Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Martin Lablans"'
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background The low number of patients suffering from any given rare diseases poses a difficult problem for medical research: With the exception of some specialized biobanks and disease registries, potential study participants’ information
Externí odkaz:
https://doaj.org/article/6f592381ecb847c3bd2b77e2d17be5de
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Background Data analysis for biomedical research often requires a record linkage step to identify records from multiple data sources referring to the same person. Due to the lack of unique personal identifiers across these sources, record li
Externí odkaz:
https://doaj.org/article/73a13189e13045bcac0c23ae4f93de1c
Autor:
Christina Schüttler, Hans-Ulrich Prokosch, Michael Hummel, Martin Lablans, Björn Kroll, Cäcilia Engels, German Biobank Alliance IT development team
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257632 (2021)
BackgroundBiobanks ensure the long-term storage and accessibility of biospecimens and corresponding data sets. Thus, they form the foundation for many research projects which may contribute to improving medical care. With the establishment of the Ger
Externí odkaz:
https://doaj.org/article/012dd454511640118f2f25c174b49d41
Autor:
Martin Bialke, Thomas Bahls, Lars Geidel, Henriette Rau, Arne Blumentritt, Sandra Pasewald, Robert Wolff, Jonas Steinmann, Tobias Bronsch, Björn Bergh, Galina Tremper, Martin Lablans, Frank Ückert, Stefan Lang, Tarik Idris, Wolfgang Hoffmann
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-11 (2018)
Abstract Background The use of medical data for research purposes requires an informed consent of the patient that is compliant with the EU General Data Protection Regulation. In the context of multi-centre research initiatives and a multitude of cli
Externí odkaz:
https://doaj.org/article/1e5460624fe946ca9d1b9c9f75ef0474
Autor:
Marc Hinderer, Martin Boeker, Sebastian A. Wagner, Martin Lablans, Stephanie Newe, Jan L. Hülsemann, Michael Neumaier, Harald Binder, Harald Renz, Till Acker, Hans-Ulrich Prokosch, Martin Sedlmayr
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 17, Iss 1, Pp 1-14 (2017)
Abstract Background Pharmacogenomic clinical decision support systems (CDSS) have the potential to help overcome some of the barriers for translating pharmacogenomic knowledge into clinical routine. Before developing a prototype it is crucial for dev
Externí odkaz:
https://doaj.org/article/d340bc1f6ee54c928e18260e477c3155
Autor:
Matthias Mack, Julian Broche, Stephen George, Zahra Hajjari, Florian Janke, Lavanya Ranganathan, Mohammadreza Ashouri, Sabine Bleul, Alexander Desuki, Cecilia Engels, Stephanie M.J. Fliedner, Nils Hartmann, Michael Hummel, Melanie Janning, Alexander Kiel, Thomas Köhler, Sebastian Koschade, Martin Lablans, Mohamed Lambarki, Sonja Loges, Smiths Lueong, Sandra Meyer, Stephan Ossowski, Florian Scherer, Christopher Schroeder, Patrick Skowronek, Christian Thiede, Barbara Uhl, Jörg Janne Vehreschild, Nikolas von Bubnoff, Sebastian Wagner, Tamara V. Werner, C. Benedikt Westphalen, Patrizia Fresser, Holger Sültmann, Ingeborg Tinhofer, Christof Winter
Publikováno v:
Journal of Laboratory Medicine. 46:321-330
Testing for genetic alterations in tumor tissue allows clinicians to identify patients who most likely will benefit from molecular targeted treatment. EXLIQUID – exploiting liquid biopsies to advance cancer precision medicine – investigates the p
Autor:
Daniel Maier, Jörg Janne Vehreschild, Barbara Uhl, Sandra Meyer, Karin Berger-Thürmel, Melanie Boerries, Rickmer Braren, Viktor Grünwald, Boris Hadaschik, Stefan Palm, Susanne Singer, Martin Stuschke, David Juárez, Pierre Delpy, Mohamed Lambarki, Michael Hummel, Cäcilia Engels, Stefanie Andreas, Nicola Gökbuget, Kristina Ihrig, Susen Burock, Dietmar Keune, Angelika Eggert, Ulrich Keilholz, Hagen Schulz, Daniel Büttner, Steffen Löck, Mechthild Krause, Mirko Esins, Frank Ressing, Martin Schuler, Christian Brandts, Daniel P. Brucker, Gabriele Husmann, Thomas Oellerich, Patrick Metzger, Frederik Voigt, Anna L. Illert, Matthias Theobald, Thomas Kindler, Ursula Sudhof, Achim Reckmann, Felix Schwinghammer, Daniel Nasseh, Wilko Weichert, Michael von Bergwelt-Baildon, Michael Bitzer, Nisar Malek, Öznur Öner, Klaus Schulze-Osthoff, Stefan Bartels, Jörg Haier, Raimund Ammann, Anja Franziska Schmidt, Bernd Guenther, Melanie Janning, Bernd Kasper, Sonja Loges, Stephan Stilgenbauer, Peter Kuhn, Eugen Tausch, Silvana Runow, Alexander Kerscher, Michael Neumann, Martin Breu, Martin Lablans, Hubert Serve
Treatment concepts in oncology are becoming increasingly personalized and diverse. Successively, changes in standards of care mandate continuous monitoring of patient pathways and clinical outcomes based on large, representative real-world data. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc1bed2ee7d05f84f684acbb6581ce2
https://doi.org/10.21203/rs.3.rs-2162340/v1
https://doi.org/10.21203/rs.3.rs-2162340/v1
Autor:
Maxmilian Ataian, Erinna Bowman, Rumyana Proynova, Philip R. Quinlan, Emma Lawrence, Esther van Enckevort, Martin Lablans, Saher Maqsood, Heimo Müller, Robert Reihs, Petr Holub, Dominik František Bučík
Publikováno v:
Biopreservation and biobanking, 19(5), 414-421. MARY ANN LIEBERT, INC
Various biological resources, such as biobanks and disease-specific registries, have become indispensable resources to better understand the epidemiology and biological mechanisms of disease and are fundamental for advancing medical research. Neverth
Autor:
Galina Tremper, Florian Stampe, Andreas Borg, Esther Schmidt, Martin Lablans, Martin Bialke, David Croft, Torben Brenner
Publikováno v:
Methods of Information in Medicine. 60:021-031
Objectives Pseudonymization is an important aspect of projects dealing with sensitive patient data. Most projects build their own specialized, hard-coded, solutions. However, these overlap in many aspects of their functionality. As any re-implementat
Autor:
Matthias, Löbe, Martin, Bialke, Jonas, Bienzeisler, Johannes, Drepper, Thomas, Ganslandt, Sophie, Haderer, Detlef, Kraska, Martin, Lablans, Ulrich, Sax, Ronald, Speer, Sebastian, Stäubert, Knut, Kaulke
Publikováno v:
Studies in health technology and informatics. 293
The academic research environment is characterized by self-developed, innovative, customized solutions, which are often free to use for third parties with open-source code and open licenses. On the other hand, they are maintained only to a very limit