Zobrazeno 1 - 10
of 411
pro vyhledávání: '"Martin Leo-Hansmann"'
Autor:
Timothy Warwick, Giulia Karolin Buchmann, Beatrice Pflüger-Müller, Manuela Spaeth, Christoph Schürmann, Wesley Abplanalp, Lukas Tombor, David John, Andreas Weigert, Martin Leo-Hansmann, Stefanie Dimmeler, Ralf P. Brandes
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Treatment of vascular stenosis with angioplasty results in acute vascular damage, which may lead to restenosis. Owing to the highly complex cellularity of blood vessels, the healing response following this damage is incompletely understood. To gain f
Externí odkaz:
https://doaj.org/article/454a1536af07482ea7ac4e54de55b5f6
Autor:
Patrick Wagner, Nils Strodthoff, Patrick Wurzel, Arturo Marban, Sonja Scharf, Hendrik Schäfer, Philipp Seegerer, Andreas Loth, Sylvia Hartmann, Frederick Klauschen, Klaus-Robert Müller, Wojciech Samek, Martin-Leo Hansmann
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Histological sections of the lymphatic system are usually the basis of static (2D) morphological investigations. Here, we performed a dynamic (4D) analysis of human reactive lymphoid tissue using confocal fluorescent laser microscopy in comb
Externí odkaz:
https://doaj.org/article/4de9a7fd1a5b45b0a1ee9bb5a086094b
Autor:
Heike Horn, Vindi Jurinovic, Ellen Leich, Sabrina Kalmbach, Julia Bausinger, Annette M. Staiger, Katrin S. Kurz, Peter Möller, Heinz-Wolfram Bernd, Alfred C. Feller, Karoline Koch, Wolfram Klapper, Harald Stein, Martin-Leo Hansmann, Sylvia Hartmann, Gabriel Scheubeck, Martin Dreyling, Wolfgang Hiddemann, Klaus Herfarth, Marianne Engelhard, Andreas Rosenwald, Eva Hoster, German Ott, for the German Low-Grade Lymphoma Study Group (GLSG)
Publikováno v:
HemaSphere, Vol 6, Iss 9, p e767 (2022)
Recently, we have developed novel highly promising gene expression (GE) classifiers discriminating localized nodal (LFL) from systemic follicular lymphoma (SFL) with prognostic impact. However, few data are available in LFL especially concerning hots
Externí odkaz:
https://doaj.org/article/053c8564099e49fb9e4006cd11665282
Autor:
Oliver Waidmann, Thomas Pleli, Andreas Weigert, Esther Imelmann, Bianca Kakoschky, Christian Schmithals, Claudia Döring, Matthias Frank, Thomas Longerich, Verena Köberle, Martin-Leo Hansmann, Bernhard Brüne, Stefan Zeuzem, Albrecht Piiper, Ivan Dikic
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract The nuclear factor kappa beta (NFκB) signaling pathway plays an important role in liver homeostasis and cancer development. Tax1-binding protein 1 (Tax1BP1) is a regulator of the NFκB signaling pathway, but its role in the liver and hepato
Externí odkaz:
https://doaj.org/article/740d319af09b47b9b936f1021dead416
Autor:
Lorenz Thurner, Sylvia Hartmann, Natalie Fadle, Evi Regitz, Maria Kemele, Yoo-Jin Kim, Rainer Maria Bohle, Anna Nimmesgern, Lutz von Müller, Volkhard A. J. Kempf, Marc A. Weniger, Frank Neumann, Nadine Schneider, Martine Vornanen, Christer Sundström, Laurence de Leval, Andreas Engert, Dennis A. Eichenauer, Ralf Küppers, Klaus-Dieter Preuss, Martin-Leo Hansmann, Michael Pfreundschuh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nodular lymphocyte-predominant Hodgkin lymphoma with IgD+ lymphocyte-predominant (LP) cells is a rare clinical distinct lymphoma subset of B-cell origin. Here the authors show that antigens expressed by Moraxella catarrhalis are recognized by B cell
Externí odkaz:
https://doaj.org/article/99cb03073ee3445083e53f1da680f369
Autor:
