropriate tools to combat future outbreaks. In this study, we have characterized a human cell line, IGROV-1, as a ro
Externí odkaz:
https://doaj.org/article/b47f4408b06d4266b90736a4ac87c4ae
Autor:
Marcus G. Mah, Martin Linster, Dolyce H. W. Low, Yan Zhuang, Jayanthi Jayakumar, Firdaus Samsudin, Foong Ying Wong, Peter J. Bond, Ian H. Mendenhall, Yvonne C. F. Su, Gavin J. D. Smith
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Bats are the reservoir for numerous human pathogens, including coronaviruses. Despite many coronaviruses having descended from bat ancestors, little is known about virus-host interactions and broader evolutionary history involving bats. Stud
Externí odkaz:
https://doaj.org/article/a295077d7afd4f22b024fac1177dda84
Autor:
Dolyce H.W. Low, Lena Ch'ng, Yvonne C.F. Su, Martin Linster, Rong Zhang, Yan Zhuang, Mackenzie L. Kwak, Sophie A. Borthwick, Alan T. Hitch, Gavin J.D. Smith, Ian H. Mendenhall
Publikováno v:
One Health, Vol 16, Iss , Pp 100529- (2023)
Orthonairovirus is a genus of viruses in the family Nairoviridae, order Bunyavirales, with a segmented circular RNA genome. They typically infect birds and mammals and are primarily transmitted by ectoparasites such as ticks. Four of nine Orthonairov
Externí odkaz:
https://doaj.org/article/97dc1e9a47fb41dea9b214feccbd377c
Autor:
Meisam Yousefi, Wai Suet Lee, Biaoguo Yan, Liang Cui, Cythia Lingli Yong, Xin Yap, Kwan Sing Leona Tay, Wenjie Qiao, Dewei Tan, Nur Insyirah Nurazmi, Martin Linster, Gavin J D Smith, Yie Hou Lee, Jan E Carette, Eng Eong Ooi, Kuan Rong Chan, Yaw Shin Ooi
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8, p e1010763 (2022)
Transmembrane Protein 41B (TMEM41B) and Vacuole Membrane Protein 1 (VMP1) are two ER-associated lipid scramblases that play a role in autophagosome formation and cellular lipid metabolism. TMEM41B is also a recently validated host factor required by
Externí odkaz:
https://doaj.org/article/28b45e66449148bc9ee132c210cd5d6c
Autor:
Heidi Auerswald, Dolyce H. W. Low, Jurre Y. Siegers, Teyputita Ou, Sonita Kol, Saraden In, Martin Linster, Yvonne C. F. Su, Ian H. Mendenhall, Veasna Duong, Gavin J. D. Smith, Erik A. Karlsson
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Bats are considered the natural reservoir of numerous emerging viruses such as severe acute respiratory syndrome coronaviruses (SARS-CoVs). There is a need for immortalized bat cell lines to culture and investigate the pathogenicity, replica
Externí odkaz:
https://doaj.org/article/2ed3c95bb0e6473e95827b03b7f2ef10
Autor:
Pilot Dovih, Eric D. Laing, Yihui Chen, Dolyce H. W. Low, B. R. Ansil, Xinglou Yang, Zhengli Shi, Christopher C. Broder, Gavin J. D. Smith, Martin Linster, Uma Ramakrishnan, Ian H. Mendenhall
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/911407afe1034d768f2e92962bfc5d0b
Autor:
Danielle E. Anderson, Chee Wah Tan, Wan Ni Chia, Barnaby E. Young, Martin Linster, JennyG. H. Low, Yee-Joo Tan, Mark I.-C. Chen, Gavin J. D. Smith, Yee Sin Leo, David C. Lye, Lin-Fa Wang
Publikováno v:
Emerging Microbes and Infections, Vol 9, Iss 1, Pp 900-902 (2020)
ABSTRACTDespite initial findings indicating that SARS-CoV and SARS-CoV-2 are genetically related belonging to the same virus species and that the two viruses used the same entry receptor, angiotensin-converting enzyme 2 (ACE2), our data demonstrated
Externí odkaz:
https://doaj.org/article/00cfe039fd8646cf8bc24dc32ec53072
Autor:
Anthony T. Tan, Martin Linster, Chee Wah Tan, Nina Le Bert, Wan Ni Chia, Kamini Kunasegaran, Yan Zhuang, Christine Y.L. Tham, Adeline Chia, Gavin J.D. Smith, Barnaby Young, Shirin Kalimuddin, Jenny G.H. Low, David Lye, Lin-Fa Wang, Antonio Bertoletti
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108728- (2021)
Summary: Virus-specific humoral and cellular immunity act synergistically to protect the host from viral infection. We interrogate the dynamic changes of virological and immunological parameters in 12 patients with symptomatic acute SARS-CoV-2 infect
Externí odkaz:
https://doaj.org/article/c8f64ca8ef0343c9be0d502c42de65fd
Autor:
Yihui Chen, Marcus G. Mah, Jenny G.H. Low, Eng Eong Ooi, Yvonne C.F. Su, Mahesh Moorthy, Gavin J.D. Smith, Martin Linster
Publikováno v:
Heliyon, Vol 7, Iss 2, Pp e06329- (2021)
Pathogens that cause upper respiratory infections are numerous and specific preventive and therapeutic strategies are scarce. In order to ascertain the etiological agents resulting in upper respiratory tract infections (URTI) in adults in Singapore,
Externí odkaz:
https://doaj.org/article/697dd8193f3248d9b86046179ece75dd
Autor:
Yvonne C. F. Su, Danielle E. Anderson, Barnaby E. Young, Martin Linster, Feng Zhu, Jayanthi Jayakumar, Yan Zhuang, Shirin Kalimuddin, Jenny G. H. Low, Chee Wah Tan, Wan Ni Chia, Tze Minn Mak, Sophie Octavia, Jean-Marc Chavatte, Raphael T. C. Lee, Surinder Pada, Seow Yen Tan, Louisa Sun, Gabriel Z. Yan, Sebastian Maurer-Stroh, Ian H. Mendenhall, Yee-Sin Leo, David Chien Lye, Lin-Fa Wang, Gavin J. D. Smith
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT To date, limited genetic changes in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome have been described. Here, we report a 382-nucleotide (nt) deletion in SARS-CoV-2 that truncates open reading frame 7b (ORF7b) and OR
Externí odkaz:
https://doaj.org/article/78c2b3eb00ce455dbe637bf4420b2c4b