Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Martin Lefrancois"'
Autor:
Guillaume Serwe, David Kachaner, Jessica Gagnon, Cédric Plutoni, Driss Lajoie, Eloïse Duramé, Malha Sahmi, Damien Garrido, Martin Lefrançois, Geneviève Arseneault, Marc K. Saba-El-Leil, Sylvain Meloche, Gregory Emery, Marc Therrien
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Cell motility is a critical feature of invasive tumour cells that is governed by complex signal transduction events. Particularly, the underlying mechanisms that bridge extracellular stimuli to the molecular machinery driving motility remain
Externí odkaz:
https://doaj.org/article/8d40dfb655684ea5b52431fa626afc2e
Autor:
Mona Nemer, Frédéric Charron, Martin Lefrancois, Paul-Henri Roméo, Ilan R. Kirsch, Gang He, Trang Hoang, Gorazd Krosl, Paul Jolicoeur
Publikováno v:
Scopus-Elsevier
ResearcherID
The Journal of Experimental Medicine
ResearcherID
The Journal of Experimental Medicine
In normal hemopoietic cells that are dependent on specific growth factors for cell survival, the expression of the basic helix-loop-helix transcription factor SCL/Tal1 correlates with that of c-Kit, the receptor for Steel factor (SF) or stem cell fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18623dfa7c1b55cf5991722ee4846f72
https://doi.org/10.1084/jem.188.3.439
https://doi.org/10.1084/jem.188.3.439
Autor:
Marianne Saint-Denis, Benoit Grondin, Trang Hoang, André Bédard, Mathieu Tremblay, Kazuo Waga, Martin Lefrancois, André Haman, Daniel G. Tenen
Transcription factors can function as DNA-binding-specific activators or as coactivators. c-Jun drives gene expression via binding to AP-1 sequences or as a cofactor for PU.1 in macrophages. c-Jun heterodimers bind AP-1 sequences with higher affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c9aa10d429f947acbfb690a5316ea2
https://europepmc.org/articles/PMC1899927/
https://europepmc.org/articles/PMC1899927/
Autor:
Marianne St Denis, Martin Lefrancois, Trang Hoang, Benoit Grondin, Daniel G. Tenen, Kazuo Waga
Publikováno v:
Blood. 104:3547-3547
The gene coding for the pro-inflammatory cytokine IL-1β is induced at the transcription level in differentiating macrophages and in stress response. Interestingly, PU.1 and C/EBPβ, two transcription factors implicated in IL-1β gene expression are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58af7a7fbb19b201db140b4164fe5ab3
https://doi.org/10.1182/blood.v104.11.3547.3547
https://doi.org/10.1182/blood.v104.11.3547.3547
Autor:
Dariel Ashton-Beaucage, Christian M Udell, Patrick Gendron, Malha Sahmi, Martin Lefrançois, Caroline Baril, Anne-Sophie Guenier, Jean Duchaine, Daniel Lamarre, Sébastien Lemieux, Marc Therrien
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001809 (2014)
The small GTPase RAS is among the most prevalent oncogenes. The evolutionarily conserved RAF-MEK-MAPK module that lies downstream of RAS is one of the main conduits through which RAS transmits proliferative signals in normal and cancer cells. Genetic
Externí odkaz:
https://doaj.org/article/01a103f9c3ac49eb8d3c6471457dc715