Giulia K. Buchmann, Christoph Schürmann, Manuela Spaeth, Wesley Abplanalp, Lukas Tombor, David John, Timothy Warwick, Flávia Rezende, Andreas Weigert, Ajay M. Shah, Martin-Leo Hansmann, Norbert Weissmann, Stefanie Dimmeler, Katrin Schröder, Ralf P. Brandes
Publikováno v:
Redox Biology, Vol 45, Iss , Pp 102050- (2021)
Objective: The NADPH oxidase Nox4 is an important source of H2O2. Nox4-derived H2O2 limits vascular inflammation and promotes smooth muscle differentiation. On this basis, the role of Nox4 for restenosis development was determined in the mouse caroti
Externí odkaz:
https://doaj.org/article/1f3244d203f94483865ef6a1ec58116c
Autor:
Lilian Beeck, Markus Schneider, Navid Farsijani, Bettina Budeus, Julia Bein, Hendrik Schaefer, Sylvia Hartmann, Martin-Leo Hansmann, Ralf Küppers
Publikováno v:
HemaSphere, Vol 6, Pp 20-20 (2022)
Externí odkaz:
https://doaj.org/article/2e074d99a5974cbf9763eff6411b1b7c
Autor:
Henry Loeffler-Wirth, Markus Kreuz, Lydia Hopp, Arsen Arakelyan, Andrea Haake, Sergio B. Cogliatti, Alfred C. Feller, Martin-Leo Hansmann, Dido Lenze, Peter Möller, Hans Konrad Müller-Hermelink, Erik Fortenbacher, Edith Willscher, German Ott, Andreas Rosenwald, Christiane Pott, Carsten Schwaenen, Heiko Trautmann, Swen Wessendorf, Harald Stein, Monika Szczepanowski, Lorenz Trümper, Michael Hummel, Wolfram Klapper, Reiner Siebert, Markus Loeffler, Hans Binder, for the German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-20 (2019)
Abstract Background Germinal center-derived B cell lymphomas are tumors of the lymphoid tissues representing one of the most heterogeneous malignancies. Here we characterize the variety of transcriptomic phenotypes of this disease based on 873 biopsy
Externí odkaz:
https://doaj.org/article/eb092f16cead48828dfcb25f4bc14f5e
Autor:
Cristina López, Kortine Kleinheinz, Sietse M. Aukema, Marius Rohde, Stephan H. Bernhart, Daniel Hübschmann, Rabea Wagener, Umut H. Toprak, Francesco Raimondi, Markus Kreuz, Sebastian M. Waszak, Zhiqin Huang, Lina Sieverling, Nagarajan Paramasivam, Julian Seufert, Stephanie Sungalee, Robert B. Russell, Julia Bausinger, Helene Kretzmer, Ole Ammerpohl, Anke K. Bergmann, Hans Binder, Arndt Borkhardt, Benedikt Brors, Alexander Claviez, Gero Doose, Lars Feuerbach, Andrea Haake, Martin-Leo Hansmann, Jessica Hoell, Michael Hummel, Jan O. Korbel, Chris Lawerenz, Dido Lenze, Bernhard Radlwimmer, Julia Richter, Philip Rosenstiel, Andreas Rosenwald, Markus B. Schilhabel, Harald Stein, Stephan Stilgenbauer, Peter F. Stadler, Monika Szczepanowski, Marc A. Weniger, Marc Zapatka, Roland Eils, Peter Lichter, Markus Loeffler, Peter Möller, Lorenz Trümper, Wolfram Klapper, ICGC MMML-Seq Consortium, Steve Hoffmann, Ralf Küppers, Birgit Burkhardt, Matthias Schlesner, Reiner Siebert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Burkitt lymphoma (BL) is the most common pediatric B-cell lymphoma. Here, within the International Cancer Genome Consortium, the authors performed whole genome and transcriptome sequencing of 39 sporadic BL, describing the landscape of mutations, str
Externí odkaz:
https://doaj.org/article/0f2708368b2a4696b47220ee30732ce8
Autor:
Jennifer Hannig, Hendrik Schäfer, Jörg Ackermann, Marie Hebel, Tim Schäfer, Claudia Döring, Sylvia Hartmann, Martin-Leo Hansmann, Ina Koch
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 1, p e1007516 (2020)
In pathology, tissue images are evaluated using a light microscope, relying on the expertise and experience of pathologists. There is a great need for computational methods to quantify and standardize histological observations. Computational quantifi
Externí odkaz:
https://doaj.org/article/d929cc0ea4aa4315a6f94a6b34777cbb