Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Martin L Read"'
Autor:
Riazul Zannat, Jonathan Lee, Jameel Muzaffar, Martin L. Read, Katie Brookes, Neil Sharma, Kristien Boelaert, Christopher J. McCabe, Hannah R. Nieto
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionRadioactive iodine (RAI) therapy is a critical component in the post-surgical management of thyroid cancer patients, as well as being a central therapeutic option in the treatment of hyperthyroidism. Previous work suggests that antithyroi
Externí odkaz:
https://doaj.org/article/b7b8f22aaf5a4010b7313cb20ff1f991
Autor:
Martin L. Read, Katie Brookes, Ling Zha, Selvambigai Manivannan, Jana Kim, Merve Kocbiyik, Alice Fletcher, Caroline M. Gorvin, George Firth, Gilbert O. Fruhwirth, Juan P. Nicola, Sissy Jhiang, Matthew D. Ringel, Moray J. Campbell, Kavitha Sunassee, Philip J. Blower, Kristien Boelaert, Hannah R. Nieto, Vicki E. Smith, Christopher J. McCabe
The sodium/iodide symporter (NIS) frequently shows diminished plasma membrane (PM) targeting in differentiated thyroid cancer (DTC), resulting in suboptimal radioiodide (RAI) treatment and poor prognosis. The mechanisms which govern the endocytosis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a757baf79e22f16a69b80be8a04fd2
https://doi.org/10.1101/2023.05.22.541733
https://doi.org/10.1101/2023.05.22.541733
Autor:
Christopher J. McCabe, Vicki E. Smith, Andrew S. Turnell, Kristien Boelaert, Moray J. Campbell, James A. Fagin, Iñigo Landa, Gareth G. Lavery, Rebecca J. Thompson, Mohammed Alshahrani, Hannah R. Nieto, Katie Brookes, Vikki L. Poole, Dean P. Larner, Caitlin E.M. Thornton, Martin L. Read, Alice Fletcher
The sodium iodide symporter (NIS) is required for iodide uptake, which facilitates thyroid hormone biosynthesis. NIS has been exploited for over 75 years in ablative radioiodine (RAI) treatment of thyroid cancer, where its ability to transport radioi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db5ac66f1269b400c2f72c32eb709142
https://doi.org/10.1158/0008-5472.c.6511641.v1
https://doi.org/10.1158/0008-5472.c.6511641.v1
Autor:
Christopher J. McCabe, Vicki E. Smith, Andrew S. Turnell, Kristien Boelaert, Moray J. Campbell, James A. Fagin, Iñigo Landa, Gareth G. Lavery, Rebecca J. Thompson, Mohammed Alshahrani, Hannah R. Nieto, Katie Brookes, Vikki L. Poole, Dean P. Larner, Caitlin E.M. Thornton, Martin L. Read, Alice Fletcher
Significant co-localization and trafficking of ARF4-dsRED and NIS-GFP proteins in co-incident vesicles at the plasma membrane in HeLa cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccf7fbfad38afb0c38830b1ca44f6ef
https://doi.org/10.1158/0008-5472.22423998
https://doi.org/10.1158/0008-5472.22423998
Autor:
Christopher J. McCabe, Vicki E. Smith, Andrew S. Turnell, Kristien Boelaert, Moray J. Campbell, James A. Fagin, Iñigo Landa, Gareth G. Lavery, Rebecca J. Thompson, Mohammed Alshahrani, Hannah R. Nieto, Katie Brookes, Vikki L. Poole, Dean P. Larner, Caitlin E.M. Thornton, Martin L. Read, Alice Fletcher
Fletcher A et al Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7d831a11ae599a023a286299514abd
https://doi.org/10.1158/0008-5472.22423983
https://doi.org/10.1158/0008-5472.22423983
Autor:
Christopher J. McCabe, Vicki E. Smith, Andrew S. Turnell, Kristien Boelaert, Moray J. Campbell, James A. Fagin, Iñigo Landa, Gareth G. Lavery, Rebecca J. Thompson, Mohammed Alshahrani, Hannah R. Nieto, Katie Brookes, Vikki L. Poole, Dean P. Larner, Caitlin E.M. Thornton, Martin L. Read, Alice Fletcher
Fletcher A et al Data Source File
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3ae1c4d813a054b62b9f2bac8f29ec
https://doi.org/10.1158/0008-5472.22423986.v1
https://doi.org/10.1158/0008-5472.22423986.v1
Autor:
Christopher J. McCabe, Kristien Boelaert, Jayne A. Franklyn, John C. Watkinson, Wendy E. Leadbeater, Jeffrey A. Knauf, Margaret C. Eggo, Adrian Warfield, Erica Gentilin, Vicki E. Smith, Robert I. Seed, Neil Sharma, Jim C.W. Fong, Greg D. Lewy, Martin L. Read
PDF file - 2.26MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135cefef3a1dba892a6fbb1f007ac725
https://doi.org/10.1158/0008-5472.22391399.v1
https://doi.org/10.1158/0008-5472.22391399.v1
Autor:
Christopher J. McCabe, Kristien Boelaert, Jayne A. Franklyn, John C. Watkinson, Wendy E. Leadbeater, Jeffrey A. Knauf, Margaret C. Eggo, Adrian Warfield, Erica Gentilin, Vicki E. Smith, Robert I. Seed, Neil Sharma, Jim C.W. Fong, Greg D. Lewy, Martin L. Read
Pituitary tumor transforming gene (PTTG)-binding factor (PBF or PTTG1IP) is a little characterized proto-oncogene that has been implicated in the etiology of breast and thyroid tumors. In this study, we created a murine transgenic model to target PBF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42353d8d2975333dc5409ddcf1604ee9
https://doi.org/10.1158/0008-5472.c.6503249.v1
https://doi.org/10.1158/0008-5472.c.6503249.v1
Autor:
Hannah Nieto, Martin L. Read, Christopher McCabe, Katie Brookes, Merve Kocbiyik, Neil Sharma, Alice Fletcher, Hisham Mehanna, Kristien Boelaert, Mohammed Alshahrani, Vicki Smith, Albert Nobre de Menezes, Caitlin Thornton, Jean-Baptiste Cazier
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 107:1392-1406
Context Thyroid cancer recurrence is associated with increased mortality and adverse outcomes. Recurrence risk is currently predicted using clinical tools, often restaging patients after treatment. Detailed understanding of recurrence risk at disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00cabb3f3e3a2e550ecc52ec7f471e2
https://doi.org/10.1210/clinem/dgab836
https://doi.org/10.1210/clinem/dgab836
Autor:
Merve Kocbiyik, Selvambigai Manivannan, Katie Brookes, Ling Zha, Hannah R Nieto, Martin L Read, Christopher J McCabe, Vicki E Smith
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6416328f3a192fb900d66dfd38145b46
https://doi.org/10.1530/endoabs.86.op6.3
https://doi.org/10.1530/endoabs.86.op6.3